Conserved Protein Domain Family
cNMPbd_u2

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pfam16643: cNMPbd_u2 
Unstructured region on cNMP-binding protein
cNMPbd_u2 is a natively unstructured region on a set of higher eukaryote cyclic nucleotide-binding domain-containing proteins. It lies between the second cNMP_binding, pfam00027, and the F-box, pfam00646, domains. The function is not known but there is a highly conserved DPDPFL sequence motif.
Statistics
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PSSM-Id: 318784
View PSSM: pfam16643
Aligned: 28 rows
Threshold Bit Score: 139.091
Threshold Setting Gi: 171694804
Created: 31-Jul-2016
Updated: 4-Aug-2016
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 121921237  401 VRRQVESVAKERLQ----------TAKDN----DVHMADI--------NgtP--NIDDLAIVDITvpRTPRR-KKSVPTV 455
gi 597577495  390 IRRQVEQTAKTRIG----------KSEDQ----DVHMVDId-------D--P--STNSLENHE-R--PITPN-RCTLPEV 440
gi 636772991  391 IRRQVEVTAKERIP----------RPESE----DTLMTDGd-------GdeS--PISRLEI-DVS--LRTPR-RGSLPQV 443
gi 572283985  392 IKSQVEQTAWHRYN-----------YRDE----DVDMADVd-------------PRRKASKSDPP--TPKLA-RLSIPDV 440
gi 831342675  389 IRKQVEATAKARYG----------RPKDE----DVLMTGVd-------SttP--SIKGLKIADRS--PKSKV-R-DLPRV 441
gi 930146626  412 LKLQVEETARERYRqsrvaaageaTSDDA----DVEMSDRr-------EggE--QMSAIGSNSNReeVLSLR-RPSVPHV 477
gi 399170258  403 LKSQVEETARLRWK----------PQDEE----DTNMTDLdat---kqSdtS--PNSEL----SA--PSTPS-KGLLANL 456
gi 531865383  403 IKSQVEETARTRYS----------GGGQGegagDIDMADVe-------RsdK--VSGLLETPVTP--PTAPSgRLSMSKF 461
gi 927415008  392 IKLQVEQTAWHRYN-----------NRDE----DVDMLDAdqqgktskSdpPtpRLARL----------------SLPDD 440
gi 589107525  392 IKSQVEQTAWHRYN-----------YRDE----DVDMADVdprrkaskSdpPtpKLARL----------------SIPDV 440
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 121921237  456 TFNDIpnHIDSPV---TPSR-REEKVMEP--FDPDPFLNVDLDN-VRSRS-RRGSL----Appt--------pesP---- 511
gi 597577495  441 TFTPS--KFASSH---TPSRaEDQDNMEP--TDPDPFLSVDMDN-MRSRTpRRGSL----Appv---------peT---- 495
gi 636772991  444 TFTPS--KPASPH---KPSRvEDKDIMEP--LDPDPFLSVDMDK-MRTRNaRRGSL----Apptp------etppS---- 501
gi 572283985  441 GFTTPf-KPLS-----ASPR-DASEVMEP--KDPDPFLSVDMEN-LRNR--RRHSV----ApptapttpttptetA---- 500
gi 831342675  442 TFTPS--KPLSPPhqtNLLE-EKDNV-EStdTDPDPFLSIDMDNmRSRMS-RRSSW----ApippefisseneseE---- 508
gi 930146626  478 TFTTPs-KPSSPT---T----DEADMRQP--SDPDPFLSVDMEN-LRNR--RRNSL----ApplpagdsssggqtT---- 536
gi 399170258  457 AFASP----GSQG---SPNK-DDFELMEP--KDPDPFLSVNMEN-LRNR--RRHSL----ApplpltaegvvtgrTngyr 519
gi 531865383  462 IFADP--STQQIG---PGSK-DDLDMMEP--KDPDPFLSVNMEN-LRNR--RRQSLalpmApptpqsepmtpgrsN---- 526
gi 927415008  441 NFATPl-KPIAGT-----PR-DDSDVMEP--KDPDPFLSVDMEN-LRNR--RRHSI----Apptt------pteaS---- 494
gi 589107525  441 GFTTPf-KPLSAS-----PR-DASEVMEP--KDPDPFLSVDMEN-LRNR--RRHSV----ApptapttpttptetA---- 500
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 121921237  512 -----HSPtksEFPKNPSANGSPLSPSPmPISK-HTSTPP------D--APL---DF--KRPRMI--RRP 560
gi 597577495  496 -----PPP---DEQTGPRTRSRSQTPTP-SRPI-HAMTPP------D--STF---RP--KRAKIF--QRR 540
gi 636772991  502 -----EEK---ATPPGPRTRSRTQTPTP-ARPApHSMTPP------D--SN----RP--KRPKTV--QRR 546
gi 572283985  501 -----PTT---PAKQNGTRTHLPEQPSP-M-----SVTAP------E--PELfdmPA--KRAKTL--SHR 544
gi 831342675  509 -----AEP---Q-------ITRLPGSSP-LSFT-HPITPPq-----E--SQL---RS--KRPRTV--HRR 547
gi 930146626  537 -----PSP---QIENNSSPLKLFTFP-P-LTAA-EEPTAAepeeerS--SRG---RF--KKARTL--AHR 586
gi 399170258  520 aslvdLIG---PTIRSGSSDTSSECGVP-S-----------------------------KRARTA--TSR 554
gi 531865383  527 -----GI---------GRSPLTDATTTP-IKLDlAAQSPP------DsgHVV---RA--KRAKTLitQRP 570
gi 927415008  495 -----STT---PTRHNGARSPLAEPSSPi------aWTAP------D--FES---DVpaKRAKTV--SNR 537
gi 589107525  501 -----PTT---PAKQNGTRTHLPEQPSPm------sVTAPe-----P--ELF---DMpaKRAKTL--SHR 544
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