Conserved Protein Domain Family
REV1_C

?
pfam16727: REV1_C 
DNA repair protein REV1 C-terminal domain
This is the C-terminal domain of DNA repair protein REV1. It interacts with REV7, POLN, POLK and POLI.
Statistics
?
PSSM-Id: 318851
View PSSM: pfam16727
Aligned: 13 rows
Threshold Bit Score: 108.257
Threshold Setting Gi: 675879080
Created: 29-Jul-2016
Updated: 4-Aug-2016
Structure
?
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 122106856   511 EHLQVTPESSPMKERPEVGATTTPQK--------P-----PA-----PeveENILLRSDWRTLLSAWVESGDE--PEDED 570
gi 556995149  1146 DPGPCSSSHLDLPVSQSKLSNCPPQQ--------G-----PN-----L---AGAVEFADIKTLLKEWVTTISD--PMEED 1202
gi 768910153  1205 EICPSTSTAK--SNISEPSSKILPRP--------P-----PT-----L---AGACDLTDIKTLLREWVTTITE--PMEED 1259
gi 158295033   913 EPLLVTPDSSPAKELRTPTKGVVVAAapdvasteP-----SR-----D---PNILRRKNWRELVEEWINSAEE--PYEYD 977
gi 170042914   903 ERLQVTPEASPVKAEQIVAEEDDEG--------------------------ENVLLRPNWRQLLTAWVESGDV--PEPVD 954
gi 685942427  1071 EKTHNTHTEQP------TITHKSNMK--------A-----QRskaavL---MHRVDMGDIVSVVEQWLDTFHTqgPLARD 1128
gi 588254886   879 THTISAQTSVKAQQVSNRITKKSQLI--------ArpsviPM-----L---MRKTDIKDVLNVVESWLDIFRTrgPHASD 942
gi 699246351   882 DDVTICEGKNDNTKTERKISKPS------------------------L---GGATTTAEVRDVIRKWTRAYSQefPLDSD 934
gi 675879080   171 QQLDSLKAKSELDENKNHFS--------------------------------RFTSLQDIKNEIKMWTDFSSA--PNEYD 216
gi 1033375937 1064 EPAQITANTASTSISQPLLSAAAKPQ--------A-----PN-----L---AGAVEFNDVKALLKEWITTISD--PMEED 1120
gi 360045368   879 EDRHNTNRALEIQKNVTAMEDPSGL--------------------------FTNKTLTELQQIFGDWITSEAV--PQNED 930
gi 808876672  1255 ENNPSTSASK--PDVPETLSKYIPRP--------A-----PA-----L---AGACDLTDIKTLLREWVTTITE--PMEED 1309
gi 556995140  1149 DPGPCSSSHLDLPVSQSKLSNCPPQQ--------G-----PN-----L---AGAVEFADIKTLLKEWVTTISD--PMEED 1205
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 122106856   571 VTIIAGNARDLVnGKR--LHELHLALRFLFRILDER--------E----------NCRWHRAYVRIVEAVQVVMLEIYRC 630
gi 556995149  1203 ILQVVKYCTDLV-EEKd-LEKLDLVIKYMKRLMQQS--------V----------ESVWNMAFDFILDNVQVVLQQTYGS 1262
gi 768910153  1260 ILQVVKYCTDLI-EDKd-LEKLDLIIKYMKRLMKQS--------V----------ESVWSMAFDFVLDNVQVVLQQTYGS 1319
gi 158295033   978 VLLLAENGLELLsDNKs-LDQLYLFLRYLHRLVKET--------A----------SCFWHRAYCSVVRPIQEQMLTMYGR 1038
gi 170042914   955 VDMIAAGACDLI-ERKm-LYELQQALRLLNRTIGEQ--------Vg--------gGCGWHGAYCRIVERVQVGMVAGYGT 1016
gi 685942427  1129 VDRIKLYMQKSLtEDTegMAKTRVLLKMWKRKQAEW--------VygsevdavavDSLWQHAFDDVKQCVDEIVMSKWGC 1200
gi 588254886   943 VQRIKVYVVKLLkQDTdgMSKTRRILKLWKRKNDDF--------Lpvld---ldlSEKWQNAFANVKQTVDEIVQEKYGS 1011
gi 699246351   935 IEDIINYLCTLVnHVRn-LESTELILRTIRRYIGFVieqnenveM----------QTAWLVAYSQILCAVNKKVENLYGG 1003
gi 675879080   217 VCHFTEYLMSLL-ESHd-TRRVFLILKYIQRLDN----------L----------EECWQVRLKTVVTTVQAVVRSLFSG 274
gi 1033375937 1121 ILQVVKYCTDLI-EEKd-LEKLDLVIKYMKRLMQQS--------V----------ESVWNMAFDFILDNVQVVLQQTYGS 1180
gi 360045368   931 VQILTDYLSSLVnTN---LERIRSVLILLDRLITKLah-----pP----------DGSWRKAYQSILDTLTESIKEKYSG 992
gi 808876672  1310 ILQVVKYCTDLI-DDKd-LEKLDLIIKYMKRLMQQS--------V----------ESVWSMAFDFILDNVQVVVQQAYGS 1369
gi 556995140  1206 ILQVVKYCTDLV-EEKd-LEKLDLVIKYMKRLMQQS--------V----------ESVWNMAFDFILDNVQVVLQQTYGS 1265

                   ....*
gi 122106856   631 -KMAV 634
gi 556995149  1263 -TLKM 1266
gi 768910153  1320 -TLKI 1323
gi 158295033  1039 -RLAV 1042
gi 170042914  1017 -KLAV 1020
gi 685942427  1201 -RLSV 1204
gi 588254886  1012 -NLSI 1015
gi 699246351  1004 aqfql 1008
gi 675879080   275 -QLKL 278
gi 1033375937 1181 -TLKI 1184
gi 360045368   993 fNLKL 997
gi 808876672  1370 -TLKV 1373
gi 556995140  1266 -TLKM 1269
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap