Conserved Protein Domain Family
Sin3_corepress

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pfam08295: Sin3_corepress 
Sin3 family co-repressor
This domain is found on transcriptional regulators. It forms interactions with histone deacetylases.
Statistics
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PSSM-Id: 336989
View PSSM: pfam08295
Aligned: 109 rows
Threshold Bit Score: 91.1059
Threshold Setting Gi: 566152189
Created: 21-Mar-2017
Updated: 23-May-2017
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124462009  265 HPGYANIMKE---------DPKLPNVLNHLWVSVPf-gSEDY-SFSIM-RKNSFEEQLFKIEDEMFEYDVNINCYRRTIK 332
gi 74676102   497 SLTYRKLPDSwkqdkcsgrDDLDNSVLNDDYISVA---PKPShVKNIMhHENQYLQALQLVEDERYDYDRVLNTTESAIK 573
gi 224005188  683 SPSYRALPRDypnppcserSEEELKVLNDVWVSLPv-gSEESyTFRHM-RKNQYEETLFRCEDMRFEIDMCIDGNASTMQ 760
gi 298713557  528 TPSYRELPQDyqvtscsgrSPNEDAVLNDTWVSVPv-gSEDSgSFKHM-RRNPNEEQLFKVEDERFELDMLIDGVASAIA 605
gi 676395783  355 TPSYRALPTSmshprcggrSDLDQNVLNDVWVSQPvgsEETN-SFKHV-RKNVYEEELFKCEDERFELDMITDSNAAAIA 432
gi 855314974   20 TPSYHELPPQiprrvgsqrSYADSLVLNDNLVSQTt-gSEDL-SYIHM-RRNQYEEALFRCEDDRFEVDVILETTRSAIA 96
gi 695393761  715 TPSYRGLPASypippcshrSALEKQVCNDSWVSVPt-gSEDF-SFKSM-RKNQYEEALFKCEDERFEIDMVIEANASTIS 791
gi 891602438  495 GYLYRKIPAEkqkgtcsgrDALANSVLNDEYILVA---PKLTgIKNVKhSENQYLQALQLVEDERYEYDRILSVNQRAIK 571
gi 915010472  664 nGSYRKLPDEcnndtcsgrDALSWQVLNDRWALFPdssESQAr------QMNRHEEALLTLADSRYEWDLRVCLLESCLK 737
gi 401405571  362 GSSYRRLPPDwpllecsgrDALCWEVFNDSWASIPdssESQAr------FTNRHEEQLLLLEDTRYEWDLRIGRLEATLR 435
                          90
                  ....*....|....*.
gi 124462009  333 LLDQLIAGnN-QQAIE 347
gi 74676102   574 ILANFCEP-TiHEHLE 588
gi 224005188  761 RLSAIYDElQ-VLSEN 775
gi 298713557  606 RLEPAEEEiE-ALRat 620
gi 676395783  433 SLELINTAvQ-Qslrs 447
gi 855314974   97 QLHLLSSElE-AVQET 111
gi 695393761  792 VLEPLAHEiE-VLKKS 806
gi 891602438  572 LLAELCEPvNdEEHir 587
gi 915010472  738 RIEAIKQAlE-QFPEE 752
gi 401405571  436 RLERITEQlT-MIAPE 450
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