Conserved Protein Domain Family
MBDa

?
pfam16564: MBDa 
p55-binding region of Methyl-CpG-binding domain proteins MBD
MBDa is a second MBD domain of Methyl-CpG-binding domain proteins. region implicated in binding the RbAp46/48 (retinoblastoma protein-associated protein) homolog p55, which is one of the components of the MBD2-NuRD complex. The MBD2-NuRD complex is a nucleosome remodelling and deacetylation complex.
Statistics
?
PSSM-Id: 318713
View PSSM: pfam16564
Aligned: 30 rows
Threshold Bit Score: 93.9076
Threshold Setting Gi: 1022775441
Created: 30-Jul-2016
Updated: 4-Aug-2016
Structure
?
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 123795317   36 VPKKIKAK-H-RTGVTSKDSMRMTSCIFAKPVTTITSYPENETRYRReEDKLTKPKQLCALKRLKKHQV 102
gi 122136086   10 CDCGKVSK-P-KPGLNISIPLRMSSYIFKRPVTRITSHPSNEVRCYPwEETLDNPQQLYWQKRLQGLQA 76
gi 780125832   98 NIHFDYSR-GtKHDASLVLPIRQTASIFKQPVTLKTNHIKNRTKADPkQDTKETPKQLFWEKRLQGLNA 165
gi 357610614   86 RAQYEYNR-GfRSDASLVPPIRQTASIFKQPVTVYKTQ-ESKVKTDLkQGTQEKPKQLFWEKRLEGLTA 152
gi 762140055   70 nhsqlrkR-M-RHDSSLVLPIRQTASIFKQPVTVIHRQ-ESKTKSELkHGPQDPPKQLFWEKRLQGIQA 135
gi 1022775441  83 kAQPDLAR-GfRNDLSVIPPIRQTASIFKQPVTIVKSQ-ECKVRHELkHGRQEKPRQLFWEKRLENLKf 149
gi 281349965   10 HDCGNQSK-P-KSRLSVSIPLRMSSYIFKKPVTRITSHPGNEVRCHPwEETLDKPQQVCWQKRLQGLQA 76
gi 354498057   10 RDCENTSK-P-KTCLNTSIPLRMSSYTFKRPVTRITSHQGNEVRYHQwEETLDKPQQACWQKRLQGLQA 76
gi 646722535   84 gTQFDYsRgV-RNDASLVPPIRQTASIFKQPVTVYKTQ-EGKVKTDFkHGPQEKPKQLFWEKRLEGLRA 150
gi 768417204   85 RAQFDY-RgV-RSDASLVPPIRQTASIFKQPVTVYKTQ-ESKVKTDLkHGTQEKPKQLFWEKRLEGLTA 150
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap