Conserved Protein Domain Family
DPM3

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pfam08285: DPM3 
Dolichol-phosphate mannosyltransferase subunit 3 (DPM3)
This family corresponds to subunit 3 of dolichol-phosphate mannosyltransferase, an enzyme which generates mannosyl donors for glycosylphosphatidylinositols, N-glycan and protein O- and C-mannosylation. DPM3 is an integral membrane protein and plays a role in stabilizing the dolichol-phosphate mannosyl transferase complex.
Statistics
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PSSM-Id: 336985
View PSSM: pfam08285
Aligned: 98 rows
Threshold Bit Score: 47.5421
Threshold Setting Gi: 552829880
Created: 24-Mar-2017
Updated: 23-May-2017
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74603698    7 TLLAFFALSAVYFALYSGVIpt-sEKVH-DEILPFLPWWTLVTFGAYSLGTLGWGVLTFKDKEDKYKELLNQIDEAKSFY 84
gi 20137719    7 VILYYVSLTILYRVTYLFDL----EEPW-STLRPYTPYLFILAFGSYLGITLLYNVATTNDKPEAYVDLVKDIKEAQDAL 81
gi 74876339    7 VFITFTFLMTFWLLLVLEKIqlnlSPSI-QSIIPFLPLYAVVCFGSYSLGVIAYNLLIMSDCKEASESLFDEIKEAKESL 85
gi 761905650  10 WLAIAAFFMELWYGLVVGWFpi-nISPQlYQVLLPMPLYAIMLLGCYSLIAVGYQLMTFSDCPEAADEIKQEIQMAKRDL 88
gi 395532200   7 WISTLLALMLIWLCLVQDLLnlgySQKF-HDVIVPLPVYLLVTAGSYSLATLGLRLASFNDCEEAAQELFLQIQEAQADL 85
gi 330792411   7 VFLTFASLMAVWFLILIEKIqlnlSEPV-QSIIPFLPLYALVVFGSYSLGVIAYNLLIMSDCKEAADSLYDEIKEAKESL 85
gi 674588520   7 WLSTAILLTALWLGALYSPIas-vPSIK-M-VVLLSPVI-IVILGIISLSYIMFGVFNFNDCPGEDEKLKQQIEEARKGL 82
gi 213402647   7 ILVYFILMSIFKNSLYLIDM----EEPW-ASIRPWTSIILLALYGVKLGFELLYNVANTHNKPEAYVDLVKDIKEAQDAL 81
gi 149573011   7 WLWALALLGSAWAALTLGPGsralPPPW-HQVLGPLPAYLLVVAGCYALGTVGYRVARFNDCEDAARELQAQIRQARADL 85
gi 301098816   7 WLAAFVVLFALWLLLLRYAAdhiqDSRV-QEVVMALPMYVLVSYGAYSLAVIALSVMAVQDCPEAAKELNQQVVEAKADL 85

                 ....*.
gi 74603698   85 KQKGID 90
gi 20137719   82 RSKGMT 87
gi 74876339   86 RAKGMK 91
gi 761905650  89 ASKGFK 94
gi 395532200  86 ASKGLK 91
gi 330792411  86 RSKGMK 91
gi 674588520  83 RNAGYK 88
gi 213402647  82 RAKGMV 87
gi 149573011  86 GRKGLR 91
gi 301098816  86 TKKGFi 91
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