Conserved Protein Domain Family
NIT

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pfam08376: NIT 
Nitrate and nitrite sensing
The nitrate- and nitrite sensing domain (NIT) is found in receptor components of signal transducing pathways in bacteria which control gene expression, cellular motility and enzyme activity in response to nitrate and nitrite concentrations. The NIT domain is predicted to be all alpha-helical in structure.
Statistics
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PSSM-Id: 337029
View PSSM: pfam08376
Aligned: 370 rows
Threshold Bit Score: 44.3922
Threshold Setting Gi: 503091326
Created: 27-Mar-2017
Updated: 23-May-2017
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75431773    59 AHNFAVERGLTAGFIA-S--KGr-SG------------------KDK-LLSQRQKSDQAEQILRsftply---------- 105
gi 123733583   91 gNELGKERMLVAAYIAdnpnP-------------------------------TRRSNDRAVALQeqqkivdqelndvrag 139
gi 918028072   80 AHNLEAERDLSARFVAqGr-GS--TG------------------KAR-LQEQYRAVDQVAKKARdridliigsn------ 131
gi 502896254   51 THELQTERDRAAWNAAlGr-PE--KA------------------TAA-VVTQTTAVNKAAAEVRkiaasvr--------- 99
gi 268311003   51 aqefaaeRDMAAGYISaGr-SG--RG------------------ADE-LQAQYRKTDAAADQVRqvalgid--------- 99
gi 402799090   46 ANQLGRERTASAVYISdnsdP-------------------------------TRRSDALRQELDeqrdasrdlqstliar 94
gi 908668360   51 ANQLGHERSASAVYISdnadP-------------------------------ARRSDELRQRMEeerdasrdlqqtltar 99
gi 502652282   93 THELAEERDHTAWFIAlGrp----------------------arEAEaVRTRMNAVDAAVTHVRdsgtllr--------- 141
gi 918028071   51 SHEMAEERDLTAWYIAdR--RRpaRL------------------TR--VKQQREVVNQASAQVQksiesld--------- 99
gi 365808278   36 SHSLADERADMAAYVAtGr-GA--RKppaaahgntvgrgvseeeRAR-VDRQTAEVT-ADAAVLdtgdstdl-------- 102
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75431773   106 ------ldkqliNALLSDIIQQLNYKSTIRSQVDnlSIQ-NSPFIYYSTLNQLSLDSISIIIG-NIDDQFIRNEMLGLSA 177
gi 123733583  140 anelgtpsdplvKERLDIMLDSLEKLNGVREEVTstRVTmLPAVTKYRQIISTLTDFVETLANaTNTSSELRESVRALSA 219
gi 918028072  132 ---adegfgergKTELAQMRSRIDELDSVRKTAVgtQLPaQPTIAMYSRTIADLLALHDEIIQ-GVADQELAGSATAFGA 207
gi 502896254  100 -----adaepraADRIDHVISRLDTLESLRKQAVsgSLLpGAVMTQYTLILDELLELHDELSV-IAGDERLAAMSTSLGA 173
gi 268311003  100 -----dsfsaeaVRDARSVLNRLDTIGSLRSTATqsRAPaLVVVEKYSEVINELIGVLDGVAQ-GVADEQLAETTRAMAA 173
gi 402799090   95 lddmgemdgdlaQGRLSTMRSQLSTVDDLRSEVDesRITvLPVVTKYRTIIRSLADFNQTIADeTD-DTDLRESVRALTA 173
gi 908668360  100 lddmgevdtetaSSRLSSMRSQLSTLDALRTEVDetRITvLPVVTKYRTITRSLAEFNQTMADgTG-DTDLRESVRTLTA 178
gi 502652282  142 -----kavtgrtRDEVDTVITRLDDLGPLRDQALksTLLpDAAIDAYSLVIADLLSLHDELGK-GSADDVLFGQALTLDA 215
gi 918028071  100 -----rgqasrvLTETAQVNRWLKGLPGLR-RPMegSVLpRAALSIYSRMITDFITLHDDLGR-SGGDERLIGDALALGA 172
gi 365808278  103 ------------irvtgdlSSALASLPKVRQGALagPGDaKAAFDAYTPLIDALDAVGGALAR-ALPSRASDADTAAGPA 169
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75431773   178 LLQVKEEAGKVRGALNGAFAGkrssLDKFADINSYISTESlAI-RQAQSVLSnrFTKTLNTTIeSKTWKQVSDIQASyls 256
gi 123733583  220 LGRARDDQSYEAALMVHSLIRdsmsGGVQDSIESTQARYNnEIrN-FRNSATpaQEALLDENYgGLDVSRLGTMRLRall 298
gi 918028072  208 LSRAKEQASRERANLAIALADrtftSEGLNAMLAARAQRD-SElAAFRSDASvtQRQLYDDTVsSQKKDRAESMRARalv 286
gi 502896254  174 LATAKEAMSVQRGLLTTVLPAgrfdQEQYRQFLGALAIEE-RAlSTFRKHASreERAEYDRTVsGAGVEDAAFLRALvld 252
gi 268311003  174 LSRAKEQVSRQRALLTIGAVQgrlsVEELAALEASRDREN-SElNAFLQTATlpQRQMFEDTVvGPQIDRARVIRQQaia 252
gi 402799090  174 LSNARDQLSYETALMGHSLTRnsmtGGISEAIDSSRARYEnEIsN-FVQAAHpdQRAIFDEHFtGLEVSQVSTMRMRvmy 252
gi 908668360  179 LSTARDQLSYETALMGHSLARntmtGGIAEAIDSARARYEsEIsN-FVQAASeeQRQIFDDNFtGLEVSQVSTMRMRvmy 257
gi 502652282  216 LARAKEAASLQRALLAVVLVAgrfeQEQMERFLGALSSER-NErRTFAAEAGseRRRLFDETVnGRTADRAEFLRELvll 294
gi 918028071  173 LTRAKEQVAVQRGILLVGLQErkfdFDDPAQFLGAHQSQLsEV-AAFRATAAsgDIKRFDEAVsGEKIDRADSITALvrs 251
gi 365808278  170 LATAVEDASATRGQLVAALTAggtsAALAGGAQQSRTGEL-AAlADFNAAATqqARTRYAQTVtGADVATAESYLHRlta 248
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 75431773   257 qkdn--------lnalngP--------NA------NEWFSLATQRIGLIKAITDNISAELN 295
gi 123733583  299 radegqpltgitdgddadS------------------YQQTALSALDTLAKVESSLARMVR 341
gi 918028072  287 lave--------gaplvrIdvsrtgagDQ------TTWFDASSDTIERMRAVEKRIADTLI 333
gi 502896254  253 rvaagfs--lhqldrtarD--------DA------RRWFDAMTQPINSIRTVEGKLAASIV 297
gi 268311003  253 sana--------tggrlpR--------SLrtaeaiETLTASMTAMVDQMRTAERNLGEELL 297
gi 402799090  253 radrgddltgvtandgpaD------------------YQEIADVALERLETVETGLAEGIA 295
gi 908668360  258 radrgddltgvtandgpeD------------------YREIADVALGRLQTVEEGIAEGIA 300
gi 502652282  295 raasgaslk----------------gldlaeeddarqWYDAATVTIDRMRDVEQRHAQDIV 339
gi 918028071  252 rmrefk----------------------plpvrglnNWFSSSTATVDGMRAVERGLSAAVV 290
gi 365808278  249 kgylta----------------------adnrlrtadVDAALAARVDRMRAVQSSLAgadt 287
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