Conserved Protein Domain Family
CT47

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pfam15623: CT47 
Cancer/testis gene family 47
CT47 is a family of proteins found in eukaryotes. Proteins in this family are typically between 262 and 291 amino acids in length. There is a conserved HIL sequence motif. The function of this family is not known.
Statistics
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PSSM-Id: 317935
View PSSM: pfam15623
Aligned: 11 rows
Threshold Bit Score: 165.804
Threshold Setting Gi: 529013554
Created: 29-Jul-2016
Updated: 4-Aug-2016
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 296236323   1 MSATGDPDPTQGDQEALVSQEGAQVEVAGagdWEGIDP------------------------GPNSGFVVP---VAEVAG 53
gi 537133019 421 MSNPGNQDPTKESRDNPVTLQGEWVREAA---EAGLAS------------------------DLDAASASP---AVEVMA 470
gi 351709901   1 MSASGNEDPTPNDPDSPVSPAVEWAVAAGvreGKGPDS------------------------GTGGGGAAQ---ATCEAQ 53
gi 967506982   1 MSATGDRHPTEGDQEAPVSQEGAQAEVAGagnPEGGDS------------------------GPHSSDMVP---ATEVVG 53
gi 426397309   1 MSATGDRHPTQGDQEAPVSQEGAQAEAAGagnQEGGDS------------------------GPDSSDMVP---AAEVVG 53
gi 532067443   1 MSATGDRDPT---QEGPV---GEWMGAAGvgeGIDLDL------------------------GPDEGNMAPetmEAEVAG 50
gi 831237915   1 MSSTGDGDPTQEGQESPVSRVGALSRARGahhGVGRDS------------------------DPDEGNMAP---VAEAAG 53
gi 529013554   1 MSTTGDGDLAPGGQEGPAGVAGAQV---GardGVDHNS------------------------EPHRGDSMPeaeAGGVVG 53
gi 675719181   1 MSATGDQDPIQEDQEAPVSQEGAQAEAGGd--REGGDS------------------------GPDSGN--------TVAG 46
gi 967506904   1 MSATGDQDPIQEDRKAPVSQERAQAEAGGd--REAGDS------------------------GPDSGDMVP---VAEVAG 51
gi 675769488   1 MSATGDPDPPQGDQEALASQEGVQIEVAGagnQESSNSdpnsgdvvptaeaagagdgeggdsGPNSGDVVP---TAEVAG 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 296236323  54 D-------AG-----P-MEGlSVEEGEQAAGLpaapgdrSVEEDSDIELLeeeeEEEEE--------------------- 99
gi 537133019 471 VhrrevenVG-----P-ERN-PEEEGYRRESV-------DAEQDSDIGPV----EEEEE--------------------- 511
gi 351709901  54 V-------TE-----PgLAGeVVRPEARSLCFsslpsmgPAEEEPQEEVE----EEVRD--------------------- 96
gi 967506982  54 V-------AG-----P-MEGlREEEGEQAAGLatvpgggSTEEDPDIGPA--------Aeeeeeeee-----------ee 101
gi 426397309  54 V-------AG-----P-VEGlGEEEGEQAAGLaavprggSAEEDSDIGPAteeeEEEEG--------------------- 99
gi 532067443  51 S-------GGmeileP-EGGlEEEEGAQGLVParareggNTEEDSDIGPA----EDEGG--------------------- 97
gi 831237915  54 V-------AG-----P-EGGlREEEGDQEEAParapegdSSEEDSDIGPA------EEE--------------------- 93
gi 529013554  54 V-------SG---------------GPREVALvg----aNAEEDSDIGPAe---DGEDG--------------------- 83
gi 675719181  47 V-------AG-----P-MRGlGEEEGEQAAGLaaapgggNAEEDSEIRIVeeeeEEEER--------------------- 92
gi 967506904  52 V-------TG-----P-TRGlGEEEGEQAAGLaaapvvrNPEEDSEIRIVv------EMveeeeeeeeeeeeeeeeeeee 112
gi 675769488  78 D-------AG-----P-MGGlREEEGELAAALws----gSAMEESYIGMVevevEMEEE--------------------- 119
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 296236323 100 -----EEE-----------------------------GeadlNLNLIMVPHRYPMMGVRFVLLDLVQSLYRRLYQNDHII 145
gi 537133019 512 -----GEA-----------------------------EanvtADLRLVDAHRFPMAGFRFMFLDLIHAILNRVYYNDHIL 557
gi 351709901  97 -------------------------------------C----GANQVVDARQFPLVNFQISFLDLVRSHLQRIYYKNHVL 135
gi 967506982 102 eeeerNVA-----------------------------G----NLDLAEVTRRFPAAGIRFVFLDLVHSLLRRLYHNDHIL 148
gi 426397309 100 -----NEA-----------------------------A----NFDLAVVARRYPEAGIHFVLLDMVHSLLHRLYHNDHIL 141
gi 532067443  98 -----DLA-----------------------------E----SQDILVDARQFPMVGFRFMFLDLVHSLLHRIYYNDHIL 139
gi 831237915  94 -----EVP-----------------------------GlpmlGLDMMVDAHQFPMAGFRFMFLDLVHSLLHRIYYNDHVL 139
gi 529013554  84 -----EQA-----------------------------E----GVNRMVDSRHFPMTGFRLTFLNLVHLMVNRL-SDNHIL 124
gi 675719181  93 -----NEA-----------------------------D----NFDLVAAARRYPLRGFRMEFLDMVHSLLLRIYHNDHIL 134
