Conserved Protein Domain Family
DnaG_DnaB_bind

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pfam08278: DnaG_DnaB_bind 
DNA primase DnaG DnaB-binding
Eubacterial DnaG primases interact with several factors to from the replisome. One of these factors in DnaB, a helicase. This domain has been demonstrated to be responsible for the interaction between DnaG and DnaB.
Statistics
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PSSM-Id: 311952
View PSSM: pfam08278
Aligned: 186 rows
Threshold Bit Score: 41.8244
Threshold Setting Gi: 502888317
Created: 26-Jul-2016
Updated: 4-Aug-2016
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81357144  468 GTLLRLVLQHPALAARLPVDLVPT----MNAEGEALVAIIDA---TntgdlaaNVGLgaLVERFR--E-TPHGETLAKTA 537
gi 81504107  465 QKVLRLLMRYPALAARLDADTRTQltapELPQGEVLSGLLAE---CdtagpemHFGA--FVERLG--Q-TPYAEAFAGLR 536
gi 122946693 465 QRVIQLLMCYPALSARLDEDARALllggESSDSEVLAHLVEA---CdsvqgevNFAA--FSEHLA--Q-SPYAEVYAVAR 536
gi 123081210 466 QRVIQLLMCYPSLAARLDGDARALlldpQHSGSEALGYLVSA---CdgiqgevNFAA--FSEQLA--Q-TPYADVYASAR 537
gi 759998394 528 rrllrlLLAHPALVAGLGDHQLELl--aHHPHLGLVRQLIGLastCga----aHAGA--LLQAADp-E-SDLARAIQDLS 597
gi 500196796 460 RQIMRLLVEHPVLAAELDQAALDVaahfAPERADMLVQLVTM---SremgvhaNFAT--LAELLRssG-SDFDTLVAEIA 533
gi 503770937 457 RQIIRLLVAHPAFASELDDAALDAvahfAPDRAEMLARLITA---ShamgeqaNFAT--LAEHLRegG-EDFESLIAEIA 530
gi 502997924 457 RQIMRLLVAHPQLAADLDAGALEAiariAPDQAEMLTHLVGV---AqgmgeqaNFAA--LVEHLRegG-PEFDSMIAEIA 530
gi 503158176 550 KRLLGLLLAHPELVDSMGDQQLEVi--dHGPHLGLVRDLIML---Aqas-garHVGA--LLEAAD--PdSDLATVLKGLR 619
gi 330428593 485 KRLLRLLLAHPELVSGLGDQQLEIl--eHGPHLILVRELIAL---Anmt-garHAGA--LLQAAE--PgSDLETVLATLT 554
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 81357144  538 GELVDAEFDEavVEVLFEDTLRKLHADTIAREIDGLTAREreSGL-SSIERHRLA 591
gi 81504107  537 VAVLNDDIELepATQEFDAAVQKMLAEPLRRELEMLQRKMe-GGHaTDADKERLR 590
gi 122946693 537 AAVLREEIEEapAIQDFDAAITKLLAEPLRRELDGLQAEVv-AGTaDEAAKQRMR 590
gi 123081210 538 TAVLREEIEEepATHEFDGAVHKLLAEPLEREQKALEAMVs-AGTaDEETKARYL 591
gi 759998394 598 TE-LMAQDLPd-PQAEWDDALRAIERQTVQDQCDRLIE----SGLeTAEDRRRYQ 646
gi 500196796 534 AESESDVDa---ARLELAGAIRQTKMKMLATEMETLIA----SGLsGEQAQARYR 581
gi 503770937 531 AESESETEa---ARLELAGAIRQTKMKTLKEELDQLAA----TGLgNDDARNRYR 578
gi 502997924 531 AESESEFDv---VRAEMGGAIRQARIRALDEEMQMLVT----SNLrTEEDRNRYR 578
gi 503158176 620 ADILSQEDLPd-PQTEWDDALRRIEFDSAKLEIAKLAA----AGLtTEEARKRYL 669
gi 330428593 555 PELLDQEDLPh-PQIEWNDALRRIELEAIKAEQSALVE----AGLrDDASRKRYQ 604
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