Conserved Protein Domain Family
BMP2K_C

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pfam15282: BMP2K_C 
BMP-2-inducible protein kinase C-terminus
This family represents the C-terminus of BMP2K and related proteins.
Statistics
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PSSM-Id: 317657
View PSSM: pfam15282
Aligned: 16 rows
Threshold Bit Score: 157.338
Threshold Setting Gi: 688575502
Created: 28-Jul-2016
Updated: 4-Aug-2016
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 637308402   798 DEFDVFTKAPFGRKmsqqddl-isgcenqPIPISPMSpVDVFGCIPFHPss-vSKSDESKEDLFGLIPFEEiagseqqqq 875
gi 512815037   857 EEFDVFSKAPFSKKveql-------dcqvTPSISPTS-VDIFGCSPFEPapseGEKSCSREDIFGLVPFEEitgnq--tq 926
gi 351708085    85 DDMDIFSKAPFVSKg-------------nVAPSQPEE-VDVFLRAPF--------------------------------- 117
gi 731493120   920 DDVDIFSKAPFISKs-------------sVASSQPEE-ADVFLRAPF--------------------------------- 952
gi 821460346   842 DGMDIFTKAPFVTKg-------------hMAPQVPED-ADVFLRAPF--------------------------------- 874
gi 971429873   852 DEADVFTKAPFISKg-------------sAALRHPEE-ADVFLRAPF--------------------------------- 884
gi 565312253   663 DDFDVFTKAPFSRRisqqdds-itgleplTSPVSPKS-VDVFGCIPFQPvs-iQRHGEAREDLFGLVPFEEitgsq--qq 737
gi 823459319   914 DDFDVFIKAPFSKKvpqrdgq-gsgleplLSPTSPRS-VDIFGCTPFQPsl-vAKSAGSRQDLFGLVPFEEitgsqqqqq 990
gi 344284855   871 EEFDVFTKAPFSKKvnvqdsh-vvgseahTRPGCPKS-VDIFGSTPFQPfptpVSKSESNEDIFGLVPFEEitgs---qq 945
gi 1032912980  793 EDFDVFTRAPFNKKvnnvqdwptagpdtrPLPARPRS-VDMFGSTPFQPfstsASRSESREDVFGLVPFEEitgs---qq 868
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 637308402   876 qkAKqqQRNLQKLSSRQRRMKQEGSK------TngkRHHGTPTSTKKTLKPNYRTPERVRRHKKAGRRDSQSSNEFLTIS 949
gi 512815037   927 hkVKh-QRNLQKLSSRQRRTKPETAS------SngkRHHGTPSSTKKAPKPSYRTPEKVRRHKKGGRRDSQSSNEFFIMS 999
gi 351708085   118 --TK--KKSMEELTVIQSSSQELPAQ------A---SLLSQAVDV-----PLFSGHERAGYTSV---QAQYSMAGFVQQS 176
gi 731493120   953 --TK--KKSMEELTVAQTTSQDLPTQaslliqT---------GDVPTGASPLLSSLDRAVFTSV---RSQYSMAGFVQQP 1016
gi 821460346   875 --TK--KKSTEELMAAQGATMDLPTQ------S---TLHSQMGDGVPVINPLLSHLDRGIHPTALSPLAQYPMVGFLHQS 941
gi 971429873   885 --TK--KKSMEELLSHSVPKEPLVFL------S-------PAADIQHRTTPAFQSLDAVVSGPSA--RPQYPSAGFALLT 945
gi 565312253   738 hkAKqqQRNLQKLSSRQRRMKQEGSK------SngkRHHGTPTSTKKTLKPSYRTPERARRHKKAGRRDSQSSNEFLTIS 811
gi 823459319   991 qkVKq-QRNLQKLSSRQRRMKQEVSK------SngkRHHGTPTGTKKGLKPSYRTPERARRHRKAGRRDSQSSNEFLTIS 1063
