Conserved Protein Domain Family
DUF4614

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pfam15391: DUF4614 
Domain of unknown function (DUF4614)
This domain family is found in eukaryotes, and is approximately 180 amino acids in length. There is a conserved EALT sequence motif.
Statistics
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PSSM-Id: 317757
View PSSM: pfam15391
Aligned: 28 rows
Threshold Bit Score: 135.195
Threshold Setting Gi: 780065842
Created: 29-Jul-2016
Updated: 4-Aug-2016
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74718575  474 NSPSLTASEPTAH-SkESLDRTLdalsESS----SSVKTDL---PQTAESRKKSGRH---VTRVLVKDTAVQTP---DPA 539
gi 908531212 414 ySRAFSEASHSSTsRtSDRSHTSksnsQGR----SEDSRSSllhEGQASYQQSRRHT---SARKVLKETAVQTH---SGR 483
gi 548349959 543 ySRAFSEASHSSTsRtSDRSHTSksnsQGR----SEDSRPSllhEGQASYQQSRRRT---SARKVLKETAVQTH---SGP 612
gi 699244822 394 lKDTESITHDVSSiKeSSQSVAStissESEtqskQTTNTPSyteTFESDTSATESDStvlKPATVKTETAVQTE-----P 468
gi 260823806 567 dvsrsdrsrrskgsrkTDSEDSYsettRSRtltdSTVSDSRtsrTRSRTPPRKAVKA---------SDVGVQTSvedQLG 637
gi 556957937 619 lSERFEENKRKYSqSfSSHTSSFssssSSSlqtsQSTGNQRnrrKSSAQG----------------KEAAVQTE---HAA 679
gi 301626134 467 ESMHTETSK-----SiHSESDSSasltSSSrrggSSPHGSYtnrSKHHQTKRRADK----VQKITIKETWVQTS---EPE 534
gi 156396648 288 SSRSPHSSRSSHSsRsSHSSRSShssrSSHhrsnKSNDSNSrsyNRKNESNKHNRNTceiATQTVPEISSMQST------ 361
gi 973201952 512 SSFSSPAPQSEVDrKkADLSCRQgvysRSSasspSASGSGTltpPHETQSP---------HQRKAVKDTAVQTQ---FDG 579
gi 597764682 452 QSHSYSVDDHTLSeEsPKSTGVQysksESSlshsRSSPSDSyssDDTITPSKPQSQS---VRRRPVKDATVQTQ---RDA 525
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74718575  540 FTYEWTKVa--SMAAMG---PALGGAYVDPTPIANHVISADAIEALTAYSPAVLALHDVLKQQLSLTQQFIQASRHLHAS 614
gi 908531212 484 LASTWPT----DIPAVD---PMVSMTYINPSPVVTHTLNAEMVEAISTFNPAVFALNELLKQQLAMTRRFIESSRHLHSS 556
gi 548349959 613 LASTWPT----DIPAVD---PMMSMTYINPSPVVTHTLNAEMVEAISTFNPAVFVLNELLKQQLAMTRRFIESNRHLHSS 685
gi 699244822 469 VDIHAKDDpfkGIAFSPvfpPTL-------------VVSNEALAALTSYSPATLALQDMMKRQLALTKDFIERSERLHQS 535
gi 260823806 638 LVHQWTAEs--GYAALG---PQYGAGYTDPTPVATHVVNPDALEAMTSYSPSVLGLNDLLRQQLQLTQQFVTNTRRLHQF 712
gi 556957937 680 FTYSWANd--gGTAVLG---PSHGMMYVDPTPIASHIVSPDAVEALTAYSPAIFALNDMLRNQLLLTKEFVKISSHLHAS 754
gi 301626134 535 LGYYWPL----GTSDLR---LSSAPVFLEPASIARHAVSPEVIESLTTYSPMALALNDMLKQQLLLTQTFVDMARQLHLS 607
gi 156396648 362 ----LPQglgvGMAAVG---PQLGMQYVDPSPIATHVVSPEAMEAITAYNPAVVALTDMLRQQIRLVEQFVDANNRMYQA 434
gi 973201952 580 LSYSWSN----GMAVLG---PSIGTSHLDPTPVASHVVSADAIEALTAYSPAVFALNDMLKQQLALTRQFIDNTRHLHTS 652
gi 597764682 526 LTYSWST----GPAVLG---PSIGMSYVDPTPIASHTVSAEAVEALSAYSPAVFALNDMLKQQLALTRSFIESSRYLHHT 598
                        170       180
                 ....*....|....*....|....*..
gi 74718575  615 LLRSLDADSFHYHTLEEAKEYIRCHRP 641
gi 908531212 557 LVQSLEPPNYKYTTLEDTKKLIPMHKS 583
gi 548349959 686 LVQSLEPPNYRYTTLEDTKKLIHMHRS 712
gi 699244822 536 TMSSLTP-NYHYTTLEETKQIINAHRK 561
gi 260823806 713 YVNSLQAD-HSYTTLQDTLQFIQEHRR 738
gi 556957937 755 VVNSLERDPYHYTTLAEVKQFIRENKA 781
gi 301626134 608 TVRSLEAEVYHYTTLEDTKKYIRHQKS 634
gi 156396648 435 YTSNMNNN-YKYTTLEDTMEFIRRNRP 460
gi 973201952 653 LLQSLGPARYRYTTLEDTKEFIQSHKS 679
gi 597764682 599 MVESLGPADYRYTTLEDTKGFIRCHRA 625
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