Conserved Protein Domain Family
DUF1727

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pfam08353: DUF1727 
Domain of unknown function (DUF1727)
This domain of unknown function is found at the C-terminus of bacterial proteins which include UDP-N-acetylmuramyl tripeptide synthase and the related Mur ligase.
Statistics
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PSSM-Id: 337018
View PSSM: pfam08353
Aligned: 204 rows
Threshold Bit Score: 79.8317
Threshold Setting Gi: 752826762
Created: 27-Mar-2017
Updated: 23-May-2017
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81671274  321 NPVGLNETIRAVNDLKLQGQcstTLLVLN---DRIADGTDVSWIWDVDTEPLVAS-GGTFVVSGDR-LYDMALRLQYSQE 395
gi 524118637 322 NATTFNQSLLFVKRNKELKT---LIIGWRe-iSRRYNFDDLSWLYDIEFELLNNDeIDKIVCIGPQ-AYDIATRLKYADI 396
gi 503885902 323 NSIAYDTNLRYVRSTEDPCT---VVIIVDa-vSRKYYTSETSWLWDIDFGRLNCShVQKILLCGQY-ASDLAVRFSFTDV 397
gi 524535439 322 NSIAYDTNLRYIRGEQSPCT---VLVIVDa-vSRKYFTSETSWLWDIDFDQLNCPqVQRVILSGRY-CNDLAERFSFTAL 396
gi 524500838 322 NSVSYDQSLTLAANDKQGCD---VLIIVDa-iSRKYFTSDVSWLWDIDFELLSSKnVGEIVLAGLY-SADLQTRFSFTGI 396
gi 524541076 322 NSVSYDQSLRYISQQKEPHA---VSVTVDa-iSRKYFTSDTSWLWDIDFDLLDTPeTEHIYLCGRY-ADDLAVRFSYTGI 396
gi 524613382 327 NPETMQNALDTIARDNTKKA---IFMGLYeikDFPPAYTNTFYFFDCDFKKCVSDlVEEYVCFSKTvAYDTANRMIYAGA 403
gi 524252698 328 NPETLQSALNYISSDSNKKI---FVMGLSevkDFYPYYSNTFYTFDCDFKGIENSnVDKYICFSEAvAYDSANRLIYAGI 404
gi 503145844 325 NPDTLQSALNIMASDQEEKM---VCFGFYavsDFIPFYTNTFYSFDCDFKPLAESnVEKYFCFSQNvCYDTANRLIYEGV 401
gi 504122769 325 NPDTLQSALNIMASDTNEKM---VALGLYvvnDFVPHYINTFYAFDCDFKPLIESkVERYLCFSEHvSYDTANRLIYEGV 401
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....
gi 81671274  396 nliqpsqgeepwdgHTSRLIL------EENLEKAVQialelTPAEETLHIIPTY 443
gi 524118637 397 --------------DESHIVVip---lIDEACKFIK-----AKTKGNIYGILnf 428
gi 503885902 398 --------------PQEKIELhp---dITEACNSLK-----AGGAEDVYVLTCF 429
gi 524535439 397 --------------PAEKWSVqp---dIAAAAKELA-----ESGSEDVYVVTCf 428
gi 524500838 397 --------------EESKIKAfs---dIGEATEYLK-----TSSDRKLYVITCF 428
gi 524541076 397 --------------DPEKITVte---sIPESLDAIK-----KSGHGRLYAVtcf 428
gi 524613382 404 --------------KENKIKVydveddFDLIFEDLD-----KLKTDNIYIItgm 438
gi 524252698 405 --------------PKEKIEIlpt-enVEEVLKKLD-----EYDTNNIYLItll 438
gi 503145844 402 --------------ESSKIVIkdt-ddIKTIFEEIE-----KADTSNIYLItwl 435
gi 504122769 402 --------------NKEAITImds-ddIKTIFSEID-----KAKTDNIYLItwi 435
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