Conserved Protein Domain Family
TED

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pfam08341: TED 
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Thioester domain
This domain is found near the N-terminus of a variety of bacterial surface proteins and pili. This domain contains an unusual covalent ester bond between a conserved cysteine and glutamine residue.
Statistics
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PSSM-Id: 311998
View PSSM: pfam08341
Aligned: 26 rows
Threshold Bit Score: 171.773
Threshold Setting Gi: 501966549
Created: 26-Jul-2016
Updated: 4-Aug-2016
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2XI9_A       124 SVEAYNDFEEFSVltt---qnYAKFYYA-KNKNgSS----Q--VVYCFNADLKSPPDSEDGGKTxtpdft---tgevkYT 190
gi 75424181  371 SVEAYNDFMDEEVlsg--ftpYGKFYYA-TNKDkSS----Q--VVYCFNADLHSPPDSYDSGETinpdts--tmkevkYT 439
gi 122250731 155 SFEAYNDFSEYEIltt---qnYAKFYYA-KNQNgSK----Q--VVYCFNADLHSPPDSYDYGDNiepdia--tgrivkYT 222
gi 75407339   35 LYYGWNDGTRQSS--------PYFLYVSpKNAPkRElkdeY--VVYCFNKKLYWPDQWESIYSNfndirsp-yndlpvYE 103
gi 75442359   34 KYYGWNDGTRRDS--------PFFLYVSpQNDPkRElkdeC--IVYCFNRDKQWPETW-GVNRTfsqvqsevtfklplYE 102
gi 122541019  35 LYYGWNDGTRHNS--------PFFLYVTpENNPtRStddkY--VVYCFNRDREWPENW-DASRNfndvqndmvfklplYE 103
gi 560298645 373 SVTAFNDFEEIGYlsd--fnnYGKFYYA-KNTNgTS----Q--VVYCFNADLHSPPDSYDHGANidpdvs--eskeikYT 441
5DCQ_D         2 lYYGWNDGTRQSS--------PYFLYVSpKNAPkRElkdeY--VVYCFNKKLYWPDQWESIYSNfndirsp-yndlpvYE 70
gi 501966549  37 QYYGWSDGSSSY---------PSALYVTpVGDTtKK----IaiPVYCFDYKFQEPLAWKEITQPshl---------ivYD 94
gi 198417343 383 SVEAYSDMQDSNYinpetftpYGKFYYA-KNKDkSS----Q--VVYCFNADLHSPPESEDGGGTidpdis--tmkevkYT 453
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2XI9_A       191 HIAG--RDLFKYTVKPRDTDPd------TFLKH---IKKVIEKGYREKG--QAIEy-sGLTETQLRAATQLAIYYFTDSA 256
gi 75424181  440 HTAG--SDLFKYALRPRDTNPe------DFLKH---IKKVIEKGYKKKG--DSYN---GLTETQFRAATQLAIYYFTDSA 503
gi 122250731 223 QVKG--VDLLKYTVNARTSNSs------QFLTW---IKKVIFKGYKGEG--DNIPs--GLTPTQFRAATQLAIYYFTNSA 287
gi 75407339  104 KKLGydGIFKQYAPDYKKDIS-------DIASA---LVAVLSNGYPTNK--SQLStsyHLNNDSSRKVTQLAIWYFSDSL 171
gi 75442359  103 KKKGsdEVFKNNAPRFRGTVK-------NVTAA---LVAVLKSGYPTVK--Si----nHLDAEKSRKVTQLAIWYFSDSE 166
gi 122541019 104 RKDGsdEVFKKNAPHFRGTVK-------NVTAA---LVAVLESGYPTVK--Ni----gQLDAEKGRKVTQLAIWFFSDNQ 167
gi 560298645 442 HVSGy--DLYKYAVTPRDKDAd------LFLKH---IKKILDKGYKKKG--DTYk---TLTEAQFRAATQLAIYYYTDSA 505
5DCQ_D        71 KKLGydGIFKQYAPDYKKDIS-------DIASA---LVAVLSNGYPTNK--SQLStsyHLNNDSSRKVTQLAIWYFSDSL 138
gi 501966549  95 KYDGknLMAALVEKPNMVSYEtktklqtLLKTKsnlITAILSRGYPNKSffDKYk---KLTDEDKRRVTQCALWYHTDNi 171
gi 198417343 454 HTAG--SDLFKYALRPRDTNPe------DFLKH---IKKVIEKGYNKKG--DSYN---GLTETQFRAATQLAIYYFTDST 517
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2XI9_A       257 e----lDKDKLKDYHGFGDXNdstlA-VAKILV-----EYAQD-SNPPQLTDLDFFIPNN------NKYQSLIGTQWHPE 319
gi 75424181  504 dlktlkTYNNGKGYHGFESMDektlA-VTKELI-----TYAQN-GSAPQLTNLDFFVPNN------SKDQSLIGTECHPD 570
gi 122250731 288 dletlkTYDNNKGYHGFEDMNeatlK-VTKDLV-----AYALNnESANDLPDLDFLIPNN------NSYQSLVGTQYHPE 355
gi 75407339  172 t----kEYLKDTGGYNLNDME----KkALDFLIsk--gEDSKL-KSEQSNYSLDIYVYQSgghdhmKDYQNLLGSTLIPK 240
gi 75442359  167 nd--pdTYLQPS--EKLTQEE----KtAFNSLVee-gkKAGET-LSSTGDYTLDIYITTDkny-aqKQYQNLLGSHVIPK 235
gi 122541019 168 dn--pdDYLQSS--EKLSEQE----KsAFKSLVek-gkKAGES-PLSNGSYTLDIYITTNtkytthKLYQNLLGSHVIPK 237
gi 560298645 506 dlttlkTYNDNKGYHGFDKLDdatlA-VVHELI-----TYAED-VTLPMTQNLDFFVPNS------SRYQALIGTQYHPN 572
5DCQ_D       139 t----kEYLKDTGGYNLNDME----KkALDFLIsk--gEDSKL-KSEQSNYSLDIYVYQSgghdhmKDYQNLLGSTLIPK 207
gi 501966549 172 se--qdLITKHLDGDSGEKSQ------ALKELIgvvknTSNEL------GEGLTFYTRYNdr--ygPKYQNLIGSIIVPE 235
gi 198417343 518 dlktlkTYNNGKGYHGFESMDektlA-VTKELI-----NYAQD-NSAPQLTNLDFFVPNN------SKYQSLIGTEYHPD 584

                 ....*
2XI9_A       320 DLVDI 324
gi 75424181  571 DLVDV 575
gi 122250731 356 SLVDI 360
gi 75407339  241 EPLKP 245
gi 75442359  236 KDDTP 240
gi 122541019 238 KDNIP 242
gi 560298645 573 ELIDV 577
5DCQ_D       208 EPLKP 212
gi 501966549 236 EPQND 240
gi 198417343 585 DLVDV 589
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