Conserved Protein Domain Family
DUF4579

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pfam15158: DUF4579 
Domain of unknown function (DUF4579)
This family of proteins is found in eukaryotes. Proteins in this family are typically between 192 and 239 amino acids in length. The human member of this family is C8orfK29.
Statistics
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PSSM-Id: 317562
View PSSM: pfam15158
Aligned: 8 rows
Threshold Bit Score: 223.457
Threshold Setting Gi: 156362474
Created: 29-Jul-2016
Updated: 4-Aug-2016
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973138802  18 QALNSKLKKNSYHPFVL-KRHnVLVMEYLHEDLWKGVLLLVASVVGNALYLSRDVKDFHQYAg---YLVFC--------- 84
gi 313215525  37 EEIFQRLTTNKFWPFHD-YGP-FFELEYTNPNYYKAVVQFILWTVVVVIRGISHAVNKDRLTwsdlHFFFY--------- 105
gi 260800295  21 DFLKKRLTKNPTYPFRE-VSPnNFAVEIRDWRLQFGYLTAIFGLV-------------TACSw---YFIFGyfdeyfflv 83
gi 514449420  32 RHLARRLKNNSFYPFTQ-QQPgVFVLEYYLDTLWKGTLLFVICLLLVSLDILRQAEKQVTWA----VLAYG--------- 97
gi 953862772  88 RHLAKRLKDNSFYPFTQ-QQPnVFVLEYYLDTLWKGTLLFVVCLLFVSFGFLSQVQNQETWG----FPAYG--------- 153
gi 156362474  17 AIFNRRLTANPHYPFERgTDKtKFILHLSSRRHIYSLFMFSTSVVILIFWSIFESAGQ--------FMLFP--------- 79
gi 821466435  35 RHLAKKLKKNPFYPFFR-QQAnVYVLEYYQDTLWKGLLLFLICIVLMSLGIFRKLQNQETWG----FPAYG--------- 100
gi 440904364  30 RSLARRLKNNSFYPFMQ-QQPnVFVLEYYLDTLWKGTLLFIVCILLISFGLVSEVQKQETWG----FPAYG--------- 95
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973138802  85 ----LCLAL------WLI------ASSSFRRKLVVDHTAGAYRFYIHGRLRHQGPLHQIYIRMRAQKSGQGRLLYKLILH 148
gi 313215525 106 ----LLIPT------WIIyklfdiIRYWDYRQLAIRKMQNTYEFKIGDTVTHEGDLSDIYIRIEALDGADGKLFYRLILN 175
gi 260800295  84 tvsaLVTCM------YLI------GCFRQPRKLFLNSESLEYQWYKGEDLVYRGHYHNVYLRLAGQSTG-SAIYYKLVIR 150
gi 514449420  98 ----MCVGL------WLL------ISSLPLRRLVLNHTRGMYHFSIQGRTVYQGPMHLVYVRLALNSDAKGRRFFRLVLC 161
gi 953862772 154 ----VGVGL------WLM------ISSLPRRRLVLNHTRGMYHFSIEGRTVCQGPMHLIYLRLALNSDGDAR-------G 210
gi 156362474  80 ----VLVSIisgllaWE---------SRGKRTCELDFKKKRYKVVASGHPVCGGEFHNVYIRLKAQKHGAGQMYYYVVFN 146
gi 821466435 101 ----VGIGL------WLT------ISSLPKRRLVLNHSRGMYHFSIHGRTVCQGPLHRIYIRLALRSDAYGRCFFQLVLC 164
gi 440904364  96 ----VGVGL------WLM------ISSLPRRRLVLNHARGVYHFSIQGRTVCQGPMHLVYVRLALNSDAYRRCFFQLVLC 159
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 973138802 149 GYK-----LEEQQLSGFCEKYELLEILGRRMASKLNINYFDYQDVSTRHLVNQWP 198
gi 313215525 176 GYN-----IEKYILTTMTDKKDDLDKIGRLIARRINLNYFDCNDISSKNVVRHIE 225
gi 260800295 151 GYK-----IEGQDLCRATKNREKLIKLARRLAAKLNLNFFDYEDSSSSHAIRHYc 200
gi 514449420 162 GHK-----LEPLVLVQLSERYEHMEYLGRHIARKLSINYFDYLVASYRHEIRHWP 211
gi 953862772 211 GPRsgggcANEGKDA-------QMEYLGRHIARKLNINYFDYLxTSYRHVVRHWP 258
gi 156362474 147 GYH-----VVEQKITSYSKNDKKMRILAKRLAENLDINFFDVKASSKEril---- 192
gi 821466435 165 GHK-----LEPLVLVKLSERYEQLEFLGRHIARKLNINYFDCIAVSYRHVVRHWP 214
gi 440904364 160 GHK-----LEPLVLVQLSERYEQMEYLGRYIARKLNINYFDCLATSYRHVVRHWP 209
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