Conserved Protein Domain Family
DUF4591

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pfam15261: DUF4591 
Domain of unknown function (DUF4591)
This protein family is a domain of unknown function. It is found in eukaryotes, and is approximately 120 amino acids in length. In humans, the gene encoding this protein lies in the position chromosome 11 open reading frame 63.
Statistics
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PSSM-Id: 317643
View PSSM: pfam15261
Aligned: 14 rows
Threshold Bit Score: 84.3885
Threshold Setting Gi: 313224344
Created: 29-Jul-2016
Updated: 4-Aug-2016
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 762152705 1439 LGPDL--DneTYKEKLEKRHKQFEYARMVMEKNRHE--L------DVKk--PPSNAKKDEEKp-nK--RKT-A-IEYSKN 1501
gi 973212983  761 LGPSN--L--VSEETAGKMKRQRQYSDLVREQNKKMsqN------PPF---PTHNAVASGKTdvaP--RRK-A-LEYAKN 823
gi 156376537  458 LGPDT--DseEYKQKLYKLNKQKEYAEMLRSQHAALkpHw-----EKKa--PPLNPTPARLKqaeA--KRK-AaMNYAKT 525
gi 390338725 1394 LGPDK--E--TMGFRSEKVARQRDYARQVMEQNKKIirT------NPNa--SNTPGKDSPQTeasK--REL-A-LEYAKQ 1457
gi 260836777 1158 LGPDL--D--RVQDKVDKKRRQKEYADSLRQQHAKQkaD------WQKkrdEQPYYQQEEEDdlyS--KRE----VYAKS 1221
gi 195995571  236 LGPDKlnN--EYQEKQERAFKQQEYAKLIRQQHLKEkkR------WI----SRNANKEANNQnqlS--RAKlA-AEYAKN 300
gi 313224344  409 LGPEK-----APTQDSLRYERRKNFAEAVRYMNKGKikPqveekvDIKk--LELERKREI--------RKK-Q-LEYAKS 471
gi 958705954  661 LGPDL--E--SIRDKMQKLKQQKEYAKQVKEYNMKt--L------SILs---KPQTAKTETKp--AvpRQK-A-LEYAKT 721
gi 149041395  364 LGPDF--A--SIRDKMQTLLQQKEYAKQVKEYNMKt--L------SVLs---KPQTSKTDSKs--TisRKK-A-LDYAKT 424
gi 395520098  660 LGPDF--E--SIKDKITKLKQQKEYAKQVKEYNMKa--L------SSGs---KPQTAKPESKp--SisRQK-A-LEYARK 720
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 762152705 1502 IPKp-----------------nVKARPNQ------Yn------------SYEVAAQLSPAAKKSGPPsPTQTVD------ 1540
gi 973212983  824 IPK-------------------PKPPLQP------K-------------TNQKVAKEGYGEHALYLE-DVDLSQ------ 858
gi 156376537  526 VPKp-----------------kTMTPRQP------Y------------------------IRTEQPQsLAETGD------ 552
gi 390338725 1458 IPRp-----------------rIPTPPEV------LhdrlygsgansrsSGAGSRSSSVREETAGTRdENTALE------ 1508
gi 260836777 1222 VPKpkpapppkavtvletqhtdTVPYHHP------P-------------PMENHTPNIMRIEREDPAqPVPSPV------ 1276
gi 195995571  301 IPRp-----------------kPAAKPKE------T-------------TN---NKASLTTKKGNPQtQKKSTEfsnrkv 341
gi 313224344  472 IPPp-----------------pKPPNNRRlktdhtL-------------SNSKSGRSAPPTSTTNLHgPSPTDN------ 515
gi 958705954  722 IPKp-----------------kPSNLT--------------------------DQASKEKKNPTHAGkEDTLPEi----- 753
gi 149041395  425 IPKp-----------------kPPNLPYQ------T--------------------MKKTNNSKHSEkEGSLPEi----- 456
gi 395520098  721 IPKp-----------------kPVLPSNQ------N-----------------DQELKQTSNPSVSGkERNLPEi----- 755
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 762152705 1541 --------------------------------------VIDLQKLKQRHDQEKQNVASI 1561
gi 973212983  859 --------------------------------------LARLEMLQKRHEEEKQVVANF 879
gi 156376537  553 --------------------------------------LTLVEILRLRHEKEKHEVDVI 573
gi 390338725 1509 --------------------------------------MARLQELTQRHNQEKDALDRL 1529
gi 260836777 1277 --------------------------------------LSEIQKMRMRHEKDRANAEAI 1297
gi 195995571  342 avnsaarsftskhsmtissdnlanfvqntenadaddtkLSVIEMLKQRHERDKLAAAKI 400
gi 313224344  516 ---------------------------------------ANLDALLSRHKTEQARVTRL 535
gi 958705954  754 ---------------------------------------SLLEILQSRHEREKQAVAAF 773
gi 149041395  457 ---------------------------------------SLLEILQSRHEREKQAVAAF 476
gi 395520098  756 ---------------------------------------SLLEVLQSRHEREKQAVAAF 775
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