Conserved Protein Domain Family
REC114-like

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pfam15165: REC114-like 
Meiotic recombination protein REC114-like
REC114-like members are necessary for meiotic DNA double-strand break formation. It functions in conjunction with Mei4. This family of proteins is found in eukaryotes. Proteins in this family are typically between 43 and 259 amino acids in length.
Statistics
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PSSM-Id: 317569
View PSSM: pfam15165
Aligned: 13 rows
Threshold Bit Score: 295.846
Threshold Setting Gi: 0
Created: 29-Jul-2016
Updated: 4-Aug-2016
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 190358937   21 WPLQRYARCIPSNTRDppgpclEAGTAPCPTWKVFD--SNEESGYLVLTIVISGHFFIFQGQTLLEGFSLIGSKDWLKIV 98
8_pfamImport    1 WPLQRYGRFMLSEARElsesgpKAGAVPSPTWKVFD--SSEESGYLVLTIVISGHFFISQGQTLLEGFSLIGSKNWLKIV 78
1_pfamImport    1 WPLRRYGRFMLLDNGEspgpssAAAAAPSPTWKVFE--SSEESGCLVLTIVVSGHFFISQGQTLLEGFSLIGSKNWLKIV 78
4_pfamImport    1 WSLKHYGRFLPNSTDRfgveaeAEAGSDSSSWKVFE--SNDKYGALVLTIVVSGHFFISQGQTLLEGFSLIDGKKWLKIV 78
5_pfamImport    1 WPLRRYGRFMPGGLGPasgsclSTGNHAFAGWKVLE--SNEESGFLVLTIVISGHFFISKGKDVLEGFSLIDASQWLKIV 78
12_pfamImport   1 WPLRRYSRFLPKATAG----------DSTSSWKVFN--SSESAGQLELTIVQSGHFLITQGHGLLEGFSLLNASNFLKVI 68
9_pfamImport    1 WKLKRYGRFIPDSDVK-----------GSTSWKVYE--KHEKKPELLITIVEAGYLLVLQGKECLDTIPLLCVADALKVH 67
10_pfamImport   1 WKLKRYGRFIPGSKET-----------GVKPWKVLE--TKDNKPEIVLTIVESGHLLVLQGQESLDTIPLLCGSDSIKVH 67
3_pfamImport    1 WKLRRYGRFLPSGKAK------PKTSGDNSAWKVFE--SSESAGQLELNILGSGHLLVSKGQELLEGFSLLNAQSFLKIQ 72
11_pfamImport   1 WGLKRYGRFLPQAKER----------GENSSWKVNNklNKTKKQHHMNKLGLQSKLLVNYCQLVTEGFSLSSAESFLKIH 70
2_pfamImport    1 WPLKRYGRFLSPTDSE-------DGERSGHSWKVFE--SNEESGHLILTIVVSGHFFISQGRTVLEGFSLIDSQKWLRIA 71
7_pfamImport    1 WPLQRYGRFVPTGDGEppapgqGARAASSHTWKVFD--SNEESGYLVLTIVISGHFFISQGQTLLEGFSLVGSRSWLKIV 78
6_pfamImport    1 WPLQRYGRFMPSGTGEpprpgqDAGAASSPTWKVFD--SNEESGNLVLTIVISGHFFISQGQTLLEGFSLIGSKNWLKIV 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 190358937   99 RRVDCLLFGTTIK--DKSRLFRVQFSGESKEQALEHCCSCVQKLAQYITVQV-PDGNIQelqLIPGP-PRATESQGKDSA 174
8_pfamImport   79 RRMDCLLFGATIKarSRSRMFRIQFGGESKEQALEHCCSCVQSLARYTTVEV-PDSITR---LSPGL-LWAGDHQGRDCA 153
1_pfamImport   79 RRMDCLLFGTTIK--DKSRMFRVQFSGESQEEALEHCCGCVQTLTQYVTVQE-PDRITQelqQSPGP-REAGESQGKD-- 152
4_pfamImport   79 RQVDSLLFGSILK--EKSRMFRVQFGGNSEEQALENCFACVQKLEQYITIYV-PDDLSQelqLGPSL-LIGPEGQGKDGA 154
5_pfamImport   79 RNADCMLFGSKAK--DKHRMFRVQFMGDSKSQAEGNCDDCVQKLADYVPVQV-IDSARQellQGHSL-LLDDQNHQKNAI 154
12_pfamImport  69 QKTDILLFRFKIK--SESRMFRVQFEGSSKEEALEQCQSAVIALQQYLFVEStPVQGNRfpmAVPSD------------- 133
9_pfamImport   68 QKLDNLMFRFTLK--GEGRMVRMQFDGRSRAEALVECSSAVEKLREYTTVS--QDDALQaanQSPAD-APAPATQQ---- 138
