Conserved Protein Domain Family
FSIP1

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pfam15554: FSIP1 
FSIP1 family
Statistics
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PSSM-Id: 317888
View PSSM: pfam15554
Aligned: 16 rows
Threshold Bit Score: 323.961
Threshold Setting Gi: 156382621
Created: 29-Jul-2016
Updated: 4-Aug-2016
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74729808     2 DIIKGNLDGISKPASNSRI----------------RPGSRS-------------S------------NASLEVLSTEPGS 40
gi 81881362     4 DIIKGNLDGISKPASSSRS----------------RPGSRS-------------S------------NGSLEVLTPEPGS 42
gi 611969925    2 DIIRGNLDKISRPASNSRI----------------HHESKT-------------S------------STSLEVLTPEPVT 40
gi 327280153    2 DITRGSLDEISRPASNSRI----------------NNGNKV-------------L------------STSLEVLTPEPNL 40
gi 115840533    2 DITRGSLDDITRPARNSRY----------------RPGSRV-------------SlnspvnrslsvaSSSLELLPPDPDI 52
gi 260836895    2 DITRGSLESITKPARSSRSrpdsrvslssassrrsYTG--T-------------S------------MGSLEILTPEPPL 54
gi 512862766    2 DITKGSLDMIARPASSSRS----------------RPGSRVstslsterlkrssT------------SLSLEVLTPEPGF 53
gi 971400716    2 DMAKGSLDKILQPASSSRA----------------YPSCRH-------------L------------SVSVELLAPEPCL 40
gi 1040194204   2 DIIKGNLDGISKPASSSRT----------------HPGSRN-------------S------------NASLEVLSPEPAS 40
gi 344294152    2 DIIKGNLDSISKPASSSRK----------------HAGSRG-------------S------------NASLEVLSPEPGS 40
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74729808    41 FKV--------Dtasnln--------------sgkedhSESSNTENRRt--------SND-------------------- 70
gi 81881362    43 VKI--------Dmvnkln--------------sgqeghTSNSGVEERRn--------SND-------------------- 72
gi 611969925   41 LKV--------Dtsinlns-------------csqqskRENCNSRESSsssnvgkklSSQ-------------------- 79
gi 327280153   41 PKV--------DfynnytedeseknyekgeedgikkmkSSQEISEENAn--------NGFqlviqnenq--------vee 96
gi 115840533   53 LLQ--------E--------------------------DNDLAVVEFLn--------SSE-------------------- 70
gi 260836895   55 LQY--------Eeedie-----------------------------------leeylSSD-------------------- 71
gi 512862766   54 SEMqclgldthEtqlearr-------------ktpirhQERLPEQKHLp--------KNStesyeecirdem---dfepp 109
gi 971400716   41 PKV--------Dspvslgv-------------yhrrslEGCCPEENRGd--------GGQnsdikevervtffqecvldp 91
gi 1040194204  41 FQI--------Dtaikln--------------sgkedqPESMDTEERGn--------IND-------------------- 70
gi 344294152   41 FKV--------Dtaikln--------------sgkeghSES--TEESRn--------SDN-------------------- 68
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74729808    71 ------D---------------------KQESCSe-K---------------------IKLAEEGSDEDLDL-----VQH 96
gi 81881362    73 ------A---------------------KWADDS--K---------------------TKPAKESSDEDPDM-----PQP 97
gi 611969925   80 ------DiktsqdycsevdcslreeiksSCTNYSghN---------------------SSLNSSKEDNEVDYfslydVPQ 132
gi 327280153   97 cssspmD---------------------SENDCTenQ---------------------LYSCSNAPQKKLAK-------L 127
gi 115840533   71 ------D---------------------EEVGNGeeEdindfgrsggvfnacrvqdrlHNLDLLLLAKGDNE-----SMD 118
gi 260836895   72 ------D---------------------SANESGeeS---------------------ARYRLSSELSDVPQ-----YDR 98
gi 512862766  110 fptketD---------------------HLFDEAedD---------------------FLDFPSAEFEDTGEn------D 141
gi 971400716   92 ryvsnsD---------------------SGDDNTeaQ---------------------TSVSCEPSQGKT---------R 120
