Conserved Protein Domain Family
DUF5054

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pfam16477: DUF5054 
Domain of unknown function (DUF5054)
This family consists of Glycosyl hydrolase family 38 proteins around 700 residues in length and is mainly found in various Clostridium and Rhizobium species. The function of this family is unknown.
Statistics
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PSSM-Id: 318639
View PSSM: pfam16477
Aligned: 13 rows
Threshold Bit Score: 282.752
Threshold Setting Gi: 761903372
Created: 29-Jul-2016
Updated: 4-Aug-2016
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503018846 266 AASDPLKVARYRALARSIPQIRETG-----DPGERTFTRTLLLVPEHTWGMDQKRFLPDFLSWSKPAFQAARKRDlipqd 340
gi 524088119 280 AAADPYKAAALRELTALKNEWLQSGemvrsSKEYIGFTDNLMCVAEHTCGMDMKTYLGDYENYLKKDFEKARKKGv---s 356
gi 504051499 266 SATDPVKSACYRALQRVYDRFAEDk----iTPSRLSFGRKLSMVAEHTCGVDIKTYLRDEQAWNRDDFEAAREND----- 336
gi 524192921 258 IGSDPWKVSRYRELIRLKDQWQREGrfsrdCEGYDAFMMNLMLIAEHTWGLDYKKYLADFKNWTKEDFQKARAADettle 337
gi 503038831 272 IASDPVKVRGLRRLLGLKDQWKKQGsfdpdLPEFHGFLENLLMVCEHTWGLDYKKHLFDFKNWKKEDFKKARKENrvtea 351
gi 511346784 260 VASDPYKVAAYRELLGFRDQWTASQpsapnTPQWQDLCRNLMLVCEHTWGKDSKRWFADYRNWEKHDFLEARKRDlvted 339
gi 524162691 265 AATDPLKVSAYRRLLALKEQWLQKGqitreDPAYQNLMENLLLIAEHTWGMDVKKYLLDFKNWNKKDFHQARTLDttsae 344
gi 505429559 266 IATDPYKVSVFLELLRLKHKWIKEGklekdSKIYRNFMGNLLMIPEHTWGLDFKKYMADYKNWRKQDFLKARNLDklsds 345
gi 506215176 267 IASDPWKIARYRELLRLRDRWIEDGrldrdSEAYARFCNRLMLIPEHTWGLNNSVYLVDFVNYSSADLAAARARD----- 341
gi 503334029 294 IASDPPKLAEYRALARLRQQWIQDGrftigDATDRRFLRRFLLAVEHTWGTDTKSYL-DNDHYRPTAIVAADQQG----- 367
gi 761903372 414 IASDPLKSSMYRSMALSLDQCLKDGacdlsDPVVSNATRFLIKLPEHTWGLPG---VENTEDWANSDFEKART------- 483
gi 514684221 319 IASDPYKNTAYRALERARVSCLGSGacsaaDAVMLNFTRLLLKNPEHTWGGDVKKYLHDEDNWLNVDFHRLQYS------ 392
gi 497198347 270 IGTDPGKTARYRELNRLRERWTANGrlkegSAIDLRLAESLLLTAEHTWGMDIKKHLADWTHYTAKKFARVRR------- 342
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503018846 341 TLQEGVLSYTKIPls-fyDEL-KG---RLSYRLFERSWKEQRGY-LEQAVAALQT--DRARDiASKALRETEPKWPDNRg 412
gi 524088119 357 AIRHPFRDYPQNMii-alGRI-AGcnkPANYRTIEKSWEEQREY-IKNAVCCLKG--TRKKQ-AENALKKLIPETPETCa 430
