Conserved Protein Domain Family
PPP1R35_C

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pfam15503: PPP1R35_C 
Protein phosphatase 1 regulatory subunit 35 C-terminus
This is the C-terminus of protein phosphatase 1 regulatory subunit 35. This protein interacts with and inhibits the serine/threonine-protein phosphatase PPP1CA.
Statistics
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PSSM-Id: 317853
View PSSM: pfam15503
Aligned: 17 rows
Threshold Bit Score: 96.6635
Threshold Setting Gi: 674574286
Created: 29-Jul-2016
Updated: 4-Aug-2016
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350646355  185 PVFNTTKALEQ-EIKSLSR-KvnnaskehytdeiRLEAERVVNEACNTLPA-GDNSINPlilNPRITVNVPENVSTYENL 261
gi 260790797  180 PEFNTTLALGK-ELQKLKF-G-------------EFDAKAAALEKLKTSEQ-VQEKVSE---KSAEGVNIAPAEQKYRDL 240
gi 1043402188  22 PRMHSTAALKE-QAELEAG-Q-------------EFHADRAVQRELERSYR-VRRSIES---EAARALNVARAHSLYQGL 82
gi 198417578  276 sKYHSSLVAGQ-ELQKLQE-E-------------EFDAVTAVKKKLEDDKN-LRAHIST---QAATGTNIDPDEVLYNNL 336
gi 313231660  107 VATNSTQLLVQ-NIASIKQ-E-------------KFNA----KEHILKSEV-LKKSVRD---KAVQELNYDPYDKIYKDL 163
gi 762076526  312 PEYNSTLRMRK-EIESIKE-S-------------HVDVVKALDKKLQISDT-VSSDIRE---KASTKVNVSSPR--FTGL 370
gi 358337957    3 VIFTAELSFDHlHFQEPCErA-------------RKEAARLVEEACAGSSQsNAESLLL---TPGLTVNIPEDVCTFNNL 66
gi 321479253  120 PIFQSSVVLMK-NLETLKN-L-------------EIETRNLLSHKVEKDKK-MQKLLNS---KVSTVLN--PSRQIFSRL 178
gi 156363641   83 PCVNSSARISH-KLQMLQE-C-------------KFNSAIAIAAELEKSET-TKTALLE---RAALGVNVKRDQNKYSDL 143
gi 170056990   75 PELHTALNVQK-QIEKVQG-A-------------KVKAPASIGELTPKS----QKFVRN---QITRKLNFQHDDNVFKGL 132
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350646355  262 IDLTVDESEIVRLErqriAAQRKRLLEANRKQNI-----KVDe-----PEPDLLEFFDp---NRHVYQSVN--L---QSK 323
gi 260790797  241 VSLDVPVQRVLEAA----VEEKLSMVKDVRHERP-----QVQ------EEPDIMDFFT----DDLMFESAD--Y---STT 296
gi 1043402188  83 LSVEPPAGQV----------QRLSERPRRAEPKEapqlqAPQl-----QAPDLSAFSHl---CERFTETPC--L---TVE 139
gi 198417578  337 VSLDVSSGDIA-AT----TQFRRIKRPSFTKLGP-----S--------EEIQIMDLFPp----DLIQEKVI--V---ESK 389
gi 313231660  164 MGLDVNKENLIEQE----IKDRLGRVEKVEMAKA-----IKCs----yGEPNIRDF-------EYMEQTSFgsL---TMK 220
gi 762076526  371 VSLSVPVEDI--------------DKPQTFRAKP-----VKArsqsktQEPDLMEFFS----TEFQRETPE--L---STP 422
gi 358337957   67 MELTVDESEIVRLErervANQRKHMAQLRKKAAK-----QKPv----fPAPDPLEFFDp---NQHVFQSVN--L---HVR 129
gi 321479253  179 QPISFNVEQLVDQDetrlHNLAEKNAPQMRYRD---------------PEIALKDFID----CMVISKTPI--L---PES 234
gi 156363641  144 VPLDLVAEDLIGVH----TQQRASFKPREPKVPD--------------NEPQIMDFFSe---EFEEETSRC--VfpgPEE 200
gi 170056990  133 VPVNVNDSVLIPa------RKRPLRSKFVAKEKR-----D--------PEPELADFLRpiakCSIEFEPYL--------- 184
                         170       180
                  ....*....|....*....|....
gi 350646355  324 GIRSLLPTLHCAS-DdLVNVFQHK 346
gi 260790797  297 HIPSVTASLQIAPpHmTFDLYRHM 320
gi 1043402188 140 GPPPVVICPRPRPaHsVFDMYHKL 163
gi 198417578  390 CYSLPTLSTVTTPlDsVMSLYEHs 413
gi 313231660  221 NHAFHLPQIEDEPsItASEVYEKI 244
gi 762076526  423 GLSTPSEPLVTASpMsAFDLYRHN 446
gi 358337957  130 GLPSFLPSAQRASdDsYMAIQERM 153
gi 321479253  235 SFHDQCCQFQINPfIqhqipgnnn 258
gi 156363641  201 VDNEVDDDDDGGGgGhAFDLYRHV 224
gi 170056990  185 -------PPEPAPrRpNFDNFAHI 201
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