Conserved Protein Domain Family
Itfg2

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pfam15907: Itfg2 
Integrin-alpha FG-GAP repeat-containing protein 2
Members of this family are annotated as being integrin-alpha FG-GAP repeat-containing protein 2.
Statistics
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PSSM-Id: 318179
View PSSM: pfam15907
Aligned: 14 rows
Threshold Bit Score: 414.09
Threshold Setting Gi: 552926835
Created: 29-Jul-2016
Updated: 4-Aug-2016
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780109564   49 KGDNTVPFATASNLGMIVCTEIADVCNANKNVAVVLCADGLCYLYAIdkqsfadrqpqegkqaesapnTSDGQGAEEtpQ 128
gi 1043405294  49 KNEQSKPWLTRSCSGMLTCVGVGDVCNKGKNFVIAVSAEGWFHLFDL---------------------SAKP----EgpL 103
gi 260827074   49 KGADTTPWRMASGLGMTSCAAVGDVCNTGKNVIMTLSAEGWCHVFSV---------------------SPNEKQEAAvaQ 107
gi 321466832   49 KGSASKCWRRASDLGMVTAIGVGDIFNAGRNSLVVVNGEGWCYIFDF---------------------L--TDTCSD--- 102
gi 762141982   50 KGSSKSPWKRCSSLGMITCIGVGDVFNKGKNVLVALTAEGWCNIFDI-----------------------KADSSSEtsK 106
gi 156365496   49 KGTASKPWRVSKQNGMITCVGSGDLWNRGKKVLVAITADGWCHLFDV-----------------------KTSAQKSieR 105
gi 241608418   49 KYRQSRPWATASDLGAVASIVVGEITNDSQNKIVSISCDGWCNIFAL-----------------------QSDATE---- 101
gi 198436002   49 KGDSTKPCWESSDFGDITCLTIADLCNEGKNCVAVFTTDGAFSILDF---------------------NKSLDAP----- 102
gi 565303100   49 KNDESQPWTLRSCQGMLTCVGVGDVCNKKKNLVVAVSAEGWFHLFDLtp------------------pLKHGDVLGH--H 108
gi 449484868   49 KNDDSKPWAVRSCQGMLTCVRVGDVCNKGKNFVVAVSAEGWFHLFDLts-----------------lnSKHPDASGH--H 109
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780109564  129 ETRKPLALTPFHTQHLPANSKVVLVADIDNDGQLELVIGYTDRVVQAYRW------QDktllPEEAEGSGEKGFVLLQRW 202
gi 1043405294 104 DPLQGDEQKATYTQHLPANTKLALISDIDGDGLCELVLGYTDRVVRAFRW------ES----PPDA-DLTCGQLVTLKKW 172
gi 260827074  108 AKGGPEEMTPVYQQLLAANGQAIVIADIDKDGKNEIVIGYTDRVVRAYSWve---sTS----ATTGQDVLSGKFVLLQTW 180
gi 321466832  103 ---GELPMKPTHVQRIPANTKVLLLHDVNSDGMIELVIGLTDRVVRTYQW-------------------INTKLVGLNKW 160
gi 762141982  107 DLEAGDHLAPTFNQHLPANGKVLLIEDVDGDGKVELTVAYSDRVVRCFRWs-----TV----QDPETEEVTNNLIQIQKW 177
gi 156365496  106 KPEDGYTMRPSYSQLLPSNAKTLLIADIDGDGLCEMVTGHTDREVYVHRWiaeqltTE----SSPAKEIPRGHFAQIKSW 181
gi 241608418  102 --EERKHMAPLHSQRLPANTKMALLADINGDGKVELILGLTDRVVRTYQW------T------------CFLELVGLQKW 161
gi 198436002  103 ---------IIHSDHVIPNIMNVLVSDLDSDQLNELIACHSDHCVSAYRW-----------------NSKHKRFTILQRW 156
gi 565303100  109 ELLNPDDPKLAFKQHIPANTKVMLIDDIDGDGRNELVIGYTDRVVRAFRW------ED----SPEGSDSLSGQL------ 172
gi 449484868  110 ELAGAEEQKPVFKQHIPANTKVMLINDIDGDGKCELVVGYTDRVVRAFRW------ED----SSENPDHVSGQLILLKKW 179
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780109564  203 NVDGQVGSLSLSKDTD-GSPMLVVSQPGCNYAELKCSWVMQQGAedDNPEDQSC----SAISKDPYVSMHLiTFLRARHA 277
gi 1043405294 173 LLEGQVDSLSVNPAAD-GTPELMVSQPGCGYAVLLCTWKEDPSLgtE-GAGAAE----TREVSTRDVILHQ-TSLRIHNK 245