10_pfamImport  68 QKSDNLIIRFIVK--GESRMIRMQFDGCSMAEAINECSSAVEKLMEYIPVTT-QDYAPPqpnQPPAA-VPASAVQVAQMS 143
3_pfamImport   73 HKSDSLLFNIAMK--GESRLIRLQFDGSSREEAADFCSKAVRKLQDYVPVQ---KHLTTpapAAPSD-PAEPRTSAQQPP 146
11_pfamImport  71 QKSDSLLLHITMK--GESRMIRLQFEGSSRSEAVDFCSKAVERLQEYTPVp----------pAPPAAnHTTETQQQQQEG 138
2_pfamImport   72 RRADCLLLHAQSKq-NECRMFRVQFGGDSEEQTLEHCCSCVQKLAEYVPVHD-ADELSQnlcYSRSQ----VEDTEQNTS 145
7_pfamImport   79 RRVDCLLFGTT----SKSRMFRVQFAGESREQALGRCCSCAQSLAQYTAVE------------GPGPdLPAGDGLEEDGA 142
6_pfamImport   79 RRMDCLLFGTTIK--DKSRMFRVQFGGGSKEQALEHCGSCVQKLAQYVTVQV-PDGVSQelgLSPGP-LRAGESCAQH-- 152
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 190358937  175 KS-VPRQPGSHQHSEq----------QQVCVTAGTGAPDGRTSLTQLAQTLL--ASEELPHVYEQSAWGAEELGPFLRLC 241
8_pfamImport  154 KS-IPLQPGPCQDLE-----------RGKCVAAGVGAPEGRTSVAQLAQSIL--ASEELPLAYEQSAWSVEELGPFLRLC 219
1_pfamImport  153 ----PLQQGSSLILE-----------QHVCMAAGTGLLEERTSVTHLAQSIL--APEKLTLAYEGSSWGAEELGPFLRLC 215
4_pfamImport  155 ETgLRHQRGLHLN-------------VKQHHSSSYTFPDGRITMIQLAQSVL--TSAELPLAYEQAAWNAGELGPFLKLC 219
5_pfamImport  155 LR--KKQNKKHQHSAq----------QRAYVLSQIGKIKGRLSVAELAQYMMs-TNTKLPLAYQHSTWNAEDLNSFIRLC 221
12_pfamImport 134 -----------QAFMtfpfclsyyisEGEGSGATSEINQGSIPIRLLAQSFLgeSKLTLPLAYRHPTLPTEQLGPFLQLC 202
9_pfamImport  139 -TlCSNQSALIVFRKicvtgsrtktrQKQEVRADPQAVQGKITMEQLTQHFLgeTVVRLPEVYRHSYFTQGDLELILRIC 217
10_pfamImport 144 TTrCPQH---IMCQQt---------cQEKAVGVKPEVVQGTVSIKRLTQVLI--VTVTLPRVYQHSSFGQGDLEHFLRVC 209
3_pfamImport  147 KNiLEQEYSLLQAPE-------------DAPRAAPAVAEGPLSIKHLSQLFLgeGELCLPMAYHQSSLPSGDLEALLRLC 213
11_pfamImport 139 RSmQVLPFCPHVQRKt----------PAEKLQAVPDVSQESLSIKHLAQYFMgeRGLSLPLAYHQFTLPPGDVEDLLRLC 208
2_pfamImport  146 VLrVPEEPLP-----------------DSCINFG-----ERRSTMQLAQSVLn-QKFELPLAYRHSAWSAQELGPFIRLC 202
7_pfamImport  143 GH-VPPQHAA-QDPE-----------QQACRAAGRAGPGPRTSVTELAQAIL--ATEELPPAYRQCPRGAGELGPFLRLC 207
6_pfamImport  153 ---VPPQQGEHYIEEp----------YKTNRTLIFGVCFLNISLKKSPQSLL--VSEARPPICEQPAWDAEELGPFLRLC 217
                         250       260
                  ....*....|....*....|
gi 190358937  242 LMDQNFPAFVEEVEKELKKL 261
8_pfamImport  220 LMDQNFPAFVEKVENELKKL 239
1_pfamImport  216 LMDQNFPAFVEEVEKELKKI 235
4_pfamImport  220 LMDQNFPAFVEDVEKELKKL 239
5_pfamImport  222 LLDQSFPAFVEEVEKQLKKI 241
12_pfamImport 203 LLDQNFPAFVEQVERELKKL 222
9_pfamImport  218 LLDPSFPAFVEKVETELRKL 237
10_pfamImport 210 LLDPTFYGFVEKVEGELRKL 229
3_pfamImport  214 LLDSAFPAFVEEVEKKLKEI 233
11_pfamImport 209 FLDSGFPAFVEEVENKLKAL 228
2_pfamImport  203 LMDQHFPAFVEDVEKELKKL 222
7_pfamImport  208 LLDQHFPAFVEEVEKELEKL 227
6_pfamImport  218 LMDQNFPAFVEDVEKELKKL 237
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