Conserved Protein Domain Family
ITAM_Cys-rich

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pfam10538: ITAM_Cys-rich 
Immunoreceptor tyrosine-based activation motif
Signal transduction by T and B cell antigen receptors and certain receptors for Ig Fc regions involves a conserved sequence motif, termed an immunoreceptor tyrosine-based activation motif (ITAM). It is also found in the cytoplasmic domain of apoptosis receptor.
Statistics
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PSSM-Id: 119058
View PSSM: pfam10538
Aligned: 6 rows
Threshold Bit Score: 45.52
Threshold Setting Gi: 156567220
Created: 27-Jul-2016
Updated: 4-Aug-2016
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                          10        20
                  ....*....|....*....|....
gi 81981021   219 KRGLYRTLSMFRYKSKCYVGLVWC 242
gi 731115     621 MQGCYRTLSLFRYRSRFFVGLVWC 644
gi 81980470   617 KRGCHRALSIFRYRSRCFVGLVWC 640
gi 81969130    54 RKGCYRTLGVFRYKSRCYVGLVWC 77
gi 75569298   609 GPGCYRTLNLFRYKSRCYILTMWT 632
gi 156567220  600 HSSLYKKLCVFRYTNRCYIFTVWV 623
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