Conserved Protein Domain Family
Spc24

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pfam08286: Spc24 
Spc24 subunit of Ndc80
Spc24 is a component of the evolutionarily conserved kinetochore-associated Ndc80 complex and is involved in chromosome segregation
Statistics
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PSSM-Id: 311957
View PSSM: pfam08286
Aligned: 83 rows
Threshold Bit Score: 51.0154
Threshold Setting Gi: 261289725
Created: 19-Jul-2016
Updated: 4-Aug-2016
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74687673  114 LEQQQFSIAKQLNEEQAAVAKKEVELGKWKTAKEDIEKVEIGeGD----Wa-----D---GKV------IRLKLFSEA-G 174
gi 81904610   83 LEVELQRTSKEDTCVQARLRQLITELQELREMEEELQRQERDvd-----------eD---NTVtipsavYVAHLYHQIsK 148
gi 754346076  83 IENDKFALAKSINHLDRDNQALTSTMHKLDGDLDAIQARRQAvEQa---RtvgvpqN---KSI--------VSLYMNItN 148
gi 147901526  85 IDRELQERMEKNASLESSIKFLQKDLEELKVMEEEIADMQREaDEdtttVi-----P---SAV------YLAKLFHNVtK 150
gi 972975086  87 LEKELQKSKSRKDMLQAEIEFLQKEIDSLREAEREVQVLQAEvDEd---Tt-----EiipSTK------YIVQLYHKVtK 152
gi 255074773  85 VEAEKRAAGEFLTHMEAEAQALEHMQAELKSQSANLKVKKQEvDAi---Em-----DdvpRAK------HELSLYAHIsK 150
gi 351710028  83 LEAELQKAGEEDAILRARLRYPSQELQELRELEAELDRQEREvd-----------eD---TTVtipaavYVAQLYRRIsK 148
gi 742218552  83 LEAELQRASEEDAHLKANLLQLTRELEELKEIEADLERQEKEvd-----------eD---TTVtipsavYVAQLYRRIsK 148
gi 126322841  83 IESELQKASEKNGSLKANLNLLTKELEELKEMEQDLLRMEGEvd-----------eD---TTVvipsavYVSQLYHQVsK 148
gi 261289725 148 LEAEKCQAEKQRQQTEQGVQSLMGKLEKLKEEKEAVGKQKESvt-----------qN---TTEalpdvrYLATLYTNVtK 213
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 74687673  175 FSLVSAkdgsNVTKV--LIRN--DAK---ED--VHSVVVD-N-S-RPKVYTANLIWSL 220
gi 81904610  149 IQWDYE-----CEPG--MIKG--IHHgptV---AQPIHLD-SaQ-LSPKFISDYLWSL 192
gi 754346076 149 IKWDFE----QDN----LVKGfvTKN---ND--VRPFSLD-P-KvQTPYFIANYLWEK 191
gi 147901526 151 IDWDY-----NCDPS--LIKG--IHY---GGdiAQPISIDsN-Q-HSKIFICNYLWSL 194
gi 972975086 153 IKWDF-----NTEPD--ILRG--VHF---GKdiVTPINLD-T-ReHSEGFISDYLWSL 196
gi 255074773 151 ISWQYE----TTDRIkgRVNA--HEG---KD--LQVIDYA-VgD-RSEYQLANDLWNL 195
gi 351710028 149 IEWDYE-----CEPG--AIRG--IHHgpsV---AQPVHLD-SaQ-LSKQFVSDYLWSL 192
gi 742218552 149 IEWDYE-----CEPG--MIKG--IHHgpsV---AQPIHLD-StQ-LSKKFISDYLWNL 192
gi 126322841 149 IEWDYE-----CEPT--IIKG--IHHgpnI---AQPIHLD-StQ-HSQKFISDYLWSL 192
gi 261289725 214 LKWDFS-----CGPD--EIKG--FVTcksD---VKPFSLN-SkQ-NSQFFVANYLWDL 257
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