gi 967506904 113 eeeerNEA-----------------------------G----NFDLVAATRRYPIIGFRVEFLDMVHSLLHRIYHNDHIL 159
gi 675769488 120 -----SESdeeeeenveeeeeeeeenreeeeeeeedeD----NFGMVAAARHYPIVGFRLQFLDMVHNFLHRIYHNDHIL 190
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 296236323 146 IGPRHrSRLMAmarA--------A-----------ALNRS----GDPHWLLAPQRL-G-VGIP-GPEGH------GLGLI 193
gi 537133019 558 IRRPCeNPVME---T--------P-----------GPSAS----GHSSMLQILPGP-TpSTLR-AAEYEaqasglTRSLP 609
gi 351709901 136 IHPYW-NALMLqprP--------PrsashlgpgpdPDPGP----SELPVLHMLPWPrG-VAPR-QDEGQd----eDEGQP 196
gi 967506982 149 IATRHhSRLMVgprA--------A-----------APNRR----VEPSLLLLLQRL-G-AGAA-ALEGQ------GLGLI 196
gi 426397309 142 IENRHlSRLIVgphA--------A-----------APNLW----GNLPLLLLPQRL-G-AGAA-ARAGE------GLGLI 189
gi 532067443 140 IRPYR-GPVVVrsrS--------P-----------MADGS----SELPVLHIPQRP-R-MRAQ-SREVQdeglrlGLGLP 192
gi 831237915 140 VRPLG-GRLVVrhhP--------H-----------GPDGGnvaiEIPVVLHVPPRp---HVRApAQEGE------Gpsgl 190
gi 529013554 125 VRRNY-DHVSVrhqTrprlsdfgS-----------A-----------------------AMAG-FSEVQvpsyesGEGLA 168
gi 675719181 135 IRMRG-GRLMRrrrT--------A-----------APSGS----EEPRLLLVHERL-G-VGAA-GPEGE------GLGLL 181
gi 967506904 160 IGMRG-GRLMRrprT--------A-----------APSGS----NEPALLLVRERL-G-VGAM-GPEGE------GLGLL 206
gi 675769488 191 IRFRG-SRLMVgphP--------V-----------MPSSD----EPP--LLVSERL-G-AGAR-APESD------DLGLI 235
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 296236323 194 QEAASV---P---EPMVLADPAEM--------AG-------------------E------------PAE-ESAE------ 221
gi 537133019 610 EVISTF---PeleEPADYEEIAERylpaphlnMQ-------------------E------------PAV-RAAV------ 648
gi 351709901 197 EAVVSI---PdleEGDPTAVLALT--------SE-------------------E------------PLK-ETAK------ 227
gi 967506982 197 QEAASV---P---EPAVPGYLAEM--------ARepteeaaeepveeareeeaA------------E---EATE------ 241
gi 426397309 190 QEAASV---P---EPAVPADLAEM--------AR-------------------E------------PEE-EAAE------ 217
gi 532067443 193 EVATSVlefQ---EPTDNAEAAHV--------SV-------------------E------------RTE-EVAE------ 223
gi 831237915 191 hhlaeaaavaaaqeaegqepaaaeepareaaeepareaaeepareaaeepareaaeepareaaekpareateepacrase 270
gi 529013554 169 EEALAQe--A---EQAEEAQEAEQ--------AE-------------------E------------AQEaEQAE------ 198
gi 675719181 182 QEAALV---P---EPEVPADLAEM--------AR-------------------EpaeepaeeasekPTE-EAAE------ 221
gi 967506904 207 QEAASV---P---EPEVPADQAEM--------TR-------------------E------------PAE-ESS------- 233
gi 675769488 236 EEAEVV---P---EPEVPANLVEM--------AR-------------------E------------PEE-EPAEeaaegk 269
                        410       420       430       440       450       460       470
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 296236323 222 ---EAAEEPPAEGpateelaaeel----------------aaeepaaeeaTAPKEVTKSQPEKWDEEAQD--AADE 276
gi 537133019 649 ---VEPAEQAIEE-------------------------------------VAPEAIAEEPEKEVIEQIMT--SEGE 682
gi 351709901 228 -----SREQMADSkg----------------------------------kEWMEAVSENLLENRRDDDED--VGGe 262
gi 967506982 242 ---EEATEEKPaeeatee--------------------------paaeeaTAPEEVTKSQPEKWDEEAQD--AAGE 286
gi 426397309 218 ---EKLSEETTEEpdaeepat---------------------eeptaqeaTAPEEVTKSQPEKWDEEAQD--AAGE 267
gi 532067443 224 ---EEQAEEMIDqv-----------------------------------tEIRGEewv------------------ 243
gi 831237915 271 apaheaaeeptrgpaeeatkevaegaseepacpaaeeaeeklpvlvtnaseitkpdhkeeldednkgkeekqakke 346
gi 529013554 199 ---EAQEAKAPEEaslwetatkese--------------epslrempqepVAPEKTAECQDENSKEEGQGtkSEGK 257
gi 675719181 222 ---EELAEEAAEEpakeepaaeee----------------saeepateeaAAPEEVTKYQHEKWDEEAQD--AAGK 276
gi 967506904 234 ---EEASEEHAEEaaeeelaeea------------------aeepateeaAAPEEVTKYQHEKWDEKAQD--SAGE 286
gi 675769488 270 psgEEPAEEAVPKeeaatqepaakklateeepedkpaaeesaeepatqeaAAPEEVTKYQYEKWDEEVQG--AAge 343
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