gi 1040194204  71 ------D---------------------NGEHFSe-K---------------------TKLAKEGSDEDLDL-----VQC 96
gi 344294152   69 ------E---------------------KGENFLe-T---------------------IQLADVGSDEDLDF-----VQH 94
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74729808    97 ------------------------------------QIISECSDE-PKLKE----------------------------- 110
gi 81881362    98 ------------------------------------QATPEHSDD-PKLEE----------------------------- 111
gi 611969925  133 ------------------------------------EMSGQVKEEiSRIKE----------------------------- 147
gi 327280153  128 ------------------------------------QKVTAKSTNiGNSTE----------------------------- 142
gi 115840533  119 ------------------------------------GSLPDTDDP-SNLRElthlnrtdedrsgrsssrgrrsenresrq 161
gi 260836895   99 sgalslgrqmeeaykagveaaqksiaasqlipigreNGTPDDDDD-VSLNE----------------------------- 148
gi 512862766  142 ------------------------------------DEVPNDEHDfVNDKA----------------------------- 156
gi 971400716  121 ------------------------------------NAKEANSSKlLDSEE----------------------------- 135
gi 1040194204  97 ------------------------------------QIIPECSDK-PKLEE----------------------------- 110
gi 344294152   95 ------------------------------------QTIPECSDE-PKLNE----------------------------- 108
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74729808   111 ------------------L---------------------------D--SQLQDAIQKMKKLDKILAKKQRREKEIKKQG 143
gi 81881362   112 ------------------T---------------------------N--AVLQNAIRKMHRLDKLLAKKQCREKEVKKQG 144
gi 611969925  148 ------------------S---------------------------D--VQLQEAVEKMKRLDKVLVEKQFKEREIKKQG 180
gi 327280153  143 ------------------K---------------------------DvdPLVLNAIKKMKRLDQILANKQSQERAIKKQG 177
gi 115840533  162 dveeeeeeedpdadlaaiT---------------------------D--PELKKAIKKMRKLDRILNTRVTREKEVKRQR 212
gi 260836895  149 ------------------SgtdsplpitdgqdegegggdgtdesteD--PKLRAAIKKMEKLDRILAKKMLREKEVKRQR 208
gi 512862766  157 ------------------T---------------------------D--PKLERAIKRMQALDNILQRKLAKEKEVKAQG 189
gi 971400716  136 ------------------Te-------------------------gD--PQIQAAIKKMHKLDTILAKRHVKERAVKKQG 170
gi 1040194204 111 ----------------------------------------------D--SQLQDAICKMKRLDKILAKKRCREKEVKKQG 142
gi 344294152  109 ------------------L---------------------------D--FKLQDAIKKMKRLDKVLVKRQDREKEVKKQG 141
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74729808   144 LEMRIKLWEEIKSAKYSEAWQSKEEMENTKKFLSLTAVSEETVGPSh---EEEDTFSSVFHTQIPPEEy--EMQMQkl-- 216
gi 81881362   145 LEMRVKLWEELKSAKNTEDLENDEELGNTKKFLCLTSESAGKAAAEalhcEFEDALFSVFHTQIPPETy--ENLME---- 218
gi 611969925  181 QEMRIKMWEELQTIPNFDAIQNNEEIENTKKFLSLASSSEGTTDFHh--lEQEEPCVSVFHTQIPPEDy--ENCVEqa-- 254
gi 327280153  178 KELRRKLWEEFQFTTSPSSTVITEEGENTSRFLALESPLPETLDSSa--vEEDEVFVSLFHTQINPENy--AHSGRet-- 251
gi 115840533  213 KMLHYQLEVELEAIKEEGGGKSKEASENTTRFLALVPPVSHDEGVN----MEDIPSTPVFATQPPEGSs--PSHKTssss 286
gi 260836895  209 MDLFKRLKDEMGDIKPEGRDEQKEVSHNTMKFLALAPPESHNQVVY----EENPEFVPVFQTQA-EEDg--RSTASsgqs 281
gi 512862766  190 LEIHIKLWEELQRATTQSSARSHEESINTSKFLALTPQLDETEDTVn--mQMGKIFSPVFPTQLPNEDpaeDDDHEtl-- 265
gi 971400716  171 KEMRAKLWEELKSVSTMG---IHEEIENTKLFLTLISSWQDATDPSh--vKQDETHALLFHTQISPEDy--AFHKAqh-- 241