gi 504051499 337 ----------------------------PRFQYAEASWQEQRAY-CDDAVAALEA--NDQAV-AKAALSEICCPLPHVGp 384
gi 524192921 338 FLTNRNAQMREVLdi-dfKRY-RGgvfTGSYRYYESSHEEQREY-LKKALEELPA--DLKAE-AERALTGCIPVKGESEg 411
gi 503038831 352 MFTERNASLLHAI-----CREkGAehlESSYERYESSFQEQRAY-LQEAVRLLPE--DLREE-GEQALTWDHLSKEEIWe 422
gi 511346784 340 ALLPVGKTLREFIls-qnMIQ-NG---RCSYSTLESSWEEQRDY-VKAALEELPE--PLRAE-AKEKLLSLRPDQApq-- 408
gi 524162691 345 SYGCWNQSILAGMke-elLHY-HGdpiTSSYTAFEASHQEQRDY-LTKGMSELPP--SLLKE-AQTAMVFSYPVIPKTAv 418
gi 505429559 346 YIPEKYDQYARFArnefkAQIkHMgwkDRSYSFFESSHREQRYY-LDNAIKVLSK--DLKED-AQKAIKELT-EYPEINh 420
gi 506215176 342 IVEDNTRKKFDYL-----CQQaNG---TRSYSHYESSWQEQRDY-LEEALQSLPA--ALAAE-ARTELDRMSPQHTVLNs 409
gi 503334029 368 ---------------------------LAGYARMETSWKEKRDD-LTEAISTLPS--VLQAQ-VTASLQKLDPIEPSSDg 416
gi 761903372 484 ---------------------------TAEFIANRESWFEQRTF-INLTLEASEG--HKLNEyLTSGLSELKLTDPPNLs 533
gi 514684221 393 ---------------------------ADNYVQIASMWQEQRDWgLKFARQAVPTshPLTSF-ISDELAGTSPQLPSLSg 444
gi 497198347 343 ---------------------------LSNFRKLETSWCEQRRY-TKTAVAALPD--SLRRE-ARAALARLRPAPFRSGs 391
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503018846 413 ------fTHSEEKrsFSSGKWQIEVDAaTGALlrCYHGGSRL---ELAsPGEPFCRYRYHVHDHREFSRFFSSYLLPDES 483
gi 524088119 431 k-----kFDIANV--LTAGKWRLKISG-TGSI--EKLTCGGD---EVI-RENTVCAAEYIGFNDDDYDFWLNHYSRDIEK 496
gi 504051499 385 -------FEIDSE--AEFGGWSIKIDRdSGAIk-HLKSPDGK---ELFgLDDNLISFAHETYNAADVKAHMDAYLTHEE- 450
gi 524192921 412 r-----rVCVGEI--LEIGGWKAAVDG-SGAI--RKLERGGR---DWA-KDGAIGRLGYETFNALNCVQNYYRYNRAFYE 477
gi 503038831 423 eg---etVHPFEM--ISIQDWTAAFDG-SGAV--VYLEKAGK---VWI-QSGCFGRFTYETYGALNMVSEFYEYNHAFKE 490
gi 511346784 409 ------cVAPTSErrFQINGYQLEIVP-DGSLq-IQQTPHGK---APS--NAWLGRLEYRVYSAKTVTENLERYNRDLEH 475
gi 524162691 419 hq---qpLAP-----IVLKDVTVTVGK-NGEItsIQKHSSGN---TYV---LCLGKVEYETFGGKEVDDCYFSYGRDLSE 483
gi 505429559 421 ky---kkINYNEE--CEINGYSIAVLE-DGSI-----KVHGH---SLS-RPVILGKATYQLFGASTFNKWKKEYMVNLDA 485
gi 506215176 410 epvqpqpIETNEL--YELGQFQVSFAA-DGSIn-RLMDRSGK---AWAgEHQRLGTYMYETFGQENYDRFFKEYMTNLDI 482
gi 503334029 417 m----hpVRIGEV--IECPNFLLTFDA-TGAItrLQNRGSQK---EWAsPAHPLAVFTYQTLSLQEFTDFIALYIHSTA- 485
