Conserved Protein Domain Family
TMEM215

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pfam15746: TMEM215 
TMEM215 family
This family of proteins is found in eukaryotes. Proteins in this family are approximately 230 amino acids in length.
Statistics
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PSSM-Id: 318043
View PSSM: pfam15746
Aligned: 6 rows
Threshold Bit Score: 370.684
Threshold Setting Gi: 512813846
Created: 29-Jul-2016
Updated: 4-Aug-2016
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74748275    1 MRPDDINPRTGLVVALVSVFLVFGFMFTVSGMKGETLGNIPLLAIGPAICLPGIAAIALARKTEGCTKWPENellwvrKL 80
gi 557018456   1 MRQDNINPRTGLVVALVSIFLVFGFMFTVSGIKGETLGDIPLIAIGPAICFPGVAAIVLAKKTDGCTKCPCG------KS 74
gi 972967429   1 MRPDDINPRTGLVVALCSVFLVFGFMFTVSGVKGETLGDVPLIAIGPAICLPGVAAIILAKKTNGCTRCPGR-------- 72
gi 512813846   1 MRPDDINPRTGLVVALVSIFLFFGFMFTVSGFKGESLGPIPLIAIGPAIFLPGVAAISLARRTDGCTKWPYK------KW 74
gi 149412983   1 MRPDDINPRTGLVVALVSVFLVFGFMFTVSGMKGETLGNIPLLAIGPAICLPGIAAIALARKTEGCTKWPENellwcrKL 80
gi 823473948 226 LRPDDINPRTGLVVALVSVFLVFGFMFTVSGIKGETLGDIPLLAIGPAICLPGIAAIALTRKTDGCTKCPEN------MR 299
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74748275   81 PCFRKPKDKEVVELLRTPSDLESGKGSSDELAKKAGLRGKPppqsQGEVSVASSINsptpteEGECQSLVQNGHQEETSR 160
gi 557018456  75 DCCKTNKEKEDADLLDTPWDLESGKGSCDELDKEGDPKGPR----KGDDSVSSTTT------TGESRSLIRRVDQDEVMR 144
gi 972967429  73 --CRRKRQKETSQLLRSPWHLGSGKGSCGELGRLHKDRAPR----SGEDSVSSTTT------VGEARSLIRQVDQDEVMR 140
gi 512813846  75 ICCRKTKDKEDIELMKTPPDMESGKGSSNELDKKGEKKEKD----EECES-SKVIT------IEDASILIKGVDQHEVLK 143
gi 149412983  81 PCFKKAKDKEVIELLRTPSDLESGKGSSDELMKKTFLRGKLs--pKGVVSVSGSATattatgAGECKSLNQKVEQDEMLR 158
gi 823473948 300 PCCKEVKDRDGMELLRTPSDLESGKGSCDELARKAYRKDRRg--lRGEDTVFICTTsttaaaTAECKSLTKKVEQEEMLK 377
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74748275  161 YLDGYC---PS------GSSLTYSALDVKCS--ARDRSECPEPEDSIFFVPQD-SIIVCSYKQNSPYDRYCCYINQIQGR 228
gi 557018456 145 YLEACY---PSsvfsgvRDVSYYCVIDRMCS--TRDSVAYSSAKDNTVCTPRD-SVVVYSHRDSGPYGRYCCYINPGELN 218
gi 972967429 141 YLQACY---PStvfmgvRDVSSYCVFDHKRA--LRESAAYSTAHSSVMYLPRD-SIVVYSRRDSSPYGAYCCYINPGDFR 214
gi 512813846 144 YLDQCY---SSntl-pgGVESSCSVFDKTCA--T-DRIIYMATEEKVTLDPRDkEAAAFSHKQ----DRYCCYVQATEVT 212
gi 149412983 159 YLEGSQ---PSgacpaaGSTPTFSALDPKCS--TWDRSDCPEPEDHIFFVPQD-SIIVCSYKENSPYDRYCCYINPSRVG 232
gi 823473948 378 YLDCCYpemPEnv--lvGDVSTYSALEKKSSspSRDSTPCPDIEDNIFVAPKD-SIIVCSYKDNSPYDRYCCYINPTGVN 454

                 ....*..
gi 74748275  229 WDHETIV 235
gi 557018456 219 WDQETIV 225
gi 972967429 215 WGQETVV 221
gi 512813846 213 WDQETIV 219
gi 149412983 233 WDHETIV 239
gi 823473948 455 SDQETIV 461
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