gi 344284855   946 qkVK--QRSLQKLSSRQRRTKQDMSK------SngkRHHGTPTSTKKTLKPTFRTPERARRHKKVGRRDSQSSNEFLTIS 1017
gi 1032912980  869 qkVK--QRSLQKLTSRQRRTKQDVSK------SngkRHHGTPTSSKKPLKPPYRTPERARRHKKVGRRDSQSSSEFLTIS 940
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 637308402   950 DSKENiSIAMPDNKDRVSSLQT------------------EDALLDPFG-AKPFHPTELvRHPQHQGLGDNR-GDHNT-V 1008
gi 512815037  1000 DSKENiSISLSDGKDCGHLLQT------------------DESLIDPFG-AKPFHPQDL-RLPQHQGLTDNH-GDHQT-A 1057
gi 351708085   177 NLPSH-SLQAADHLDSISPMGPsmepgshsndrnkgpqpqKEAVSGPVA-GKPFRPQSLaKYSRHYSPEDEPsPEVHPiA 254
gi 731493120  1017 NLPSH-SVQAADHLESFSPRGSslepgghpndrnkgpqpqKEAVLGPVA-GKPFLPPSLsKYSRHYSPEDEPnPEAQPiA 1094
gi 821460346   942 NLPSN-SIQSAESLDNLTSKGTldsgghpid-rnkghpsqKEAVSSSGA-SKSFRPQSLsKYSRHYSPENEPtLEAQPiA 1018
gi 971429873   946 NLPPS--VRAAEEHSPPAGVQPepgers------paqagpQECTLGPVTnSRPFRPQALsKYSRHYSPEDGPgLDVQPiA 1017
gi 565312253   812 DSKENiSISLSDSKDRVNPLQG------------------DDNLLDPFG-AKPFHPAEGlRLPQHQGLGDNR-GDHNT-V 870
gi 823459319  1064 DSKENiSVALTDSKDRANPLQT------------------DEALLDPFG-AKPFHPPELmRHAQHQGFGDSC-GDHGTvV 1123
gi 344284855  1018 DSKENiSVALTDGKDRGTILQP------------------EESLLDPFG-AKPFHPPDLtRHPSHTGLSDIR-ADHNT-V 1076
gi 1032912980  941 DSKENiSVALTDGRDRGSGLQP------------------EESLLDPFG-AKPFHPPDLsWHQSHQGLSDIC-VDHNT-I 999
                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 637308402  1009 VPGRPRQGSLLGSIqsgdglkltddfGAVPFTELVPSMA-----SQQSQqqa--geLDPFGAAPFPSKQ 1070
gi 512815037  1058 MSGRPRQSSLHGGYhsndnl-nmddfGAVPFTELVLQSVtqqnsQQTQQpl----eFDPFGAAPFPSKQ 1121
gi 351708085   255 AYKIVSQTNKQSIA------------GSVSITSLSSRTT-----ELPA--------TDPFALAPFPSKA 298
gi 731493120  1095 AYKIVSQTNKQSIA------------GSVSITSFPSRTT-----ELPA--------ADPFALAPFPSKS 1138
gi 821460346  1019 AYKVVSQSNKQSIS------------GSVSITSFSSRTT-----ELPS--------VDPFALAPFPSKS 1062
gi 971429873  1018 AYKVVSQTNRQAIA------------GSVSVAPLAARTT-----ELPA--------ADPFASAPFPSKA 1061
gi 565312253   871 VPGRPRQSSLLGSIhssdsvkltddfGAVPFTELVPSVK-----SQQSQqqq-aveLDPFGAAPFPSKp 933
gi 823459319  1124 VAGRPRQSSLHGAIhggdgl-ktddfGAVPFTELVVQST-----QSQPQqa---leLDPFGAAPFPSKQ 1183
gi 344284855  1077 LPGRPRQNSLHGSFhsaeal-kiddfGAVPFTELVVQSI-----TSHQSqqsqsveLDPFGAAPFPSKQ 1139
gi 1032912980 1000 LPGRPRQNSVHGSFhsadal-rmddfGAVPFTELV---------TPRESqqsqpveLDPFGAAPFPSKQ 1058
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