2I7X


Conserved Protein Domain Family
Lactamase_B_6

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pfam16661: Lactamase_B_6 
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Metallo-beta-lactamase superfamily domain
This family is part of the metallo-beta-lactamase superfamily.
Statistics
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PSSM-Id: 318798
View PSSM: pfam16661
Aligned: 49 rows
Threshold Bit Score: 177.005
Threshold Setting Gi: 74685775
Created: 29-Jul-2016
Updated: 4-Aug-2016
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2I7X_A         19 VVRFDNVTLLIDPGWNPSkvsyeqcIKYWEkVIPEIDVIILSQPTIECLGAHSLLYYNFtshfISRIQVYATLPVINLGR 98
21_pfamImport   1 LLEIDNFCILLDCGWNAkld--islLDELKkVANKVDAILLTYPDTEHIGA---LPYAIgklgL-TGKIYGTTPIHKMGQ 74
15_pfamImport   1 ILEVGGVTILLDCGWDihfd--talLEPLReVVKRIDLVLISHPDLEHLGG---LPYAFgk-lGMRAKVYATLPVWKMGQ 74
17_pfamImport   1 LLEIDSFTILLDCGWDENfde--saLEPIKrVLPRVNAVLLSHPDVAHLGALPYLVGk----cGLTAPIFSTKPVRRMGE 74
36_pfamImport   1 LLQVDEFRFLLDCGWDENfsm--eiIDVMKrHVHQVDAVLLSHPDPIHLGAL---PYAVgk-lGLNCTIYATIPVYKMGQ 74
20_pfamImport   1 LLKVDDFTFLLDCGWDEkcs--egfIHELKkHVNKIDAVLLSYPDQLHLGAL---PYAVgk-lGLTCPVYATVPVYKMGQ 74
28_pfamImport   1 VLQVDEFKFLLDCGWDEkfd--mdfIKELKrHVNSIDAVLLSHSDPLHLGAL---PYAvg-qlGLNCPIYATLPIYKMGQ 74
5_pfamImport    1 ILQVDEVRFLLDCGWDEkfd--pnfIKELKkYVHTIDAVLLSYPDGLHLGALPYLVgk----lGLNCPIYATIPVYKMGQ 74
18_pfamImport   1 ILQVDEFRFLLDCGWDEkfd--qeyMKELKkHVPLIDAVILSHPDPLHLGALPYLVGKc----SLSCPIYATIPVYKMGQ 74
gi 224009389    5 LVEYAGMKLLLNAGWDETlpaatsvSDIIPnELPDVDAILITDSTLSSLGGLPMYFGGNqd-kKRNPPFLATYPTVKMGQ 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2I7X_A         99 VSTIDSYASAGVigpYDTNKLdleDIEISF---DH--IVPLKYSQLVDLRS-----RYDGLTLLAYNAGVCPGGSIWCI- 167
21_pfamImport  75 IFMYDLYTSRMAqeeF--DRFdldEVDMCF---DQsrFKELSYSQHYEIPD------SDGIIITPYLAGHMVGGSVWRI- 142
15_pfamImport  75 MAVYDAYISRTHegnFQ--AFdldDVDAAF---AR--FKTLKFSQHLTFSG-----RGAGVTITPYAAGRMIGAAVWRV- 141
17_pfamImport  75 MFMFESYLAKQAstsIDFAIFdldDVDAAFrlnPR--WTELRFSQRHQLLAampatAGGGIAIAAHAAGRYPGGAVWRI- 151
36_pfamImport  75 MFMYDLYQSRNNs--EDFTLFtldDVDAAF---DK--IQQLKYSQIVNLKG-----KGHGLSITPLPAGHMIGGTIWKIv 142
20_pfamImport  75 MFMYDWYQSKDNmedFDL--FtldDVDNSF---DK--VVQLKYSQSVPLKG-----KGQGLIITPLPAGHMLGGTVWKI- 141
28_pfamImport  75 MFMYDLYQSHKNvseFDLFtl--dDVDTAF---DR--ITQLKYNQSVDMKG-----KGLGLRITPLPAGHLLGGTVWRI- 141
5_pfamImport   75 MFMYDLYMSHyn--mYDFDLFtldDVDAAF---DK--IIQLKYNQSVSLKG-----KGYGITITPLPAGHLIGGTIWKV- 141
18_pfamImport  75 MFMYDLYQSRYNmeeFDLFtl--dDVDAAF---DK--IIQLKYNQSIAMKG-----KGYGITITPLPAGHMIGGSIWKI- 141
gi 224009389   84 MTLYDHHASLSLdgtHPGYsl--dDVDAVFg-eES--VITLKYSQTLNSKT-----SNKLLSITPHLSGHVVGGCYYVL- 152
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
2I7X_A        168 S-T-Y-S-E--K--LVYAKRWNHTRDNILNAASIlDATGKPLSTLMRPSAII 211
21_pfamImport 143 A-K-E-S-D--V--IVYAVDINHRRESHLEGFl---QNGLLSPELAKPTHLI 183
15_pfamImport 142 S-W-Q-T-EdnD--IVYATAYNNDHERHLRASAL--------GTLTRPSVLI 179
17_pfamImport 152 S-LgC-G-E--E--VVYAVDYNHRKERLLNRTNLdE----LLS-SQQPALLI 191
36_pfamImport 143 K-D-G-E-E--E--IVYAVDFNHKREIHLNGCS--------LESLSRPSLLI 178
20_pfamImport 142 VkD-G-E-E--D--IIYAVDYNHKKERHLNGC--------ELEKIQRPSLLI 178
28_pfamImport 142 A-A-P-GeE--D--IVYAPDFNHKKERHLNGCEI--------EKIMRPSLLL 178
5_pfamImport  142 VkV-G-E-E--D--IVYATDFNHKKERHLNGC--------ELEKLQRPSLLI 178
18_pfamImport 142 F-K-VgE-E--D--IIYAVDYNHKKERHLNGC--------ELEKIQRPSLLI 178
gi 224009389  153 K-Q-L-A-D--DteVILAPTYHHAKEKHLAG-STlHKFGVNADALLTmpgga 197
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