Conserved Protein Domain Family
CYTL1

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pfam15153: CYTL1 
Cytokine-like protein 1
The function of this family of proteins, CYTL1, has not, as yet, been determined. However it is thought to be a secretory protein expressed in CD34+ haemopoietic cells. This family of proteins is found in eukaryotes. Proteins in this family are typically between 134 and 145 amino acids in length. There are two conserved sequence motifs: PPTCYSR and DDC.
Statistics
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PSSM-Id: 317558
View PSSM: pfam15153
Aligned: 11 rows
Threshold Bit Score: 183.357
Threshold Setting Gi: 50747230
Created: 29-Jul-2016
Updated: 4-Aug-2016
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 573883122   8 FIVLCSLI---FLA-NCAPPpTCYSRVLSYSKEIMKFMETLQKSYRTKSCMEALPKMYLDVHNSCIMPKLRDFlyvlenL 83
gi 557018485   7 VAVLFTVL---AIA-NAVPP-TCYSRVLTLSEEIMDSVKFLQRFKRTSPCVDVLPKLYLDVHNSCIMSKLRDHlyilqnL 81
gi 597758068   6 lllllslA---RPA-RSAPP-TCYSRMLDLSKEIMEVLERIHRFPRTKECAQVLPKMFLDIHNSCITAKLRDFlyvvenL 80
gi 348557172   7 ALLLLLLLa-gPPA-SAAPP-TCYSRMLGLSQEITRDFQLLQAVEPE-VCVRYLPRLYLDIHNYCVLAKLRDF------V 76
gi 38649283    5 LLLLVVVViawPLAvQSAPP-TCYSRMLTLSREIMADFQSLQASEPEDSCVRYLPRLYLDIHNYCVLAKLRDF------V 77
gi 76620378    8 LLLLLLLLaglPTT-RPTPP-TCYSRMLALSREITSDFQSLQATEPSEACVRYLPRLYLDIHNYCVLAKLRDF------V 79
gi 410920361   6 LLGLCCLL---RLS-GCAPP-TCYSRALGLSKEVMTLLDKIHTSERTKTCAEVLPTIFLDVHNSCVTSKLRDF------L 74
gi 348508110   8 LLCLSSLV---WLS-ECTPP-TCYSRALNLSKEIKTLLDKIHTFHRTKTCAEILPTIFLDVHNSCITTKLRDF------L 76
gi 301619434   7 LLALSLLF---LFA-FSAPP-TCYSRVFSLSKEITDSFQRIQKAAPPGPCLDALPTLYLDIHNSCVMTKLRTF------I 75
gi 50747230    2 LLSLFALLsaaLLA-RAAPP-TCYSRVLSLSKEITESFKELQTSKAKDPCVETLPRLYLDIHNYCVLTKLRDF------V 73
gi 831243307  23 LLLLLLAV---PPA-WPAPP-TCYSRMLSLSREVTNDFQRLLAAELQEPCVRHLPRLYLDIHNYCVLAKLRDF------V 91
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 573883122  84 ------TRPECRERPRILGLKRKIRSLYIIINKVCYRDLVFYTDDCDALVTGEST 132
gi 557018485  82 ------TPPKCRDFPRVTILKNKVRNLYTIMSKVCYRDVVYLSDDCDAMEHPPPT 130
gi 597758068  81 ------PVEACRERPRFVNLKRKVQKLYFIISQACYRDLVYLTDDCEALDTGYSR 129
gi 348557172  77 ------ASPQCWRVARVDALKDKVRKLYTIMNSFCRRDLVFLSDDCSALEYPVPV 125
gi 38649283   78 ------ASPQCWKMAEVDTLKDRVRKLYTIMNSFCRRDLVFLSDDCSALEDPIPE 126
gi 76620378   80 ------ASPHCWKLAQVDALKDKVRKLYTIMNSFCRRDLVFLTDDCNALEYPVLV 128
gi 410920361  75 yvvlnhPDQSCRKRPRMMLLKRKVQNLYTIITRLCYRDLVFFMDDCEAIDTGHGT 129
gi 348508110  77 yvvlnhPNQYCREKPRMVLLKRKIQNLYSIITRICYRDLVFFTDDCQAIDTGNTR 131
gi 301619434  76 ------SAPRCGRMPRVEALKKRVRNLYNIMNSICKRDLVFFTDDCEALEMPLSV 124
gi 50747230   74 ------AYPRCERVLEVSELKEKARSLYTIMISYCRRDLAFLTDDCNALESPIQS 122
gi 831243307  92 ------ASPQCWKMAQADALKEKVRKLYTITNVYCRRDLVFLSDDCSALEYPIPV 140
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