Conserved Protein Domain Family
GbpC

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pfam08363: GbpC 
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Glucan-binding protein C
This domain is found in the Streptococcus Glucan-binding protein C (GbpC) and also in surface protein antigen (Spa)-family proteins which show sequence similarity to GbpC.
Statistics
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PSSM-Id: 312014
View PSSM: pfam08363
Aligned: 10 rows
Threshold Bit Score: 286.369
Threshold Setting Gi: 527769915
Created: 22-Jul-2016
Updated: 4-Aug-2016
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3IPK_A        107 EKHKNE------DGNLTEpsAQNLVYDL-EPNANLSLTTDG---------KflkasavddAFSKSTskA--KYDQKILQl 168
gi 81588294   166 EQYKKEvaqglaSGRVEK--AQGLVFIN-EPEAKLSIEGVN---------Q---------YLTKEArqK--HATEDILQq 222
gi 81722472   256 NKHKND------KGYVNEaiSKDLVFDS----------------------S---------IVTKDT---------KIDKi 289
gi 114245     256 NKHKNE------NGYVAKpvNKTLIFD-----------------------R---------EATKNS---------KVVSv 288
gi 502485148  154 ERKKNE------DGYMTKpyPQLLTFKS-EPNATLTVSG-----------K---------KYTRSE------FSSEV--- 197
gi 502483079  154 ERKKNE------DGYMKEpaSQSLTFQS-EPNATMSFPNGD---------Q---------TYTQSE--W--Kty------ 198
gi 321279224  108 ESKKKQ------DGYLSEprSQSLNFKS-EPNAIRTIDSSV---------H---------QYGQQE--L--DA------- 151
gi 500811530  491 EKNKNQ------DGYLSKpsAQSLVYDS-EPNAQLSLTTNGkmlkasavdE---------AFSHDT--A--QYSKKILQp 550
gi 26007028   492 EKHKNE------DGNLTEpsAQNLVYDL-EPNANLSLTTDGkflkasavdD---------AFSKSTskA--KYDQKILQl 553
gi 527769915  370 EISKGE------EGYISEalAQALNLNNgEPQAQHGAITRNp-------dQ---------IISTGD--AllGGYSRILDs 425
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3IPK_A        169 ---dDLDITNLEQSNDVASSMElygnfgdkagws--------ttvsnnsqvkwGSVLLERGQSATATYTNLQNSYYNGKK 237
gi 81588294   223 yntdNYTASDFTQANPYDPKED-------------------------------TWFKMKVGDQISVTYDNIVNSKYNDKK 271
gi 81722472   290 tggkFIKASDFNKVNQGQSKDIftklskdmngkatgnfqsskvaavefgpkggYAVLLEKNKPVNVTYTGL-NASYLDRK 368
gi 114245     289 kaaeYIDAKKL--TDKHKDKKLlismlsvdssglttk-dskkahfyynngaggTLVVLHKNQPVTITYGNL-NASYLGKK 364
gi 502485148  198 ------RSWNLG-TEPWRyayfdaln--------------------ngqpnsaARVMLEKDKPFVATYTNLTNSSYNGKK 250
gi 502483079  199 --fdNNISSQLG-SNPAYGANDfnyins-------------------vanadeTRVILHKDQPLKVQYTNLQNSYFNGKK 256
gi 321279224  152 ----LVKSWGISPTNPDRKKSTaysyfna-----------------insnntyAKLVLEKDKPVDVTYTGLKNSSFNGKK 210
gi 500811530  551 ---dNLNVSYLQQADDVTSSMElygnfgdkagwt--------ttvgnntevkfASVLLERGQSVTATYTNLEKSYYNGKK 619
gi 26007028   554 ---dDLDITNLEQSNDVASSMElygnfgdkagws--------ttvsnnsqvkwGSVLLERGQSATATYTNLQNSYYNGKK 622
gi 527769915  426 tgffVYD-------------------------------------------------MFKTGETLSFNYQNLQHARFDGKK 456
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3IPK_A        238 ISKIVYKYTVDPKS--Kf-QgQKVWLGIFTDPTLGVFASAYTGQVEKNTS-IFIKNEFTFYDEDGKPINFDn--ALL-SV 310
gi 81588294   272 ISKVKINYTLNSST--N--NeGSALVNLFHDPTKTIFIGAQTSNAGRNDK-ISVTMQIIFYDENGNEIDLSgnnAIM-SL 345
gi 81722472   369 ITKAEFIYELQSAP--S--QsGTLNAVFSNDPIITAFVGTKNANGKD----VKVRLTIKLYDANGKEVLPDkdhAFAyAL 440
gi 114245     365 IASAEFQYTVKATP--D--SkGRLNAFLHDDPVATIVYGINIDPRTKKAG-AEIEMLVRFFGEDGKEILPTkenPFVfSG 439
