Conserved Protein Domain Family
Ntox50

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pfam15542: Ntox50 
Bacterial toxin 50
A predicted RNase toxin found in bacterial polymorphic toxin systems that is proposed to adopt the BECR (Barnase-EndoU-ColicinE5/D-RelE) fold, and contains two conserved histidine, a serine, two lysine, and a threonine residue and a HxVP motif. In bacterial polymorphic toxin systems, the toxin is usually exported by the type 2, type 6, type 7, and MuF-type secretion systems.
Statistics
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PSSM-Id: 317879
View PSSM: pfam15542
Aligned: 24 rows
Threshold Bit Score: 88.5932
Threshold Setting Gi: 122375182
Created: 30-Jul-2016
Updated: 4-Aug-2016
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81454854  313 VNPEKQARHIKSTAGE--GK-----------SYFF-DDVDTDVLYQKYKQTGEL-IKNRRGR-THKELIDLPEDISIGID 376
gi 122448245 121 INPEKQALHMESTKLE--GK-----------SYLY-DSEDPQELLDKYAGKGHI-NKNKKGLwDNREVVEVDHIVGVDYN 185
gi 122539650  11 LNNVKQKRHILCTNEYnnKKnnss----llpSYTIiDSNESEKMTKKEFIDIPV-LFDDEGNfRIKQVIDYKKIIGKSYv 85
gi 81674860  346 LNNEKQERHILNTKAYynKKynss----ilpSYITlDTKEIEKITKKEFINFPV-LFDDEGKfRNKQIINYNKIIGKSYv 420
gi 524500550 157 INDGKQGKHIKGHNNYieGR-----------SYIIiSSEEVQKLINKYAGTGML-IRTKNGKwAKQEVITTNTLIGYDVN 224
gi 524702632 429 INQGKQDKHIIGSNNYidGK-----------SYLTiSKEKAQELINQYAGKGQL-EFSDSGKwNKKEIITVKETIGVVKN 496
gi 739689026 342 LNPNKQNRHQLGHQLYedYKkknlqkgkampSYTIlENKQLDSLLSQKIGKGRL-LTKRNGEwKNKEVIDFGEIIGNDYm 420
gi 323464108 340 LNVEKQNRHQLGHQMYedYKkknlqkgkaipSYTLlDNSELNSLIHQKAGKGSL-IADDFGNwKNKEIIDFGKIIGKDYi 418
gi 488932446  73 IHEGKQGKHIVGHNNYd-GK-----------SYLA-EEVDPQELVDAYHGTGDYkITSPNKNwVKKEFVFGKDTMEFVVD 139
gi 521293553 358 YSIQHYNKHKEGTKQYeqYKqsrlkkgqteqSSLLiSYDEAKEIIKKYAGTGVF-SRDRKGKwRNEEFVDVDSIIGVVHN 436
                         90       100
                 ....*....|....*....|....*
gi 81454854  377 iysgNLV--NGLTIHYGKTGSHIVP 399
gi 122448245 186 ----SGMktRWIKIHHSKKRTHIVP 206
gi 122539650  86 n--gKYIetKLGKVHYSKTGFHVVP 108
gi 81674860  421 n--dEYIetKLGKVHYSKTGFHVVP 443
gi 524500550 225 disgAETatKAFKIHYSNKGTHIVP 249
gi 524702632 497 k--nNEIktNSFKIHYSKTGTHIVP 519
gi 739689026 421 d--gEWKetKFGTVHYSKTGTHIIP 443
gi 323464108 419 d--gEFIetKRGTVHYSKTGSHIIP 441
gi 488932446 140 evirEVTptRYFSIHYSNEGTHIVP 164
gi 521293553 437 id-gTVTptNRIQIKYGKNSVHIVP 460
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