gi 761903372 534 dy---neIDASKVftLFNGKVEIGFDNsTGPIthLIYSTSSNkqlVFAgTNQSLGQFTYITYNESDFFFMQSRYDYAFN- 609
gi 514684221 445 ys---qvADVTKE--MRVGGFVVSFNAtTGAIasLVHASSET---VLAsTANQIGTFEYKVHAASEYETFFDEYAQRIDG 516
gi 497198347 392 vw---rsVDPAEV--FRLGMLTLQLDPeTGAIrrLTAGDSRT---SLAgRRNMLGCFFRETYSKSDYERFYRSYIREEQD 463
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503018846 484 HH-EWSLPDYTKPGLSRVAD-LRSLQFLPIRAAIwyrEGEECFTLHVCTQMPEEAVe---TYGA--------PAEVALSY 550
gi 524088119 497 NA-HWAVSDFSRPLLKYVKGkYPSGRFPYRLNGAy--QTGADQVLADLQCDQSVCE----ELGA--------PRRIQILY 561
gi 504051499 451 ---EWAILDHIKPGLNKAAT-AVSKSHRPMFEGL---AIADDRAILSYVMSSDIP-------GA--------IHNIQLVL 508
gi 524192921 478 NG-CWSEGDFSKPGLEFVED-LENRYYEFSVRDL---RVCGEELLIDLAGDAEAAE----KYGC--------PRAAQIKY 540
gi 503038831 491 NM-TWSEADFSKPGLENVEG-LFNRNYSFGVRDM---RKSGATVRILLSGNPAAVT----EYGC--------PERAWIIY 553
gi 511346784 476 TR-FWAEGDFAKPALDQVKG-LTDRSFSYTVEQV---EQKGDLLRLWLKADPQAGE----VYGA--------PRQAVVTY 538
gi 524162691 484 NF-FWSEPDFGKPGLRLEKD-IRHGIFSPCPLSI---HALENTLYITLGFAPEACE----QYGC--------PREMTTVW 546
gi 505429559 486 NR-LWAIPDFFKPGIEEAGApQHNIHFYSKVENC---TIKEKELIIELRFNDSECE----EYGC--------PRKAIMKY 549
gi 506215176 483 HH-GWADNDFGKPGIEYVKPrPEHQRYTASLRTLhleRHADYDIVTAEMKLPEVLSn---QYGA--------PRQINVFY 550
gi 503334029 486 ---DWAYKDFGKPNIDHFG--AQTAEWHPRLRGLwtnKLPTARRILAELVIPQQPTi---AAGTvlleniapPRQLFLEL 557
gi 761903372 610 -------AGYDKPGSDVAD--PLSQTWSTKLIGLyqcKDNENYFLTHLTMLDSKAHd---YYGA--------PADVWIKV 669
gi 514684221 517 KIpSYFPKDFGKPGLYNNSI-IANTTIVHAPIKAafvKNDSQAASVVLQLQPPNIAhlraNFGP--------PDSVWIEY 587
gi 497198347 464 ----WSRKDFTKHGLPTAVR-AATHHVSLSRLEL---HRDGDQARATLVFSPLAR-----RDGV--------PPLVCLRL 522
                        330
                 ....*....|.
gi 503018846 551 QFshRKP-TCL 560
gi 524088119 562 TL--KEN-GLT 569
gi 504051499 509 N---GESdKLE 516
gi 524192921 541 VF---GP-QIT 547
gi 503038831 554 TF---GA-ELL 560
gi 511346784 539 SF---GD-TIK 545
gi 524162691 547 EF--GKE-NIH 554
gi 505429559 550 IF--DDK-EIY 557
gi 506215176 551 SFhaNEP-VIE 560
gi 503334029 558 LLpdAEP-TIQ 567
gi 761903372 670 NLstSDSsLLR 680
gi 514684221 588 SF---DSsRVN 595
gi 497198347 523 EAdsGESaALH 533
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