3N0K


Conserved Protein Domain Family
Inhibitor_I66

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pfam16850: Inhibitor_I66 
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Peptidase inhibitor I66
This family of serine protease inhibitors has a beta-trefoil fold and inhibits trypsin and chymotrypsin.
Statistics
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PSSM-Id: 318946
View PSSM: pfam16850
Aligned: 17 rows
Threshold Bit Score: 142.899
Threshold Setting Gi: 748497041
Created: 29-Jul-2016
Updated: 4-Aug-2016
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3N0K_A         1 MS--IKPGTY-EVTSK----V-NGLHVGRPLAEDRSLLPKRIRVL-PEDNNSGNs--WVVEKDdDa--YILYC--KGAPV 65
gi 748484507   1 MS--LESGIY-TIKCK----L-NDNLVGRHLVEDRSGNPKPVYAL-GAGNEPPQ---WVVEKCeEg--YILSN--NGGRA 64
gi 215474579  43 MP--LETGYY-XIKNR-------TNYXGHS--DEEPLLPQRVITL-PGGVHAPK---WFVKKEdDg-rYIIKI--DDHPT 103
gi 748526442  14 VV--LQSGNY-SIATVrdptG-AQFYLSRSPSEDRSLLPKPVLVL-PKPVTRSP---WKITRNsDg-tYTIEN--GGAPV 82
gi 336366640  58 MSrkLKTGTY-IIRSVa---V-KDGCIGRSKREQQDLAPKKVFSL-PAHHDVQQ---FVVEALdNg-rYQLWA---GSPT 124
gi 748521936   1 MS--LPSASYfIIGSY----GsYQYSVGRAPAEDKSLNPKQVYLLrPSAVGMTP---WVLIRTpHg--YVLKI--KEAPT 67
gi 748497041   1 MS--LPTAYYfMMGSH----RdYQYSIGRSPFEDHSLNPKPVWLLrPSAEGFTP---WLLTKTaRg--YVFTV--KDTPT 67
gi 597936174   1 MSv-LPSDDY-IIRNV----A-FEGSVGTLHSSGES--PRPVAMF-PPSEIATK-----VEVSnHgglYNIKV--TGTDT 63
gi 568448929  17 PP--LSTGLY-TVRTV----P-SLQIVGRNIVEEDSNNPKVINGQ-PLGVPINDnttFLFRRVgGd-tFFISCgrDGGRV 86
gi 170115955   1 MP--ISEGDH-YIRNK----G-FGAYVQRALNEDTSLNPKSVIAV-PPGVEANL---WYITK--EgdfYVLKD--KGAPA 64
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3N0K_A        66 APQEGKLFADL-------LGNM--EDKKWIVTHQPQHGENVFTVVNASTEHGWVV----P-A-DAEELQQVEVRPLIAAP 130
gi 748484507  65 ASIDDKLFAIL-------MEEEfdSAENWVIEAQPHQGENLYTVKTKSQSKAWSQtt-eV-G-SEPDTFIIAVDYFTVRE 134
gi 215474579 104 AKIDNKVFAIT-------VDRG--KFDYWYIVADERGGKDSYVITTTERYDGWVA----P-D-SEKPYEQSKCGKLCSKN 168
gi 748526442  83 VNIKGQLFAQL-------QAQAg-VETRWRITSVHWQGRDQFIIESVDRAAGWSLkttdA-A-SVFSFVQPEIKPLASTR 152
gi 336366640 125 ATVDGHLSAIL-------LSSP--PPEEWNIVYQPS--QKAYTIETASRDRSWTI----P---SKEGFVQVAVRPST--- 183
gi 748521936  68 GIVNDAVVAILn------LNLT--RYVEWGLEPVPG-EQDHFRIRGPNG-QYWTV----D-DrDTQNGRRIVLREGG--- 129
gi 748497041  68 GAEGNSVVAILd------NNRT--PVVEWIVEPVPN-EQDRFRIRNTNR-QYWTV----DgS-NTQNGYKIVLRREG--- 129
gi 597936174  64 AVIDGKVFGIF-------RG----TSEKWALEYQPQ--YDAYIVQATSQNGAWTV----P---NGGSHTQVAVAPIDASP 123
gi 568448929  87 VEMEGKVVAVFsdvpedpFEYF--VNPRWIIQRQPQHGDDIYTIESENGYWGWVM----P-T-ENPQYTPVRVRQLAATA 158
gi 170115955  65 FAKDNLVFVSV-------AEEYk-VDVKWRLTEIPNEGRNVYLIESVNKHGGWVL----P-T-E-EPYTQVAFRPLIVGP 129
                        170       180
                 ....*....|....*....|
3N0K_A       131 SYPPRY----PATELFTFTQ 146
gi 748484507 135 SLPVQY----LPQNLFEFVP 150
gi 215474579 169 LNLDQLiythDGGKLRSVQK 188
gi 748526442 153 SIPPQY----QASARFVIQR 168
gi 336366640 184 RPPPRY----PENELFTFEa 199
gi 748521936 130 ----------EGSQTFTFLR 139
gi 748497041 130 ----------EGSQIFNIFR 139
gi 597936174 124 DV--------YKTFLFTFEg 135
gi 568448929 159 TMPPRY----PPNQLWVIER 174
gi 170115955 130 REPPFY----PPNQLWVITP 145
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