2D2S


Conserved Protein Domain Family
Exo84_C

?
pfam16528: Exo84_C 
Click on image for an interactive view with Cn3D
Exocyst component 84 C-terminal
Exo84_C is the C-terminal helical region of the exocyst component Exo84. This region resembles a cullin-repeat, a multi-helical bundle. The exocyst is a large complex that is required for tethering vesicles at the final stages of the exocytic pathway in all eukaryotes. Exocyst subunits are composed of mostly helical modules strung together into long rods.
Statistics
?
PSSM-Id: 318681
View PSSM: pfam16528
Aligned: 32 rows
Threshold Bit Score: 211.306
Threshold Setting Gi: 761905080
Created: 29-Jul-2016
Updated: 4-Aug-2016
Structure
?
Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2D2S_A         16 KFLDEGVEEIDIELARLRFESAVETLLdiesqLEDLSERIS-----DeeLMLLNLISLKIEQRREAISSKLSQSI-L-S- 87
gi 338818093  449 RWIDEYGDELTMAIAIRDWEESVKLVEk----GQALSKSIE-----SnsS-AHSLLVSRLEQLVPSLVSQISHDL-S-S- 515
gi 74632700   444 REIDDLVNDLDVKIAHRRFAEATDIILe---nIKDDKES-T-----D---ITQQVLDIKLHQRQDELVAHLIDDV-A-T- 508
gi 296415590  436 RWVEAQMDELDEKIAHRQFEEAVVGVEk----LRGLGRALT-----SnnALVAELINFKVDERASRLATIITADL-T-E- 503
gi 575479720  415 RWLLELPDELDVLVAHRDFDNSVANLEkgklvLNFINTTRKilsgvDikTPRVQMLRASVENRIEILAKLVTSDL-A-Sp 492
gi 1022841402 490 SWIGDFSDELAVDISTREFEDAVVLIEkgksiLPKISGDAH-----AsqLFRSKLDS-RTSELVSALLNDLSDHS-I-R- 560
gi 330935411  452 RWVESQLDDLDIEIALQHFEEAVVKVd----rLRLLAKNIR-----SneM-AKAIVTYKVNERAAKLANVLVKHM-V-Eh 519
gi 573983123  450 RWVESQMDELDINIAMQRFEPAVAGVe----kLKSLSRGLK-----Sn-AVAQDFISFKVDERCSRLGDIVIRELdA-T- 517
gi 576040046  457 RWVESQMDELDINIALQQIEPAVARIEk----LRNLAQGLK-----Hn-VIAQDFISFKVDERRMKLAALLIREL-VtT- 524
gi 171690774  463 RWVESEMDELDINIALQQIELAVARIEklkslA----LGLR-----Kn-AIAHDFITFKVEERCAKLAALIAREL-T-S- 529
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2D2S_A         88 SN-EIVhl-kSG-TENMIKLGLPEQALDLFLQNRSNFIQDL---ILQIGSV--DNPTNYLTQLAVIRFQTIKKTVEDFQD 159
gi 338818093  516 SN-LRKss-sARlISLLVRLDLADHARDSFLESRRELMFKR---VRSIKCD--GDVSIYINELAVVIFTIIRHTSDWYMN 588
gi 74632700   509 DT-SNTav-tHA-LGLLVRLGHGDQARGVYLETRRNLIHKR---TRQVELL--GDIPGYIAQVAVTYFRLIRSTAEVFRK 580
gi 296415590  504 NPaKKSav-kAN-VQWLVRLDFEDRAREAFLEAKSDVIKKR---TRQVRFE--GDVPLYISQVALVQFTLIKNTVEIYNS 576
gi 575479720  493 VS-TKSqv-qEN-IDRLLRLGLGDQARDIFLTARTKTIRHR---TRHLKFD--GDVAAYMCDLAEVTFRLIRNTCDWYGG 564
gi 1022841402 561 KS-GVVr----T-TSWLLRLGQGERARETFLSARGALVRKR---ARQIKFE--GDISMYISELAMVCFTLIKNTCEWYMA 629
gi 330935411  520 NN-WFTsv-kQH-TSWVVQLGFEDRAREAYLEARGNLIKTR---SRQCIFE--GNLPDYIFQISYIYFTIIKNTVDMFQK 591
gi 573983123  518 HN-ERMkt-kRN-VSWLTRLGYHDRARETYLDARSATIHKRsrsVKRLQCIfqGDLHLYIWQLSYVYFTIIHNTVLCFQA 594
gi 576040046  525 HN-QKVkt-kAN-VSWLTRLGFEDRAREAYLEARSEIIQKR---SRQCIFQ--GSLEQYIWEIAFVYFTLIRNTVSCFQA 596
gi 171690774  530 TH-HHQrktkQN-VSWLTRLGFEDRAREAYLEARSEIIQKR---SRQCIFK--GDLHLYIWEISFVYFTIIRNTVSCFQA 602
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2D2S_A        160 IFKElgaKISSILVDWCSDEVDNHFKLIDKQLL---N---DEM---LSP---G---SIK-----SSRKQIDGLKAVGLDF 219
gi 338818093  589 AFKEn--nMASGFVTWAKQQIETFADLFRRQMD-------APN---ISE---S---TVNeclhvTATQNRKLLRDVGLDF 650
gi 74632700   581 CYTDn--HLASSIAEWAKSMVEEFVLLFARQLY---GvkpDTQ---TYQ---Q---CVS-----ITRQQAAQLSEVGLNL 641
gi 296415590  577 CFEY---RLASALVRWAKERADEYMDIFERQLHaidQ---DSN---VYG---D---CIE-----ITRLHSTMLVDCGLDF 636
gi 575479720  565 SFRDt--TMASGFMKWVTLEIVYFTDILRRQVF---N---SRQsfsVIA---D---CLS-----SALDQCQQLRDVGLDL 625
gi 1022841402 630 AFKDn--SMASGFVRWASEQVEIYAETFRRQVY---G---ADQngkVIE---E---SLE-----VTKAHGAMLRDVGLDF 690
gi 330935411  592 CFPQ---QLMSACVKWAKENIDQFNVLLKRQLS---S---VEEggnVWN---E---CLT-----LAHEHAEMLRGVGLDF 651
gi 573983123  595 CFPP---PMMSACVKWAKQEVEAFNAILARQLS---S---TER---GGP---AwteCME-----RAKEHAKKLSAVGLDF 654
gi 576040046  597 CFPa---PMMSACVKWAKEEVDAFNSILSRQLS---G---EEE---GSEiwtR---CLD-----AALEHAGTLFDVGLDF 656
gi 171690774  603 CFPP---PMMSACVKWAKEEVDAFNGILARQLS---S---TEE---GDEvwvQ---CMD-----RAKEHSDMLSEVGLDF 662

                  .
2D2S_A        220 V 220
gi 338818093  651 T 651
gi 74632700   642 D 642
gi 296415590  637 K 637
gi 575479720  626 g 626
gi 1022841402 691 T 691
gi 330935411  652 T 652
gi 573983123  655 Q 655
gi 576040046  657 T 657
gi 171690774  663 R 663
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap