Conserved Protein Domain Family
DUF4685

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pfam15737: DUF4685 
Domain of unknown function (DUF4685)
This domain family is found in eukaryotes, and is typically between 106 and 131 amino acids in length. There are two conserved sequence motifs: SGE and VRF.
Statistics
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PSSM-Id: 464834
Aligned: 17 rows
Threshold Bit Score: 119.49
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_007480965  322 RALVSSQQLSLSPRHEQANQLLQQARMKAKTSPLRANHDIVPSMAHRLpaRDVSSGTIQTPRVTLACREGdvpysgsLSD 401 
EHA99933       71 CQFLPDLQDQLSGFQERLEKILHQ--RTSSLGQLSGDHSQFPTVRKAS-----SFCGTPAPEAM-------------PTP 130 
XP_014972129  176 CSFLPDLWGQSSHLQDSLTKILLH--QTPTLGSLKGHHSQFTTVKKAN--HRPHGAQVPKLKAA-------------LTH 238 
XP_009002416   49 RSFLPDLWGQSPHLQDSLTKILLQ--QTPALGSLKADRPQFSTVRK-------------------------------ASH 95  
XP_008697107  105 CSFLPDLRGQSSYFQNSLKKILLH--QIPTLGTLRRDHSQF-TLKKAN--HRPHGAQAPKLKAV-------------LTH 166 
XP_002691719  198 SHFLPELGGQSSYLKNSLKKILLH--QIPALGPLSRDYPQFTTVKANQ----PQATQAPKLKAV-------------LTH 258 
XP_007664167   19 RACVPSQELVLSPQSEQAKQLLQRGRMKARTGPLRASHDILPASVPHQ--RFAGGDPAPEPRMTSAPRDGdgshggnLSD 96  
EHB09817      275 RTFGPKPEAVLSTRHEEAKHLLQHPRMKARTRPLRASHDIVPAIAQGS--RDGRRSPALGPRMTLACRDSpqs--gsLSD 350 
XP_023404908  351 RTSGPKPETGLSPRCEEAKHLLQHARMKARTRPLRASHDIVPTIASGS--RDHRRSPALDPRVTFPSRDSpqn--gnLSD 426 
XP_014341089  362 RAFVSSEEPTLSPRHEQAKRLLERARMKARSSPLKADHSILPLKKDCCp-RQSHGSGVHA---VKKTRNEspplsgnLSD 437  coelacanth
XP_007480965  402 SSSGDsinDQRRKRGLSP-SRVRFEDESAQDAEVRYRERLQQPQKRALDS 450 
EHA99933      131 TPSGE---GLGPRRHSCP-FQVRLADEMLTDSALCYWEHSCAVQQSRMSP 176 
XP_014972129  239 NPSGE---GSKPRKRRCP-FRVRFADETLQDTTLRYWERRCSVQQSVIVN 284 
XP_009002416   96 RPSGK---GSGPHRPRCP-FRVRFADETLQDTLLRYWERQCSVTQSVTVN 141 
XP_008697107  167 SSSGE---SSGQRRRGCP-FRVRFADETLRDTALRYWERSCAVRQGTIEN 212 
XP_002691719  259 NSSGE---GSGHRRRCCP-FRVRFADETLRDTALRYWERSCAARQGIFEN 304 
XP_007664167   97 SSSGEsgcGQPRKRGLSP-SRVRFEDESTRDAEVRYLDRMQQRQRRMLDS 145 
EHB09817      351 SSSGEsgsGQWPKQGMST-SHVRFEDEPAFEAEFRHLKRLQQRQRQVLST 399 
XP_023404908  427 SSSGEsssGLWPKQSASPlSHVRFEDESAGDVESRYLERQQQRQRQVLNS 476 
XP_014341089  438 SSSGEsncGLQKKRGQSP-TRVRFEDESARDAEVRYWEREQQRKKGTLDL 486  coelacanth
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