Conserved Protein Domain Family
Sin3_corepress

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pfam08295: Sin3_corepress 
Sin3 family co-repressor
This domain is found on transcriptional regulators. It forms interactions with histone deacetylases.
Statistics
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PSSM-Id: 311964
View PSSM: pfam08295
Aligned: 108 rows
Threshold Bit Score: 91.8494
Threshold Setting Gi: 566152189
Created: 22-Jul-2016
Updated: 4-Aug-2016
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124462009   265 HPGYANIMKE---------DPKLPNVLNHLWVSVPf-gSEDYSFSIMRKNSFEEQLFKIEDEMFEYDVNINCYRRTIKLL 334
gi 198423440   628 GSSYRALPSSfqqptctgrDDLCHEVLNDTWVSFPs-wSEDSQFVTSKKTPFEEHIYRCEDERYELDVVIETNLGAIRCL 706
gi 642013538    12 GSSYRALPKSytqpkctgrTPLCKEVLNDTWVSFPs-wSEDSTFVSSKKTQYEEHIYRCEDERFELDVVLETNLATIRAL 90
gi 1028711815  643 GASYCAVPSDyltpkcsgrTKMCYEVLNDTWVSFPt-wSEESSFATSRKTQYEEYMHRCEDERFELDLVMEVNLAAIYCL 721
gi 195996591   498 GASYRALPKTfnqpkcsgrSPLCKEVLNDTWVSFPs-wSEDSTFVSSRKTQFEEHIYRCEDERFELDIVIEANAATIKVL 576
gi 156385204   457 GTSYRALPKSytqpkcsgrSDMCKEVLNDTWVSFPs-wSEDTPFPGTRKTQYEEYIFRCEDERFELDVVLESNLSTIRVL 535
gi 541040505   571 GISYRSLPDSyarpvctgrTPLCQSVLNDTWVSFPswsSEDTSCVHSKKSQYEEFIYRTEDERYELDIVIEVNKAALETL 650
gi 170593427   510 GVSYRSLPESyekplcsgrTSLCESVLNDSWVSFPcwsSEDSSAVHSKKTQFEEFVFRTEDERYELDIVIEVNKTALEVL 589
gi 675888586   562 DISYLSLPKDhiharcsgrTAMCYEVLNDTHVSFPs-wSED-SSSVIKKTMAEEMIFRCEEERYQLDIILENMQSTLDVM 639
gi 313221042   427 GSSYRSMPKEhrrp--pskDPLASSVLNDVWVSLPt-wSEDPQFSSTKKNQYEDAIIRCEDERFELDNVIEANLHTIKIF 503
                           90
                   ....*....|...
gi 124462009   335 DQLIAGnNQQAIE 347
gi 198423440   707 EGINKKlSRMSEE 719
gi 642013538    91 EAVQRRlSRMTAE 103
gi 1028711815  722 EELTRRfNRMTPE 734
gi 195996591   577 ESVQKKlSRMNPD 589
gi 156385204   536 EAVQKKlQRMSSE 548
gi 541040505   651 EFLQRKmGRMKKE 663
gi 170593427   590 EMVQRKmLRMKNE 602
gi 675888586   640 RFVQWKmENMTCD 652
gi 313221042   504 EGVQKKmQRMKDD 516
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