gi 260827074  181 ELVGQVGSIVVTTGVD-GQTELLASQPGCTYTTLLMKDTGKGEGgdKEKDEEEEeeeeRQQASGETVIFHPlVSSRARNP 259
gi 321466832  161 EFANQIGTVGINDMAN-RTPSLLVAHPGGTFIRLKCKPLENC----EDHGKEEP----RELLSKMSIDYHPlAYSHMRNP 231
gi 762141982  178 QLAGQIGSLTVNFTEE-GHPELLVAQPGGEYVTMTFKQGSELDLs-SDSEGYNE----EVLKSD-----------QRANQ 240
gi 156365496  182 SLYSQITSLVIYKAS--RTQYLLVSQPGGTFINLLATDISKt----EDKQEEHS----DGFKADFPLPFLRs----KQNQ 247
gi 241608418  162 EFANQVGSFPRAPSPS-SRMSTTSSRPSPVLKFLFQS-----TAffPRHVGRNP----HGLTKSNQNTHHKlDSSHMRNP 231
gi 198436002  157 TLRQLVGNISIHVSSDeGVPSIIVSQPGCSYAVLSINWNQSEAVktGPNISEST----VTYTP-------LsSQSRSQNP 225
gi 565303100  173 -----VDSLSVNSGAD-GSPQMMVSQPGCGYAVLLCNWKQEQQPptETGDGSAS----SREGPVRDVVHHQ-TSGRIHNK 241
gi 449484868  180 LLEGQVDSLSVNPGPD-GSPELMVSQPGCGYAILLCTWDTEQRDtaAGRDGSAP----SSEAPVRDVILHQ-TSGRIHNK 253
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780109564  278 DVSTEIVAGLS---KGEKEGGEDFepepD-RIAMCTLDGTLMLI--------EKDKSLWSRLVDHQLFALTKLDIMCDGW 345
gi 1043405294 246 NVSTHLIGSIK---RGPSAGRKEA----G-LFALCTLDGTLKLMqgsdrllqGSDQLLWSVQVDHQLFALEKLDITGNGE 317
gi 260827074  260 DVSTEIIGNLAtddAGDCPGR-------G-LYAMCTLDGTLMLG--------QGEEIVWSLQVDHHLFSLTKLDVTMDGK 323
gi 321466832  232 NVSTEILGNIS---QGISHQDENQ----GaLYAVATLDGTLMMV--------RDEQILWSLQVDHQLFALSKLDITGDGR 296
gi 762141982  241 SASTEIIGGIS---RQTSKQPGT-------YYAICTLDGNLLLV--------EKKQILWSLQVDHQLFSLKKLDVTGNGK 302
gi 156365496  248 GITTTMVTLSP---NHSSNRDNDDp---E-LLAIGLLDGDLSVL--------NQNRILWTLHLEQNIFSLSKLDVTSDGY 312
gi 241608418  232 NVSSAILGGV----RGTRDGRLTD----S-LMALATLDGTLMLV--------DGDNILWSLQVDHQLSALTKLDIVGDGR 294
gi 198436002  226 TITCQILGDIT---KSSSSPA-------G-YFALCTLDGTLKLM--------EEDKILWSLQVDHQLFALYKLDILGDNR 286
gi 565303100  242 NVSTHLIGTIG---RGSSKEHKGL----G-LFALCTLDGTLKLMe-------GADKLLWSVQVDHQLFALEKLDVTGNGY 306
gi 449484868  254 NVSTHLIGSIA---RGSSENNGS-----G-LFALCTLDGTLKLMe-------GADKLLWSVQVDHQLFALEKLDVTGNGH 317
                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 780109564  346 DEVVACAWDGQTYIIDHTQQSIRFHLKENVCAFTAGLYSt--NGKNTPCLVYATFNNKIYIYWNVQL 410
gi 1043405294 318 EEVVACAWDGQTYIIDHNHAILRFQVEENVSAFCAGLYAc-rEDENSPCLVYVGFNQKIYIYWAVTL 383
gi 260827074  324 DEIVACGWDGQTYIMDHLRNMVRFQFDQPVNAFCAGLYAv-tPGKNVPCLVYATFHNNITLHFNTTL 389
gi 321466832  297 EEVVACSWDGQTYIVNQEKQTVRFQFDQSVSAFTAGYYSlnsQSSSLPAFAYATFHNKIYVYYNVSL 363
gi 762141982  303 EEVVCCSWDGQTYIVNHNRAVVRYQFQESVAAFTAGLYGv----dNNPSFVYATYNNKIYIYNSIQL 365
gi 156365496  313 EEIIACAWDGSTYIIDSDQNIVKFEFRENVLAFGAGHFAv--NGANVPCLVYVTFSNTVVIYWNITL 377
gi 241608418  295 DEVIACAWDGQTYIVDEDRQSVRFQFDEAVCTFTAGQLTl-sPGMTLPCLVYATFGHRIVAYYNVTF 360
gi 198436002  287 EEVIVCAWDGQTYIVDHDRNVVRYQFLDNVQAFCAGSFSi-dSKQNRPCFVYSDFHNHVWLYYDVKL 352
gi 565303100  307 EEVIACAWDGQTYIIDHNRTVARFQVDENVSAFCAGFYSc-kGDYNSPCLVYVSFNQKIYIYWDIQL 372
gi 449484868  318 EEVIACAWDGQTYIIDHNRTVARFQADENVSAFCAGLYAc-kEGSNSPCLVYVSFSQKIYIYWDVQL 383
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