Conserved Protein Domain Family
PH_4

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pfam15404: PH_4 
Pleckstrin homology domain
This Pleckstrin homology domain is found in some fungal species.
Statistics
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PSSM-Id: 317769
View PSSM: pfam15404
Aligned: 36 rows
Threshold Bit Score: 188.209
Threshold Setting Gi: 353239077
Created: 29-Jul-2016
Updated: 4-Aug-2016
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74691837   998 HQGILYQKPRKHSVFKKCFLTLVPGFIILYECFK--RSM-MGYSYKTVAYHHYMTVPLEECYIYSGNITSqDLLrREREF 1074
gi 684175451  881 MSGSLYLKPHRRAAFHRSQVILCGGKLLIYQATV--RKS-TGAQVRHIHQEKQQVVDLKDCYVYSGLIVEdDLLyQNTTF 957
gi 398391408  682 MSGALFRKPRKHTTFTRCHVILSHGHLLIFQDTL--RKR-TGKKLVHIHHERIASMSLQGCYLYSGLLTEnDLLyQNQTF 758
gi 396487453  941 MSGMLYRKPRIHAPFTRCSVILTAGTLIMFRDVL--RSR-VGKQLAHIHHERIANLDLKDCYIYSGLLTEsDLLyQNQTF 1017
gi 667829444  928 MSGILYRKPRRHSTFTRCSVILSSGRLLIFQDSL--RTA-TGKEILHIHHERIASLDLTDCYLYSGLLTEnDLLyQNRTF 1004
gi 407920881  553 iSGVLFRKPRRHATFTRCSVILSAGTLLIFQDSL--RKT-TGKQLEHIHHEHISTLDLRDCYLYSGLLTEnDLLyQNRTF 629
gi 734682645  994 MSGNLYCKIRRRSAFRDCSVILTEGQILTFQSHL--RKL-SGQEIPHTHQERQWALDLRDCYIYSGLITSsDLLyQNHTI 1070
gi 240275108  774 MSGLLYCKPRRRSAFTACNVILTEGQILCFQSLI--RKL-SGEETPHTHHEREWVLDLDDCYIYSGLITNsDLLyQNHTI 850
gi 388856304 1877 RSGRLFHKKSSYSAFKARDYVLIAGRLLCFKLVRsvRTSrARQNNGIFHRRQETVIHLRDAYVYSGKLSE-DML-KNGRS 1954
gi 343425843 1863 RSGKLFHKKSSYSAFKARDYVLIAGRLLCFKLVKsvRTTrARQNNGIFHRRQDTVIHLRDAYVYSGKLSE-DML-KNGRS 1940
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74691837  1075 NSGNP------------GNRSLPRVY-QDGWKSLEDEPYRCFTLWFG-NRAISDYNVAGKHSDSDEVqdeipesgt---- 1136
gi 684175451  958 DANHP------------GMASLPRVYlDDGWTSADVDVMTCFVVWMNrKKGWFRTAAAVAEEQTQPQsqpqsdgpvdvtt 1025
gi 398391408  759 DSNAP------------GHHSLPRIYlEDNWTSTDEDAMTTFVIWHPkSTSWFKSSHTVDDVKAQQQesss--------- 817
gi 396487453 1018 DANKP------------GHHALPRIYlEDGWTSTDEDVMTTFVIWHGkAKSWFRAEEGAGGgeq---------------- 1069
gi 667829444 1005 DSNKP------------GHTALPRIYlEDGWTSTDEDVMTCFVVWHGrRRSLFRRGDASGSGseg--------------- 1057
gi 407920881  630 DNNKP------------GHTALPRIYlEDGWTSSDEDYMTCFAIWHGrKKSLFRRGSNDSREKevr-------------- 683
gi 734682645 1071 DTNLP------------GQRASPRLYiTDGWTSSDEDIATCFVVWYNaRKTVFRSQEwqh-------------------- 1118
gi 240275108  851 DTNLP------------SQHASPRVYtTDGWTSSDEDIATCFVLWQNsRKSVFRSQEkq--------------------- 897
gi 388856304 1955 EPAQAvsglfgggsnsgKRHRVPRVY-ADGLFSVDDDEDCTFVIRYRpERVNTPADPSVGSLTTKKGkaaaqr------- 2026
gi 343425843 1941 DPAQAvsgiggggsnsgKRHRVPRVY-ADGLFSVDDDEDCTFVIRYRpERVNTPANPSVTSLHGKDAka----------- 2008
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 74691837  1137 ---htqpltasgNFENQs-----------DQKTGKRF-RVSGKSMVFMARSRQDRDVWIYKIHCEL 1187
gi 684175451 1026 esntknsaggsrGNTRA------------KLRRVGQL-GVPGRGMVFKCRSRAERDHWVLSVASEI 1078
gi 398391408  818 --------ksegGAVKT------------KLTRVSQL-GATGRSVVFKARSRAERDHWVLAIQVEI 862
gi 396487453 1070 ---------srkEGKRT------------KMKRVAKL-GSKGRSMVFRARSRAERDHWVLAIQNEI 1113
gi 667829444 1058 ---------vegEGRRS------------GFRFVSSL-GVPGRSIVFKARSRAERDHWVLAIRTEI 1101
gi 407920881  684 ---------ekeGGRRS------------RFKLVSQL-GVPGNTMVFKARSRAERDHWVLAIQTEc 727
gi 734682645 1119 ---------kgnALART------------KWKRVSAL-GVPGRSIVFKARSRAERDMWVLAIETEI 1162
gi 240275108  898 ----------geTGERTk-----------KWKKVSTL-GVPGRSIVFNTRSRAERDMWVLMIETEI 941
gi 388856304 2027 ------sssaagRTETAgs-----------saSVPALeDKRHKYIAMRARCKTERDLWVRCITYEI 2075
gi 343425843 2009 ----------kaRGKAAgtsakdkkeaqqAAGSVPRLdDKTHKYIAMRARSKVERDLWVRCITFEI 2064
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