Conserved Protein Domain Family
FXR_C1

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pfam16096: FXR_C1 
Fragile X-related 1 protein C-terminal region 2
FXR_C1 is a small highly conserved region of the C-terminus of Fragile X-related proteins 1 and 2, FRX1, FRX2. The family is found in association with pfam05641, pfam00013. This family is immediately C-terminal to the core C terminal region, PF12235, and contains at least one block of RGG repeats that bind to G-quartet sequences in a wide variety of mRNAs.
Statistics
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PSSM-Id: 318344
View PSSM: pfam16096
Aligned: 8 rows
Threshold Bit Score: 87.6307
Threshold Setting Gi: 348560995
Created: 29-Jul-2016
Updated: 4-Aug-2016
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 972956124 286 SSTIS-SVLRDPDSNPFSLLD--RAgELDQAGDTDASESQASGDRRRRSRRRRTDQEPSVMDGAAESDGPSVSENGLE 360
gi 817256519 484 KSSIS-SVLKDPDSNPYSLLD--NT-ESDQTADTDASESHHSTNRRRRSRRRRTDEDAVLMDGMTESDTASVNENGLG 557
gi 765117971 500 YSNNS-GSWDRDNTYSHGALE--TNtETDHTADTDASESLLPANRRRRSRRRRTDEDATMMDGMSESDNASVGENGIV 574
gi 348560995 502 nsssissVLKDPDSNPYSLLD--TS-EPEPPVDAEPGEPPPASARRRRSRRRRTDEDRTIMDGGLESDGPSLTENGLE 576
gi 734614678 516 YHNSSaGPRDHEDNHAYGASEvnT--ETDQTADTDASESNVPANRRRRSRRRRTDEDATLMDGMSESDNASMSENGId 591
gi 939318629 498 YSNSS-GPRDHEDNHHYGALE--VNtETDQTADTDASDSNLPANRRRRSRRRRTDEDTTLIDGMSESDNASMSENGTv 572
gi 33585602  486 SNSIS-SVLKDPDGNPYSLLD--NT-ETDQTADTDGSESQMNTSRRRRSRRRRTDEDTTVMDGMSESDNASLSENGLV 559
gi 637372583 493 SSSIS-SVLKDPDSNPYSLLD--NT-ETDQTADTDASESQPVSNRRRRSRRRRTDEDATMMDGALDSDSVSVSENGVE 566
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