gi 1040194204 143 LEMRIKLWEDLKREKKGEAFQSNEEIENTKKFLSLTAASEETVDPSh--yEDEGTFFPVFHTQVPPEEy--ENHMHsv-- 216
gi 344294152  142 LEMRIKLWEELKSAENSDALRSNEEIENTKKFLALTAASEETV--DpscyEDEGTFFPVFHTQVPPEEy--ENHVty--- 214
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74729808   217 ----------nKDFTCDVERNESLIKSGKKPFSNTEKIELRG-----------KHNQDFIKRNIELAKESRNPVVMVDRE 275
gi 81881362   219 -----------KDFTCDVEKNEPLIITEKQPFSNTEAIEPRSedsqgfirqnaEHSQDFIKRNIELAKHSRSPVVMVEGE 287
gi 611969925  255 ----------rRESVYHSESNKSLIKAEKK-LQRENSGEFKS-----------KKNQDFIKRNIELAKDSKNMVIMMDKE 312
gi 327280153  252 ----------kQDCLSEDRTRSTMKTIENMHQKSEASY---------------KNYPDFIKKNIELAKDAANQVVMLEEE 306
gi 115840533  287 ehsspgrtvgqSRRASKTSPRDHLRRPRPPGASNQGRKE---------------DEPDFIHRNIQLASDAGNLIAMTDDE 351
gi 260836895  282 sr----ttsqqSSVAGAASGKEDQRRRRRSKKQSRSKGEGSGd----------KEKPDFIKRNIQLASDANSLIAMTDDE 347
gi 512862766  266 ----------kDDMSGDSSHRSDCRTRQSKGQMKG---------------------VDFIQRNIELAKDAGSYILLMDDE 314
gi 971400716  242 ----------nKDYPSEIETNKFLNQAEKTTQNKS------------------KNSQRFIKKNVELAKDSGKQVPMLEGE 293
gi 1040194204 217 ----------nQDFTHDVERNDSLVKAEKKPFSNIEKTELRG-----------KHNQDFIKRNIELAKNSRDLVVMTDEE 275
gi 344294152  215 ---------asQGFTYDVERNESLIKSDKKPSSTTENIELRG-----------KHNQDFIKRNIELAKESGNPVVMIDKE 274
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74729808   276 KKRLVELLKD--L--D--EKDSGLSSSEGDQSGWVVPVKGY-ELAVTQHQQLAEIDIKLQELSA----ASPTISsfsprl 344
gi 81881362   288 KKRLDELLQG--L--D--DADSGLSSAEGDQCGWLVPGEGY-TLAATESQQLAEIDIKLQELSV----DSPTIFsle-sq 355
gi 611969925  313 KQRLTELLSD--I--D--KGKDLSPRTQSYESAWPMLEKSYlSTAHMERKQLAQIDSKLQDRFSf--sSS-WISsgylgm 383
gi 327280153  307 KKRLAELLRD--T--E--EETNELNVTEKEVMGWLVPGEGY-TPEPVEYHHLAEISAKLKAVISdgdyAAVDNSle---v 376
gi 115840533  352 KKRLEDMLSEvvV--L--AGEPDEGSSGNSLQLKHIPGSGY-TPDADSQMLLQDIDEKLKNLLPsddfMDICSTpsmlgd 426
gi 260836895  348 KKRLEELLEN--I--DteDDSQAADTPVNPFQLALVPGTGF-TPEEDDMKALRDIDSKLQVLLPphdyESICST------ 416
gi 512862766  315 KLRLEQLLED--IqeD--CSDEDIT---GDMSSWIVPGEGY-TPEPDEYDQLAEIEARLQRVRGn--eESLETSlsdpki 384
gi 971400716  294 RKRLIELLKD--T--E--DGST-LQDLEEDVCGWLIPGEGY-TPEPMEFHHLNEIDRKLQILLSngdfSAISSScs--np 363
gi 1040194204 276 KKRLVELLKD--L--D--DQDSVLPSCEGDQCGWLVAGDGY-TLAPTQHAQLAEINTKLQELSA----TSPTMPsffarp 344
gi 344294152  275 KKRLVELLKD--L--D--DGDFGLSSSEGHQSGWLVPGEGY-TLAVSEHRQLAEIDTKLQEFSA----ASPAISnfaprl 343
                         650       660       670       680       690
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 74729808   345 ENRNNQKPDr----DGERNM--EVTPGEKILRNTKEQRDLHNRLREIDEKLKMMKE 394
gi 81881362   356 SHKGDMECDa----NEERNT--EPTPGEKILRDRKEQRDRESRLRAIDGKLKELSE 405
gi 611969925  384 DNHIGQETDp---nDKKR-A--KMYPGDKTLRNNRDYRYEKNRLKEIDQQLKDLEK 433
gi 327280153  377 PSQIYQESl----aYANRKL--ETIPGEKVLRGTKEERDQQNRLKEIDQQLKILEE 426
gi 115840533  427 RRESFNPA--------------AFDLGERILKDTKIEQSQQQRLKNIEQELVSLQN 468
gi 260836895  417 PRNFDIQNDelfqmTDLRSSldVMQLGERVLRDTRQVRDQQHRLQDIERELEELQT 472
gi 512862766  385 PKEIFQEVl----lEKNGNS--HSAPGELVLRYTKELREQKMRLREIDQQLQDMGR 434
gi 971400716  364 PSQIYQESl----vYANRSL--EVVPGEKVLRDNREYRDQQNRLKEIDHQLKSLER 413
gi 1040194204 345 DSQNEQEPGl----DEERNK--EITPGEKVLRNTKEERDQQNRLKEINEKLRKMKE 394
gi 344294152  344 ESQNDQelv---lnDDGRRT--EITPGEKVLRNTKEQRDQQNRLKEIDEKLRKMKE 394
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