Conserved Protein Domain Family
MRI

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pfam15325: MRI 
Modulator of retrovirus infection
MRI, or modulator of retrovirus infection, is a family of eukaryotic proteins that regulate the activity of the proteasome in the uncoating of retroviruses.
Statistics
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PSSM-Id: 317698
View PSSM: pfam15325
Aligned: 15 rows
Threshold Bit Score: 57.4965
Threshold Setting Gi: 664758036
Created: 29-Jul-2016
Updated: 4-Aug-2016
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81891356   53 TVYCMNEAEMVDVALGILIE-GRKQEKPWEQPSLVAPDKLQLSPPCSes-phTSSPGSSSEE---EDSRTD--SPALGLS 125
gi 664758036  53 TVYCMNEAEMVDVALGILIEtsgarppdgglkvqtgaesgmsaampgvmtilpssllerprpmkcslhltvkrkveeevn 132
gi 558123126 113 TVYCMSEAELVDVALGVLIE-NRQQEKALEQRPLAGTAEPELSPTCSe---gPASP-ETSEG---EDSGEA--ALPPGLG 182
gi 410952929  53 TVYCMSEAEMVDVALGILIE-ARKQEQPLEPLTPAGADKPELSRAHSalspsPSSPGRRSED---EDNEKD--ALPPGHS 126
gi 119891359  51 TVYCMNEAEVVDVALGILIEeDRKQEKPLEPPPLAGADKPERSPASPap-psPSPRWSRSEDseeEDRGAD--------G 121
gi 545882416  47 TVYCMNEAEMVDVALGILIEqGRKQEEPWEQPPLAGADKPARSPASSap-paPRPPGTRSED---EED-----TPAPGPR 117
gi 512978483  51 TVYCMNEAELVDVALGILIE-GRTQEKPWEELAVAGAEKTELCPTGSrs-phTSS-GGNSDE---EDSGNHglRPEAGPS 124
gi 884931534  51 TVYCMNEAEMVDVALGILLE-GHAWEKPQEELAVGGTEKAELCPAGPws-phTSS-GGNSEE---EDSEND--RPTLGLS 122
gi 655816625  49 TVYCMNETELVDVALGILIE-DGKQEKAGELPSLLGADKPEGSPSPSp---hTSS-GSSSDE---EEGEDD--APVPGLS 118
gi 397484679  52 TVYCMNEAEIVDVALGILIE-SRKQEKACEQPALAGADNPEHSPPCSms-phTSS-GSSSEE---EDSGKQ--ALAPGLS 123
                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*....
gi 81891356  126 PARGPEASNSPCSRSPEegkEE--------------EDELKYVREIFFS 160
gi 664758036 133 nkgqsrdldlnfckrclrvgwkrg------------------------- 156
gi 558123126 183 RPQGPAGLEPACSSSPE---ED--------------EDAFKYVREIFFS 214
gi 410952929 127 P-QGPAGSDSARSRSPE---ED--------------EDMLKYVREIFFS 157
gi 119891359 122 PAPGPAGSDTACSRSLE---ED--------------QDELKYVREIFFS 153
gi 545882416 118 PPPGPAGSDPARSPSPE---QD--------------HDALKYVREIFFS 149
gi 512978483 125 PSQRPETFTSACSRSPEq--QE--------------EDVFKYVREIFFS 157
gi 884931534 123 SSQRPGMPTSACNRDPKq-eEEeevkeekveeeeeaEDVFKYVREIFFS 170
gi 655816625 119 PPNTAGGRRP----EEEekeEE--------------EDVLKYVREIFFS 149
gi 397484679 124 PSQRPGGSSSACSRSPEe-eEE--------------EDVLKYVREIFFS 157
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