Conserved Protein Domain Family
TIC20

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pfam16166: TIC20 
Chloroplast import apparatus Tic20-like
Chloroplast function requires the import of nuclear encoded proteins from the cytoplasm across the chloroplast double membrane. This is accomplished by two protein complexes, the Toc complex located at the outer membrane and the Tic complex located at the inner membrane. The Toc complex recognizes specific proteins by a cleavable N-terminal sequence and is primarily responsible for translocation through the outer membrane, while the Tic complex translocates the protein through the inner membrane. This entry represents Tic20, a core member of the Tic complex. This protein is deeply embedded in the inner envelope membrane and is thought to function as a protein- conducting component of the Tic complex.
Statistics
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PSSM-Id: 318410
View PSSM: pfam16166
Aligned: 14 rows
Threshold Bit Score: 148.708
Threshold Setting Gi: 460409345
Created: 29-Jul-2016
Updated: 4-Aug-2016
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75267833   97 RRPIEPAR-VAKDDFFKIKLPKIAERPEWWWRTLACVPYLISL----QISDVGFYVQPFLEKHDAigdMIYFIPGAINRW 171
gi 75151589   95 RKTLLTPR-ASKDVPSSFRFPPMTKKPQWWWRTLACLPYLMPLhetwMYAETAYHLHPFLEDFEF---LTYPFLGAIGRL 170
gi 75125425   79 prTQVGCRa----SLSSFSFPELETKPRWWWRTLACVPYLLPLhnmwSFADAVYQLHPYLQQFG----LFYAFIDTMALV 150
gi 75171614   43 RAATLVLQsKGDDSVDASD------------RIISAVCYFYPFfdgiQYGKF------IITQYQPfqiLIQPLFPAIRAF 104
gi 75100577   41 RRATALTTrASYTPTPATE------------RVISIASYALPFfnslQYGRF------LFAQYPRlglLFEPIFPILNLY 102
gi 460413103  31 KRPTIRAQsKNDDSVDGPD------------RLISAITYFYPFfdgvQYGKY------VITQFAPiqtLIQPLVPAIRVF 92
gi 566167549  37 PRRLILAKsNGNDSVDTTD------------RIISAVCYFYPFfdgiQYGKY------VITQFSPiqaLIQPLFPAIKVF 98
gi 573951143  93 RRPEVGCRaSS--SLASFSYPELTSKPRWWWRTLACVPYLLPLhnmwSYADVIYQLHTYLQGFS----LVYTFIDTMTLF 166
gi 168019532  27 RRCNVTPRaATEDVPSFKGFAPMQEKPKFWWRILACVPYLMPLsetwMYAETAYSLHSFIEDYEF---CTYPFLILIGSL 103
gi 571500885  85 RFNSKICGqAFKYHASGFRIPANAEKPEWWWRTLSCIPYLIAL----QMSSTGYYLDPFIQKFPFfqnLIFYIPGGVNRL 160
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75267833  172 PT--WFFMVYCYLGYMWVVKNKELPHYLRFHMMMGMLLETALQV-IWCTSNFFPLI--HF-KGRFGMYYWMAIGFTYICL 245
gi 75151589  171 PS--WFLMAYFFVAYLGIVRRKEWPHFFRFHVVMGMLLEIALQV-IGTVSKWMPLG--VY-WGKFGMHFWTAVAFAYLFT 244
gi 75125425  151 PG--WLFLMIFMTVYFFVVRRKWLPHFLRYHVILAILLDTGSQA-LATMCNWNPSI--VY-QGKPMVFFWMTIAFIQIST 224
gi 75171614  105 KSfpFNGFLIFITLYFVVVRNPNFSRYVRFNTMQAIVLDVLLIFpDLLERSFNPRD--GF-GLDVVMSLDSTVFLFLLVS 181
gi 75100577  103 RSvpYASFVAFFGLYLGVVRNTSFSRYVRFNAMQAVTLDVLLAVpVLLTRILDPGQggGF-GMKAMMWGHTGVFVFSFMC 181
gi 460413103  93 KSfpLNGLLVFFTLYFIVVRNPNFSRYVRFNTMQAIVLDVLLIFpDLLERSFNPSD--GF-GLDLMMSFDSTVFLFLLVS 169
gi 566167549  99 KSfpLNGFLVFLTLYFVVVRNSNFSRYVRFNTMQAIVLDVLLIFpDLLERSFNPRD--GL-GLDLLMSLDSTVFLYLLVC 175
gi 573951143 167 PG--WLLLVIFMTVYFFVVRRKWSPHFLRFHVILAILLDTGSQA-VATMCTWMPSI--VY-QGKPMQYFWMAIAFIQIFT 240
gi 168019532 104 PS--WFLLAYFFGAYLGIVRNNRWPHFLRFHVVTGMLLEIIVQV-IGTVNDWVPQA--VY-WGKFGAHYWLAVTFAFLFI 177
gi 571500885 161 PI--WFPMLYCYVAIVWVVKNKDLPLIFRFHVMMGMLLELALQI-VYTSSNFMPLI--HFpGGTLGMYYWTGVALAYIFT 235
                        170       180
                 ....*....|....*....|...
gi 75267833  246 LLECIRCALAGVYAQIPFMTDAA 268
gi 75151589  245 VLESIRCALAGMYADIPFVCDAA 267
gi 75125425  225 VLECMRCALAGMYPSVPFVSQTA 247
gi 75171614  182 LIYGFSACLFGLTPRLPLVAEAA 204
gi 75100577  182 FVYGVVSSLLGKTPYIPFVADAA 204
gi 460413103 170 LVYGTSSCLLGQLPRLPIVAEAA 192
gi 566167549 176 LIYGSTSCLFGQIPRLPIVAEAA 198
gi 573951143 241 VLECMRCALAGMYPNVPFISHTA 263
gi 168019532 178 VLDCIRCALNGMYADVPFLSD-A 199
gi 571500885 236 MIMCIRSALLGRFVRIPLVSESA 258
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