4DGW


Conserved Protein Domain Family
SF3A2

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pfam16835: SF3A2 
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Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11)
SF3A2 is one of the components of the SF3a splicing factor complex of the mature U2 snRNP (small nuclear ribonucleoprotein particle). In yeast, SF3a shows a bifurcated assembly structure of three subunits, Prp9 (subunit 3), Prp11 (subunit 2) and Prp21 (subunit 1). with Prp21 wrapping around Prp11.
Statistics
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PSSM-Id: 318934
View PSSM: pfam16835
Aligned: 96 rows
Threshold Bit Score: 61.397
Threshold Setting Gi: 403218054
Created: 29-Jul-2016
Updated: 4-Aug-2016
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4DGW_C       114 GSVGXAIQVNYSs-----EVKEnsvdsddkakvP-------PLIRIVSGLE--LSdTKQ-KGKKFLVIAYEPFENIAIEL 178
gi 74697600  100 GRRGHGIVVNYEla---eEM---------------------PQYRFVNSLEqnVE-EYD-ESFRYLVFVCRPYENIGFKF 153
gi 74609111  155 GNKGIAVMLEFEesdktaDVLNad----------------rPYARIVSGLE--LNtSAQ-KDKRFLVVAYEPYQNVAIEI 215
gi 74693654  153 EHIGIAVRVDYKve---gTAASgd-------eeEp------PCLRILSGLE--LPgAED-DDKKYLVVAYEPFENIAIEI 213
gi 74604915  148 ELFGIAVKVRYGke---qQIHSae-------kdEf-----iPYLRIVSDFE--LDkPDP-KNVKYLVVAFEPFENVGIQI 209
gi 403218054 158 HRDGLAIRVEYSg--------------------AphsrdppPFIRIMSSFE--LPgDDNnNKGKTLIIAYPPFNNVGVPL 215
gi 363753292 175 NDIGMAIRVDYSve---gVIVTde--------dEl------PFLRVISGLE--LPgTDN-DDKKYLMVAFEPFENIAIEM 234
gi 255712635 150 NSRGIAMRVIYTnp--epSEDGgd----------------rPYVRIMSSLE---FtREE-SDKKYLIIAFEPFKAIAIEI 207
gi 367013534 153 NSEGVAIRVDYDed---gAIADes---------------itPMIRIVSGLE--LQeAEK-KDRKYLAIAYEPFEIVAIEI 211
gi 159112716 140 GKSGYCVSLWCP------KMKVg-----------------iPRYRIVSTYDqsIE-PVS-PDKQYIVISCHPYRSVGVCI 194
                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*
4DGW_C       179 PpNE-Ilfsenndx-------dnnndgvDELNKKCTFWDAISKLY 215
gi 74697600  154 EnKE-I----------------------DELs-iYEDVDEETGTY 174
gi 74609111  216 PnDReIvmngyqpq-------sdeeifvDTLNRQCTFWIENQRQF 253
gi 74693654  214 P-DKeIvmskrq----------savesiDELNGRCSYWDRDDKAF 247
gi 74604915  210 P-SDeIelndydp---------sdslalDELNRKCTYWDQDNGDF 244
gi 403218054 216 DaTRdVefdvdvhegnisvetptgkiavDRTNAQLTYWDAPNGLf 260
gi 363753292 235 P-NKeIimnnata---------glkksvDELNTRCGFWDRDDRAF 269
gi 255712635 208 P-NEeIltnsaafn-------tsgaksvDDFNSKFTYWDEDNQTl 244
gi 367013534 212 PsDRqIkmdkle----------tirdsvDEVNSKSTFWDPVHGKF 246
gi 159112716 195 MnQP-I----------------------DTAt-vYEEFDSLTETY 215
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