gi 502485148  251 ISKVEYTYTYKGSSgvN--VpDKLPVVLQQDPTVTIWYNDFFG------D-ARINMKVKFYDEDGNVIDPTg--SLL-NF 318
gi 502483079  257 ISKVEYTYTLKNTGl-P--GvNSMPALIEKDPTVTLWYLNFYGE-------ADINMKVKFYDEDGNVIDPTg--ALL-NF 323
gi 321279224  211 ISKVVYTYTLKETGf-N--DgTKMTMFASSDPTVTAWYNDYF------TS-TNINVKVKFYDEEGQLMNLTg--GLV-NF 277
gi 500811530  620 ISKVVFKYTLDSDS--KfkNvDKAWLGVFTDPTLGVFASAYTGQEEKDTS-IFIKNEFTFYDENDQPINFDn--ALL-SV 693
gi 26007028   623 ISKIVYKYTVDPKSkfQ--G-QKVWLGIFTDPTLGVFASAYTGQVEKNTS-IFIKNEFTFYDEDGKPINFDn--ALL-SV 695
gi 527769915  457 ISRVTYDITNLVSP--A--GtNAVKLVVPNDPTEGFIAYRNDGNGDWRTDkMEFRVVAKYYLEDGSQVTFSkekPGVfTH 532
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3IPK_A        311 ASLNREh-----------NSIEMAKDY--SGKFVKISGSSIG-EKNgMIYATDTLNFK--QgeGGSRWTMykns-qagSG 373
gi 81588294   346 SSLNHWttk-------ygDHVEKVNLG--DNEFVKIPGSSVDlHGN-EIYSAKDNQYK--A--NGATFNGdg-----aDG 406
gi 81722472   441 SSLNSSlgtn-----ysvEHAEFVSDFgsKNEFKYINGSYVKkQADgKFYSTEDLDYG--TgpSGLKN----------SD 503
gi 114245     440 ASLNSRge---------nITYEFVK-VgnTDTVHEINGSKVArHGN-KVYSKTDIDVG--T--NGISI----------SD 494
gi 502485148  319 SSLNRGngsg----vvdkDAIEKVAYF--NGEYVPISGSSISvHADgSAYSDTNNAER--A--KGAKFNT--------DE 380
gi 502483079  324 SSLNHGigtsstpkvdgqDTVEKVRSF--NGEFIEISGSSITkQPDgGAYASNNNEQK--S--AGSRFNT--------SE 389
gi 321279224  278 SSLNRGngsg----aidkDAIESVRNF--NGRYIPISGSSIKiHENnSAYADSSNAEK--S--LGARWNT--------SE 339
gi 500811530  694 ASLNREn-----------NSIEMAKDY--SGTFVKISGSSVG-EKDgKIYATETLNFKqgQ--GGSRWTMykns-qpgSG 756
gi 26007028   696 ASLNREn-----------NSIEMAKDY--TGKFVKISGSSIG-EKNgMIYATDTLNFR--QgqGGARWTMytrasepgSG 759
gi 527769915  533 SSLNHNd-----------IGLEYVKDS--SGKFVPINGSTVQvTNEgLARSLGSN--------RASDLNLp-------EE 584
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3IPK_A        374 WD------SSDAPNSWYGAGAI-KMS-GPNNYVTVGATS--AtnvmpvsdmpvvpgkdntdGk--------------kP- 428
gi 81588294   407 WDavnadgTPRAATAYYGAGAM-TYK-GEPFTFTVGGND--Q-------------------Nl--------------pT- 448
gi 81722472   504 WD------AVGHKNAYYGSGVGlARE-GGRISFSFGMTT--K-------------------Gkvn-----------lsG- 543
gi 114245     495 WE------AVQGK-EYIGATV--IST-PNRIKFTFGNEI--V-------------------Nn--------------pGy 529
gi 502485148  381 WD------TPDSPNAWYGAIVG-RVI-GPEISLDMASHK--S-------------------G------------------ 413
gi 502483079  390 WD------SDTNSNAWYGAIVG-KVT-NPEININIGASK--R-------------------G------------------ 422
gi 321279224  340 WD------TTSSPNNWYGAIVG-EIT-QSEISFNMASSK--S-------------------G------------------ 372
gi 500811530  757 WD------SSDAPNSWYGAGAI-SMS-GPTNHVTVGAIS--Atqvvpsd-----pvmavatGk--------------rP- 806
gi 26007028   760 WD------SSDAPNSWYGAGAI-RMS-GPNNSVTLGAIS--S-------------------TlvvpadptmaietgkkP- 809
gi 527769915  585 WD------TTSSRYAYKGAIVS-TVTsGNTYTVTFGQGDmpQ-------------------Nv--------------gL- 623
                         410
                  ....*....|
3IPK_A        429 ---NIWYSLN 435
gi 81588294   449 ---TIWFATN 455
gi 81722472   544 ---AQWFAFs 550
gi 114245     530 dgnSMWFAFN 539
gi 502485148  414 ---VVWFALN 420
gi 502483079  423 ---VVWFALN 429
gi 321279224  373 ---NIWFAFN 379
gi 500811530  807 ---NIWYSLN 813
gi 26007028   810 ---NIWYSLN 816
gi 527769915  624 ---SYWFALN 630
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