Conserved Protein Domain Family
RhoGEF67_u2

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pfam16614: RhoGEF67_u2 
Unstructured region two on RhoGEF 6 and 7
RhoGEF67_u2 is a region of natively unstructured residues on Rho guanine nucleotide exchange factor 6 and 7 proteins. The function is not known. It lies after the PH domain and before the C-terminal coiled-coil.
Statistics
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PSSM-Id: 318755
View PSSM: pfam16614
Aligned: 5 rows
Threshold Bit Score: 183.292
Threshold Setting Gi: 941819963
Created: 29-Jul-2016
Updated: 4-Aug-2016
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1043412667 298 HYSvtPRGPLEPAKLYKAWTLSCLRPAPPLRPSYALGYKERMSYIFKDSSKSPKNVKKFLP-KRKTERKPSDEDSGFRKS 376
gi 908431344  574 SSV--SRGPLEPPKISKPWSLSCLRPAPPLKPSAALGYKERMSYIMKDTSKSPRPMKKFLPgNRRKERKPSDDDIHIRRS 651
gi 556959347  436 STTgqSRGPLEPPKIPKPWTLSCLRPAPPLRPSAALGYKERMSYILKDTSKSPRTMKKFLP-KRKTERKPSDDEFILRKS 514
gi 21708146   115 ssTgqPRGPLEPPQIIKPWSLSCLRPAPPLRPSAALGYKERMSYILKESSKSPKTMKKFLH-KRKTERKPSEEEYVIRKS 193
gi 941819963  139 STM--TWGPLEPPNTPKPWSLSCLRPAPPLRPSAALCYKE-------DLSKSPKSVKKLLP-KRKPERKQSEEEFALRKS 208
                          90       100
                  ....*....|....*....|....*....
gi 1043412667 377 TVALEEDAQILKVIEAYCTGAGFQQSlCS 405
gi 908431344  652 TVALEEDAQILRVIEAYCTGASLHQS-TT 679
gi 556959347  515 TAALEEDAQILKVIEAYCTGASFQQCvSS 543
gi 21708146   194 TAALEEDAQILKVIEAYCTSANFQQ--GH 220
gi 941819963  209 TAALEEDAQILKVIEAYCTSAKTRQTlNS 237
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