Conserved Protein Domain Family
CEND1

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pfam15677: CEND1 
Cell cycle exit and neuronal differentiation protein 1
This family of neuron-specific proteins may have a role in the differentiation of neuroblastoma cells and neuronal precursors. It is involved in development of the cerebellum.
Statistics
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PSSM-Id: 317980
View PSSM: pfam15677
Aligned: 7 rows
Threshold Bit Score: 83.8691
Threshold Setting Gi: 821493479
Created: 29-Jul-2016
Updated: 4-Aug-2016
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 8134343     1 MESRGRSANSPKADAKa---tTEARAPPAVDGKVP---SAK--KQEAQkaEKqePPAAPTLPPAKK-TSA-----LLDNH 66
gi 637246846   1 MESKGSIRSGNKADAK-----AAGLGKPEKPSSGP---TATtdKKETS--SK--EPSAPATNPVKKgVPAanessMLNDH 68
gi 821493479   1 MEAKGRATSGPKSESK-----PSPAPAAPSAKAe---------KKETP--EKreQPSTP-PAPPKK-AQApadpaLLNSH 62
gi 354495385   1 MESRGKSASSPKPDTKmpqatAEAKATPAADGKAP---STKpvKKDTQt-EKqeQPTAPGPATTKK-TPAkadpvLLNNH 75
gi 733887756   1 MDSKGNVRSGNKPDAK-----APSSGKPEKPSPGP---ATNadKKDTPk----eQPN-PATA-TKK---AgsdaaVVNNH 63
gi 344309219   1 MESRGKSASSPKPDTKapqapAEPRGPPAADGKAPgaaSAKpgKKEGPv-EKqeQLAAPTPAPAKK-TPAkadpaLLNNH 78
gi 297687784   1 MESRGKSASSPKPDTKvpqatTEAKVPPAADGKAP---LTKssKKEAPa-EKqqPPAAPTTAPAKK-TPAkadpaLLNNH 75
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 8134343    67 SNLKPAPAA---PSSPDAAP-EPKGPGDGAEEaeapSggPGGrGPCPFENLNPLLVAGGIAMAAAALILGVVFLARKK 140
gi 637246846  69 SNIKPSPVAsegAEAAARTPaDSEHQANNTEE----S--PGG-GCSIFENMKPLIVFGGVAVAAIAVIVGVAILARKK 139
gi 821493479  63 SNLKPNPGAapaPSPPDES--EPKGPGDGAEEegvaS--PAG-GPSTFENLKPLLLAGGVAVAALAVILGVAFLARKK 135
gi 354495385  76 SNLKPAPAVpaaPSSPDATS-EPKGPGDGAEEdesnT---GGrGPWPCENLTPLLVAGGVAVATMALILGVVFLARKK 149
gi 733887756  64 SNLKPSAAAtetQEATGQSP-DSDHKGNGSEEs------PG----SIFDNMKPLIIVGGVAVAALAVIVGVAFLARKK 130
gi 344309219  79 SNLKPAPAA---PSSPDATP-EPKGPGDGAEEdeagSrgPGGqGPCPFENLTPLLVAGGVAVAAVALVLGVAFLARKK 152
gi 297687784  76 SNLKPAPTAptvPSSPDATP-EPKGPGDGAEEdeaaSggPGGrGPWSCENFNPLLVAGGVAVAAIALILGVAFLARKK 152
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