Conserved Protein Domain Family
CAP-ZIP_m

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pfam15255: CAP-ZIP_m 
WASH complex subunit CAP-Z interacting, central region
This domain is found on WASH complex subunits FAM21 and CAP-ZIP proteins, as well as on VPEF (vaccinia virus penetration factor). This family of proteins is found in eukaryotes. Proteins in this family are typically between 305 and 1321 amino acids in length. The exact function of this region is not known.
Statistics
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PSSM-Id: 317637
View PSSM: pfam15255
Aligned: 13 rows
Threshold Bit Score: 180.72
Threshold Setting Gi: 768916386
Created: 29-Jul-2016
Updated: 4-Aug-2016
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166971555   944 PFKTKEPStRIGKI-QANLAINPAALLPTAASQISEVKPVLPELAFPSSEHRRSHGLESV--PV-LPGSGEAGVSFDLPA 1019
gi 81865867    932 PFKSREPSsRIGKI-QANLAINPATLLPSVAPQIPGAKPASCELAFPSSEPARSHIREAV--PT-LPGSEEAGVSFDLPA 1007
gi 821450883   861 PCKTKEPSsRIGKL-QADLAINPAALLPGAAPKISGVKAAVPGFAFTASEPDGVKGMESA-------SAGETGVSFEDPA 932
gi 637338065   828 lFNSSEA-----KP-LANLDINPTVFLPSGT---SGMKRFASYPKTPCYEPHSIQHAKIA--SV-VKGNNETGVSFDSPM 895
gi 597757218  1015 PVKSKETS-RIGKL-QANLAINPASLLPGAAPRVPGGVSVIPGLAPSHSARASGPLPGFAgpPE-PQARSEGAVSFDTPA 1091
gi 1040662009  979 PLKSKKTS-RIGEL-QAVLALNPAGLLPGAVPRAPGAVSVIPGLAHTGLPAAARTMPD-------HQGSSEGGVSFDSPA 1049
gi 768916386  1005 PVKAKESStRIGKL-QASLTINPAALLPGAAPGRPGAVGLLPGTASKSSSGVLSSV--FP--PVgAQTGSEQGVSFDAPV 1079
gi 47223319    751 PRKPDNSGsKVDSLsQASLLINPAALLPGVTPSLPGAVSVLPGAAPKSSAGVLSSSPDLT--PMgTQVASEQGVSFDAPV 828
gi 655865794   917 PFKPKEPStRIGKL-QAHLAVNPAALLPAAAPQPPAGKSISPELAFPSPEAGRSRALGSA--SP-LAGSGEAGVSFDFPA 992
gi 942096983   392 PLKTKEPSpRIWKI-QANLAINPAALLPPAAPQISGMKSVLPESGAPSSEPGRMQSLDRV--PT-PPGSGEAGVSFDLPA 467
gi 928175003   944 PFKTKEPSpRIWKI-QANLAINPAALLPAVAPQISGIKPVLPELAFPSSEPERIHSLESM--PT-LPSSGEAGVSFDLPA 1019
gi 60099223    488 PIKTKEPSsRIGKL-QANLAINPAALLPGAVPKISSVKSPFPILNTPLHEPNDVQSSEAF--PA-AGNNEELGVSFDQPM 563
gi 823462880  1025 piktkepssriGKL-QANLAINPSALLPGAMPKVSNVKSPLPVLDTPLHEPKEAQNSEAF--SA-AGSNEELGVSFDQPI 1100
                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 166971555  1020 QADTLHSANKSRVKMRGKRRPQTRAARRLAAQESSET----E--D--MSVPRGPiaqwADG--AISPNGHR 1080
gi 81865867   1008 QADTLHSANKGRVKVRGKRRPQTRAARRLAAQESSEA----E--D--VTIDRGPvtqlSSS--PVLPNGHQ 1068
gi 821450883   933 QADTLYSVNKSRITMKGKRRPQTRAARRLAAQESSEA----E--D--RSDAEGSq--lGREhvISPPIQEQ 993
gi 637338065   896 QADTLQNTNKGRVKMSGKRRPPSRMARRIAAQESIDN----E--T--TGAEYPSppllKENsvPSALKYPS 958
gi 597757218  1092 QVTTLQSANKDRAKVATKRRPQTRAARQIAAQRSVEArrdmE--E--VDSQGGT----ASStpPFNPISAR 1154
gi 1040662009 1050 LISTLLNANKGRAKGAGKRRPQTRAARHLAAQQSDEAs--gE--N--VSVQKNEpa-mAASlpPFNPVSVR 1113
gi 768916386  1080 QVSTLPSAHKTRAKISAQRRPQSRAARQQAAKISAAK----EnaV--LPISQPSgfvlSSEdkSSRAVStd 1144
gi 47223319    829 QVTTLQSAHKSRAKITAQRRPQSRAARQQAAQTPAAD----E--DavLSHTGPAglvlPSAdkssraastg 893
gi 655865794   993 QADTLHSANKGRVKVRGKRRPQTRAARRLAAQESSET----E--V--TSGPRGPaahlADG--AVSPSSWQ 1053
gi 942096983   468 QADTLHCANKTRVKVRGKRRPQTRAARHLAAQESTEA----E--D--VGSPRGFvaqlTDG--ATSPDGRQ 528
gi 928175003  1020 QADTLHSANKSRVKVRGKRRPQTRAARRLAAQESSEA----E--D--VSVSRRSiaylADG--DVSPGDLQ 1080
gi 60099223    564 QADTLHSANKTRIKVTGKRRPPSRMARRLAAQESGES----E--E--VDSAKEPqfsvLKQksVVENVKEL 626
gi 823462880  1101 QADTLHNANKTRIRVPGKRRPPSRMARRLAAQEAEAS----E--E--MDATKESqfslPKQtsAVVNIKEP 1163
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