3IPK


Conserved Protein Domain Family
GbpC

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pfam08363: GbpC 
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Glucan-binding protein C
This domain is found in the Streptococcus Glucan-binding protein C (GbpC) and also in surface protein antigen (Spa)-family proteins which show sequence similarity to GbpC.
Statistics
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PSSM-Id: 337022
View PSSM: pfam08363
Aligned: 8 rows
Threshold Bit Score: 287.176
Threshold Setting Gi: 114245
Created: 26-Mar-2017
Updated: 23-May-2017
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3IPK_A         107 EKHKNE------DGNLTEpsAQNLVYDL-EPNANLSLTTDgkflkasavD---------DAFSKSTSKAKYDQKILQl-- 168
gi 81588294    166 EQYKKEvaqglaSGRVEK--AQGLVFIN-EPEAKLSIEGV---------N---------QYLTKEARQKHATEDILQqyn 224
gi 81722472    256 NKHKND------KGYVNEaiSKDLVFDS-------------------------------SIVTKDT-------KIDKitg 291
gi 114245      256 NKHKNE------NGYVAKpvNKTLIFD--------------------------------REATKNS-------KVVSvka 290
gi 502483079   154 ERKKNE------DGYMKEpaSQSLTFQS-EPNATMSFPNG---------D---------QTYTQSEWKTYFDNNI----- 203
gi 502485148   154 ERKKNE------DGYMTKpyPQLLTFKS-EPNATLTVSG--------------------KKYTRSE----FSSEV----- 197
gi 26007028    492 EKHKNE------DGNLTEpsAQNLVYDL-EPNANLSLTTD---------GkflkasavdDAFSKSTSKAKYDQKILQl-- 553
gi 1160921782  370 EISKGE------EGYISEalAQALNLNNgEPQAQHGAITR---------Np-------nQIISTGDAMLGGYSRILDstg 427
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3IPK_A         169 -dDLDITNLEqSNDVASSMElygnfgdkagws--------ttvsnnsqvkwGSVLLERGQSATATYTNLQNSYYNGKKIS 239
gi 81588294    225 tdNYTASDFTqANPYDPKED-------------------------------TWFKMKVGDQISVTYDNIVNSKYNDKKIS 273
gi 81722472    292 gkFIKASDFNkVNQGQSKDIftklskdmngkatgnfqsskvaavefgpkggYAVLLEKNKPVNVTYTGL-NASYLDRKIT 370
gi 114245      291 aeYIDAKKL--TDKHKDKKLlismlsvdssglttk-dskkahfyynngaggTLVVLHKNQPVTITYGNL-NASYLGKKIA 366
gi 502483079   204 -----SSQLG-SNPAYGANDfnyins-------------------vanadeTRVILHKDQPLKVQYTNLQNSYFNGKKIS 258
gi 502485148   198 ----RSWNLG-TEPWRyayfdaln--------------------ngqpnsaARVMLEKDKPFVATYTNLTNSSYNGKKIS 252
gi 26007028    554 -dDLDITNLEqSNDVASSMElygnfgdkagws--------ttvsnnsqvkwGSVLLERGQSATATYTNLQNSYYNGKKIS 624
gi 1160921782  428 ffVYDS-------------------------------------------------FKTGETLSFNYQNLQNARFDGKKIS 458
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3IPK_A         240 KIVYKYTVDPKS--KfQgQKVWLGIFTDPTLGVFASAYTGQVEKNTS-IFIKNEFTFYDEDGKPINFDn--ALL-SVASL 313
gi 81588294    274 KVKINYTLNSST--N-NeGSALVNLFHDPTKTIFIGAQTSNAGRNDK-ISVTMQIIFYDENGNEIDLSgnnAIM-SLSSL 348
