Conserved Protein Domain Family
PAGK

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pfam15284: PAGK 
Phage-encoded virulence factor
PAGK represents a new of virulence factors that is translocated into the host cytoplasm via bacterial outer membrane vesicles (OMV). Members are small proteins composed of ##70 amino acids. In Salmonella they are secreted independently of the SPI-2 type-III secretion system, T3SS. The OMV functions as a vehicle for transferring virulence determinants to the cytoplasm of the infected host cell. OMVs are released from the cell envelopes of Gram-negative bacteria and comprise a variety of outer membrane and periplasmic constituents, including proteins, phospholipids, lipopolysaccharides, and DNA.
Statistics
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PSSM-Id: 317659
View PSSM: pfam15284
Aligned: 2 rows
Threshold Bit Score: 63.0019
Threshold Setting Gi: 1173488815
Created: 29-Jul-2016
Updated: 4-Aug-2016
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 499298075  1 MKhvKSVFLAMVLILPSSLYPALTIAADSQDHKKEETIKPMpqkwcnlwpAGipfpedwfKMCR 64
gi 321222709  1 MK--NSIFLPLLLVLSATTFSALVMAASHSPHQIIQNIFPV---------AG--------RQIS 45
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