Conserved Protein Domain Family
CiPC

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pfam15800: CiPC 
Clock interacting protein circadian
CiPC is a family of proteins found in eukaryotes. The protein was identified in sheep as a gene-orthologue involved in regulation of the circadian clock. Proteins in this family are typically between 220 and 400 amino acids in length.
Statistics
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PSSM-Id: 318094
View PSSM: pfam15800
Aligned: 16 rows
Threshold Bit Score: 295.125
Threshold Setting Gi: 597775937
Created: 29-Jul-2016
Updated: 4-Aug-2016
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 123888583  57 SEKDsgySDTGSDSL----QTDADDRQSSASEPQNHKGsLH---GSHILVSGTPELTPIFIIKDVVLKQPGQSGqdhilP 129
1_pfamImport   1 TDKD---SDASSGYFsaldQTDIEDIGPTGSAALNMPT-AP---RVPFITGSHPGISPMIVMNNFVLKQPNSTA-----P 68
2_pfamImport   1 SDKDsgySDGSSECLsameHTDSEDVLNTLCWNAEDGP-WP---CPVTTSGSFPALSPMVVMKNVLVKQGSSS------- 69
3_pfamImport   1 SDKDsgfSDGSSECLssaeQMDTEDMLNPLGWTGDDGS-RQ---KPDVGSSSFPALSPMVVMKNVLVKQGSSS------S 70
4_pfamImport   1 SDKDsgfSDGSSECLssaeQMDSEDMLNTLSWHGEDGP-RQ---NSTIASNSFPALSPMVVMKNVLVKQGRNS------S 70
5_pfamImport   1 SDKDsgfSDGSSECLssaeQMESEDMLSALGWSREDRP-RQ---NSKTAKNAFPTLSPMVVMKNVLVKQGSSS------S 70
gi 573889350  37 SERDsgfSDASSEYLsaveQTDAEDGQKTSAQSIKSKSqLP---QLAVMGGGYPGLSPMIIMNNVLLKQASNCP-----P 108
gi 556946940  38 SDKDsgfSDGSSEYLsaaeQTSSEDMPNFPSWILASRA-QQ---NTMLVNSPFSALSPMFFMKNVLVKQPICD------Q 107
gi 597741126  12 lERDsgfSDASSGYLssvdQTDFEDVRSNTSTVQPMLS-GS---QPPLRPGSYPDVPSMFKMNNIVLKQSCSVN-----P 82
gi 432944527  29 SERDsgfSDASSEQTssmdTTDSEDSPHPAVRQGHRSA-GSvssGLAVVGGSYSSLSPMIIMNNVLLKQPADNP-----P 102
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 123888583 130 SSLSWGGGTAGGQAP-THVLLL---QQPGInqSTPLHILKshpqrsESKNAKKSKNTYLPILNSYPRIAPHPSKKA---- 201
1_pfamImport  69 ALKPWSLNTSLDVVP-QSQLLY---LQPVAkcLPSGDSTS------QSFDKQKHSKKHAPLQSTFQKIAPHPAQEPt--- 135
2_pfamImport  70 QLQSWTVQPSFEVIPaQPQLVF---LHPSI--PPPINPHP-------VGKKRNDSTNYLPILNSYPKIAPQPCKR----- 132
3_pfamImport  71 ELQSWTVQPSFEVISaQPQLVF---LHPSV--PPPVSPFH-------AGEKKSDSRNYLPILNSYTKIAPHPVKR----- 133
4_pfamImport  71 HLQSWTVQPSFEVIStQPQLVF---LHPSV--PPPVSPYP-------AGEKKNDSRNYLPILNSYTKIAPHPGKR----- 133
5_pfamImport  71 QLQSWTVQPSFEVISaQPQLLF---LHPPV--PSPVSPCH-------TGEKKSDSRNYLPILNSYTKIAPHPGKR----- 133
gi 573889350 109 AVKPWGFQPAIEVIP-QPQVVF---LQPVI--SNGITNTQk-----GPQDKRRRSQKYLPILKSYPKIAPHPGESSs--- 174
gi 556946940 108 LVQSWAVQPSIEVIPaQPQLLL---VQPAV--PQTINSRS-------TRDNKADSGSYLPILKSYAKIAPHPGKKLtpgk 175
gi 597741126  83 ALKSWSFNPSLEVVP-QSPVVL---LQPMV---PSSSCTPl-----TPANQQRQSKNYLPILNSFLKIAPHPIQGAe--- 147
gi 432944527 103 AMKPWGVNPTVKVVQpVVQQPPfvfIQPVV--SGQTSSASk-----ECTSRRKRSKKYLPILKSYPKIAPYPRDSSg--- 172
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 123888583 202 -TEKPTTNRGSNTe----eHSLS-KRVCTEEKREKVST-----------T------------------TQASK-QHPHkQ 245
1_pfamImport 136 vDQGPGAINRRSS------HSHA-GRHHRHRYEDKPFH-----------NfplkqdvsetfsgygvdpSISSLeEIGH-T 196
2_pfamImport 133 -DHSFDLEERQET-------SCH-KRLCTEASKMENSP-----------V------------------SRST-------- 166
3_pfamImport 134 -SLSLTLEERGEA-------SDR-KRTCTDRHRTSLSS-----------L------------------GPTKTd------ 169
4_pfamImport 134 -GLALNPEERGET-------SMQ-KRVCTERHRTSLSS-----------T------------------GPTKTs------ 169