gi 81722472    371 KAEFIYELQSAP--S-QsGTLNAVFSNDPIITAFVGTKNANGKD----VKVRLTIKLYDANGKEVLPDkdhAFAyALSSL 443
gi 114245      367 SAEFQYTVKATP--D-SkGRLNAFLHDDPVATIVYGINIDPRTKKAG-AEIEMLVRFFGEDGKEILPTkenPFVfSGASL 442
gi 502483079   259 KVEYTYTLKNTGl-P-GvNSMPALIEKDPTVTLWYLNFYGE-------ADINMKVKFYDEDGNVIDPTg--ALL-NFSSL 326
gi 502485148   253 KVEYTYTYKGSSgvN-VpDKLPVVLQQDPTVTIWYNDFFG------D-ARINMKVKFYDEDGNVIDPTg--SLL-NFSSL 321
gi 26007028    625 KIVYKYTVDPKSkfQ-G-QKVWLGIFTDPTLGVFASAYTGQVEKNTS-IFIKNEFTFYDEDGKPINFDn--ALL-SVASL 698
gi 1160921782  459 RVTYDITNLVSP--A-GtNAVKLVVPNDPTEGFIAYRNDGNGDWRTDkMEFRVVAKYFLEDGSQVTFSkekPGVfTHSSL 535
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3IPK_A         314 NREh-----------NSIEMAKDY--SGKFVKISGSSIG-EKNgMIYATDTLNFKQgeGGSRWTMykns-qagSGWD--- 375
gi 81588294    349 NHWttk-------ygDHVEKVNLG--DNEFVKIPGSSVDlHGN-EIYSAKDNQYKA--NGATFNGdg-----aDGWDavn 411
gi 81722472    444 NSSlgtn-----ysvEHAEFVSDFgsKNEFKYINGSYVKkQADgKFYSTEDLDYGTgpSGLKN----------SDWD--- 505
gi 114245      443 NSRge---------nITYEFVK-VgnTDTVHEINGSKVArHGN-KVYSKTDIDVGT--NGISI----------SDWE--- 496
gi 502483079   327 NHGigtsstpkvdgqDTVEKVRSF--NGEFIEISGSSITkQPDgGAYASNNNEQKS--AGSRFNT--------SEWD--- 391
gi 502485148   322 NRGngsg----vvdkDAIEKVAYF--NGEYVPISGSSISvHADgSAYSDTNNAERA--KGAKFNT--------DEWD--- 382
gi 26007028    699 NREn-----------NSIEMAKDY--TGKFVKISGSSIG-EKNgMIYATDTLNFRQgqGGARWTMytrasepgSGWD--- 761
gi 1160921782  536 NHNd-----------IGLEYVKDS--SGKFVPINGSTVQvTNEgLARSLGSN------RASDLNLp-------EEWD--- 586
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3IPK_A         376 ---SSDAPNSWYGAGAI-KMS-GPNNYVTVGAtsatnvmpvsdmpvvpgkdNT--DGk--------------kP----NI 430
gi 81588294    412 adgTPRAATAYYGAGAM-TYK-GEPFTFTVGG-------------------ND--QNl--------------pT----TI 450
gi 81722472    506 ---AVGHKNAYYGSGVGlARE-GGRISFSFGM-------------------TT--KGkvn-----------lsG----AQ 545
gi 114245      497 ---AVQGK-EYIGATV--IST-PNRIKFTFGN-------------------EI--VNn--------------pGydgnSM 534
gi 502483079   392 ---SDTNSNAWYGAIVG-KVT-NPEININIGA-------------------SK--RG---------------------VV 424
gi 502485148   383 ---TPDSPNAWYGAIVG-RVI-GPEISLDMAS-------------------HK--SG---------------------VV 415
gi 26007028    762 ---SSDAPNSWYGAGAI-RMS-GPNNSVTLGA-------------------IS--STlvvpadptmaietgkkP----NI 811
gi 1160921782  587 ---TTSSRYAYKGAIVS-TVTsGNTYTVTFGQ-------------------GDmpQNv--------------gL----SY 625

                   ....*
3IPK_A         431 WYSLN 435
gi 81588294    451 WFATN 455
gi 81722472    546 WFAFs 550
gi 114245      535 WFAFN 539
gi 502483079   425 WFALN 429
gi 502485148   416 WFALN 420
gi 26007028    812 WYSLN 816
gi 1160921782  626 WFALN 630
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