2XID,5DCQ


Conserved Protein Domain Family
TED

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pfam08341: TED 
Click on image for an interactive view with Cn3D
Thioester domain
This domain is found near the N-terminus of a variety of bacterial surface proteins and pili. This domain contains an unusual covalent ester bond between a conserved cysteine and glutamine residue.
Statistics
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PSSM-Id: 337011
View PSSM: pfam08341
Aligned: 27 rows
Threshold Bit Score: 169.459
Threshold Setting Gi: 501966549
Created: 27-Mar-2017
Updated: 23-May-2017
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2XID_A       124 SVEAYNDFEEFSVltt---qnYAKFYYA-KNKNgSS----Q--VVYCFNADLKSPPDSEDGGKtmtpdfTtge------- 186
gi 75424181  371 SVEAYNDFMDEEVlsg--ftpYGKFYYA-TNKDkSS----Q--VVYCFNADLHSPPDSYDSGE------Tinpdts--tm 433
gi 75397896  390 SVEAYNDFEEFSVltt---qnYAKFYYA-KNKNgSS----Q--VVYCFNADLKSPPDSEDGGK------Tmtpdft---t 450
gi 122250731 155 SFEAYNDFSEYEIltt---qnYAKFYYA-KNQNgSK----Q--VVYCFNADLHSPPDSYDYGD------Niepdia--tg 216
gi 75442359   34 KYYGWNDGTRRDS--------PFFLYVSpQNDPkRElkdeC--IVYCFNRDKQWPETW-GVNR------Tfsqvqsevtf 96
gi 122541019  35 LYYGWNDGTRHNS--------PFFLYVTpENNPtRStddkY--VVYCFNRDREWPENW-DASR------Nfndvqndmvf 97
gi 75380721   37 QYYGWSVPTTNYD--------PSNLYVTpIGETtKKl--dI--PVYCFDYKFLEPLKWESEKA------Rpdy------- 91
5DCQ_D         2 lYYGWNDGTRQSS--------PYFLYVSpKNAPkRElkdeY--VVYCFNKKLYWPDQWESIYS------Nfndirsp-yn 64
gi 501966549  37 QYYGWSDGSSSY---------PSALYVTpVGDTtKK----IaiPVYCFDYKFQEPLAWKEITQ------Pshl------- 90
gi 198417343 383 SVEAYSDMQDSNYinpetftpYGKFYYA-KNKDkSS----Q--VVYCFNADLHSPPESEDGGG------Tidpdis--tm 447
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2XID_A       187 --vkYTHIAG--RDLFKYTVKPRDTDPd------TFLKH---IKKVIEKGYREKG--QAIEy-sGLTETQLRAATQLAIY 250
gi 75424181  434 kevkYTHTAG--SDLFKYALRPRDTNPe------DFLKH---IKKVIEKGYKKKG--DSYN---GLTETQFRAATQLAIY 497
gi 75397896  451 gevkYTHIAG--RDLFKYTVKPRDTDPd------TFLKH---IKKVIEKGYREKG--QAIEy-sGLTETQLRAATQLAIY 516
gi 122250731 217 rivkYTQVKG--VDLLKYTVNARTSNSs------QFLTW---IKKVIFKGYKGEG--DNIPs--GLTPTQFRAATQLAIY 281
gi 75442359   97 klplYEKKKGsdEVFKNNAPRFRGTVK-------NVTAA---LVAVLKSGYPTVK--Si----nHLDAEKSRKVTQLAIW 160
gi 122541019  98 klplYERKDGsdEVFKKNAPHFRGTVK-------NVTAA---LVAVLESGYPTVK--Ni----gQLDAEKGRKVTQLAIW 161
gi 75380721   92 -ltlYNKYEGlkEMLETKSQKDYITTEtek-klqGMKDKlpaLFTILSKGFPNHN--TELCkkySLSEQSARKVTQLALW 167
5DCQ_D        65 dlpvYEKKLGydGIFKQYAPDYKKDIS-------DIASA---LVAVLSNGYPTNK--SQLStsyHLNNDSSRKVTQLAIW 132
gi 501966549  91 --ivYDKYDGknLMAALVEKPNMVSYEtktklqtLLKTKsnlITAILSRGYPNKSffDKYk---KLTDEDKRRVTQCALW 165
gi 198417343 448 kevkYTHTAG--SDLFKYALRPRDTNPe------DFLKH---IKKVIEKGYNKKG--DSYN---GLTETQFRAATQLAIY 511
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2XID_A       251 YFTDSAelDKDKL----KDYHGFGDMNdstlAVA-KILV-----EYAQD-SNPPQLTDLDFFIPNN------NKYQSLIG 313
gi 75424181  498 YFTDSAdlKTLKTynngKGYHGFESMDektlA-VtKELI-----TYAQN-GSAPQLTNLDFFVPNN------SKDQSLIG 564
gi 75397896  517 YFTDSAe----lDkdklKDYHGFGDMNdstlA-VaKILV-----EYAQD-SNPPQLTDLDFFIPNN------NKYQSLIG 579
gi 122250731 282 YFTNSAdlETLKTydnnKGYHGFEDMNeatlK-VtKDLV-----AYALNnESANDLPDLDFLIPNN------NSYQSLVG 349
gi 75442359  161 YFSDSE--NDPDTylqpS--EKLTQEE----KTAfNSLVee-gkKAGET-LSSTGDYTLDIYITTDkny-aqKQYQNLLG 229
gi 122541019 162 FFSDNQ--DNPDDylqsS--EKLSEQE----KSAfKSLVek-gkKAGES-PLSNGSYTLDIYITTNtkytthKLYQNLLG 231
gi 75380721  168 CYTDDV--GKEELiqryIDSRGNEEQE----KQAlEFLIe----EGRKPiKIEFPENKLTFYIRTKdsr-ygPRYQNLIG 236
5DCQ_D       133 YFSDSL----TKEylkdTGGYNLNDME----KKAlDFLIsk--gEDSKL-KSEQSNYSLDIYVYQSgghdhmKDYQNLLG 201
gi 501966549 166 YHTDNi--SEQDLitkhLDGDSGEKSQ------AlKELIgvvknTSNEL------GEGLTFYTRYNdr--ygPKYQNLIG 229
gi 198417343 512 YFTDSTdlKTLKTynngKGYHGFESMDektlA-VtKELI-----NYAQD-NSAPQLTNLDFFVPNN------SKYQSLIG 578
                        250
                 ....*....|.
2XID_A       314 TQWHPEDLVDI 324
gi 75424181  565 TECHPDDLVDV 575
gi 75397896  580 TQWHPEDLVDI 590
gi 122250731 350 TQYHPESLVDI 360
gi 75442359  230 SHVIPKKDDTP 240
gi 122541019 232 SHVIPKKDNIP 242
gi 75380721  237 SIIVPEEPQND 247
5DCQ_D       202 STLIPKEPLKP 212
gi 501966549 230 SIIVPEEPQND 240
gi 198417343 579 TEYHPDDLVDV 589
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