5_pfamImport 134 -GLSLGPEEKGTS-------GVQ-KKICTERLGPSLSS-----------N------------------EPTKAg------ 169
gi 573889350 175 eRSASGSSERSGS------ASARvDRASALRHRRHSRE-----------K------------------QLSRLsSTASpT 219
gi 556946940 176 dAISPRDGRRGLSd----sHKKQ-KRVETS----------------------------------------RTSsAFRSsS 210
gi 597741126 148 gDLGTNSNHMSSSg----qRQAA-KRCHNDHHETQTRSlslkqdtsettT------------------VASHSdDSCVfS 204
gi 432944527 173 sSGRGAASSSSGSgrssssLNSN-QWEAGQREK----------------T------------------LCGSIsDSt--T 215
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 123888583 246 PENNLLSNSHSLsrslsagh------etstdthkNRSPCRPSSPSASLSVSSPSVSSTqipsppssVDLIQTRKEPHKHC 319
1_pfamImport 197 VEDMHVKDSPSR----------------------LSDFQEPHTTTSPFSLCTDSFLAA--------FPQKFPKTSISQSS 246
2_pfamImport 167 ----VLSTSPFAhipvsfkapqdsnqqsssslmtTGKVS---------TLPGFHCV-SadtpkvpgLASLLPFGALQTAK 232
3_pfamImport 170 ----VSPSSPSAvppdlrlaqds-arqssssslaGGALR---------TVHSIQLGPSgrlvkgprLTPEVPPSPPFTVD 235
4_pfamImport 170 ----ILPSDPSTpvppstklaqdsvrqslsslvaSRSLR---------TVPDSQEVLSstmakapnLTFASPASPLGSSD 236
5_pfamImport 170 ----AVPSSPSTpappsaklaedsalqgvpslvaGGSPQ---------TL---QPVSSshvakapsLTFASPASPVCASD 233
gi 573889350 220 PSGLPLPLTPEPstrkhhsslsktesassggqptPPASSQEAPPpar----------------spgLAPVPPAAASPSRT 283
gi 556946940 211 AAQPFSPQSSGTnkqqnseilpsnrtqtnselacNGHTGRQEEDCFTPTLESGHLQLSanaasdeaLFLCPSPSVGQIAS 290
gi 597741126 205 PNFENMASPPTL----------------------PALEEDDDGTTTPFSVCSDSYLSP--------FSEASPIDTYASSD 254
gi 432944527 216 PGR---PATPGTtsplhqsrps----fqttetsssPRREKPSSAVISTDV-----LTPttgskdpaLSRLRPSSGENNDS 283
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 123888583 320 PGQKSDSGKGSHTFkg------------------------taRH---RRFLNTVEILSQSGLLDITLRTQDLLRQNAATD 372
1_pfamImport 247 DVESIPEALSPSSS----------------------------KR---KRFCNTYNILNRSGLLGITMRTKELIRQNKRSQ 295
2_pfamImport 233 CTPHENESAAQTTMqsavwslplipee--tcttpelllqqqsKC---RRFQNTLVVLRRSGLLEITLKTKELIHQNQVTQ 307
3_pfamImport 236 GSGRGAENTVSPSTpaapssppatvgql-rrtleafpeprqsKH---RRFQNTLVVLHRSGLLEITLKTKELIRQNQATQ 311
4_pfamImport 237 STLHGLESPMPLSMlsapysppgagdql-chspetfleqrqsKH---RRFRNTLVILHRSGLLEITLKTKELIRQNQATQ 312
5_pfamImport 234 STLHGLESNSPLSPlsanyssplwaaehlcrspdifseqrqsKH---RRFQNTLVVLHKSGLLEITLKTKELIRQNQATQ 310
gi 573889350 284 DPDPDPEEKGSVLE----------------------------KRnkrKRFCNTYNILHKSGLLGITLRTKELIRQNRKTQ 335
gi 556946940 291 AQELGPAAATSGQMaqq-----------------------qsKQ---KRFQNTFDVLHKSGLLGITLKTKELARQNQSTQ 344
gi 597741126 255 DAENVPGSLSPSSS----------------------------KR---KRFCNTYNILNRSGLLGITMRTQELISQNKRSQ 303
gi 432944527 284 DQCSL--SDCDSDA----------------------------KR---KRFCNTYNILSKSGLLDITLRTKELLRQNRHTQ 330
                        410       420       430
                 ....*....|....*....|....*....|.
gi 123888583 373 RDIAQLRQHAQLLFQAAQAGVdaPAAWEKLQ 403
1_pfamImport 296 AQLQSLQAQTDLFLEAICSRD--PKVWTRLQ 324
2_pfamImport 308 AELDRLKHQTQLFIEAIKNNA--PQSWAELE 336
3_pfamImport 312 VELDRLKEQTQLLVEAAQSNA--PQAWAKLQ 340
4_pfamImport 313 IELDRLKEQTQLLMEATKGNA--PQAWAKLQ 341
5_pfamImport 311 VELDQLKEQTQLFIEATKSRA--PQAWAKLQ 339
gi 573889350 336 SELDRLKAHADLFVEAIRSGD--PQVWTKLQ 364
gi 556946940 345 NELDQLKEQTRLFVEVLQSNN--PLVLAQLl 373
gi 597741126 304 AQLQKLQAQTDLFLEAISSRD--PQVWAKLQ 332
gi 432944527 331 SDLDRLREQTDLFLRALQSGD--ASLRLQLQ 359
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