Conserved Protein Domain Family
DUF5096

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pfam17019: DUF5096 
Domain of unknown function (DUF5096)
This is a family of microsporidial sequences of unknown function. There is a well conserved Asp residue towards the C-terminus which may be functional.
Statistics
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PSSM-Id: 319082
View PSSM: pfam17019
Aligned: 10 rows
Threshold Bit Score: 175.997
Threshold Setting Gi: 269859784
Created: 1-Aug-2016
Updated: 4-Aug-2016
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74621428   158 TSEENYYRMMERAFSHFGPLEEEFCSIAARQAYRIFSTYFe----SSSADVEIFISGDDVFAGIGFILGRLLLH--S--G 229
gi 906374634   84 ISMDLYNKVIDLSDTLYGPSRGEVIYSGARGVLHLFVNIF-----KFMDKKFVVYTGAGIFSEIAVVLGRLSML--Y--G 154
gi 667640334  120 LKESDMYMLLYEAFNVFGPLEDHFIYTIACSLKKFLKDIA-------TASIKIIIGSDDIFGRIGLSFARLVLDraQ--K 190
gi 484852774  144 IPYSDYQSLLSLSFSRFGPTKEEFISISSLNLFKLLKSYF-----SLNSKIDIILGENPLYNSIGLTLGRLLLN--N--D 214
gi 667631961   98 MTSEQRKSIIREAYDNYGPSKEEAASIAACYSINFFKNNFfgnkeSHSMKIGVIIQKDDWYAQVAFNISRLLMA--Q--G 173
gi 484857537  148 IPYSDYQSLLSLSFSRFGPTKEEFISISSLNLFKLLKSYF-----SLNSKIDIVLGEDPLYNSIGLTLGRLLLN--N--D 218
gi 300708805  127 ISLSQYYSFLNDCFTLYGPTKEEFCTSVSLSIFKVLKSRI-----S-SKEIMIKLGTNTLYNCIGYILGRLLLV--K--G 196
gi 523776902  158 FNYEKRKALLSRITNFLGPPEKILAGILSYNMSRLLYNLFr----GKNLKVNIITKGTDIYNTIGYIMCRNLDG--TdiH 231
gi 269859784   74 LNEQEMYNLFYDAFNTYGPTEDQFIIQGAIGIL----KII-----KDKKKIKIIIGSDDVFGRIGLCLARLLLQ--K--K 140
gi 1027186156  84 ISMDLYNKVIDLSDTLYGPSRSEVIYSGARGVLHLFVNIF-----KFMDKKFVVYTGAGIFSEIAVVLGRLSML--Y--G 154
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74621428   230 ----K-MSSIVCNESLVKNARYRQSYLNSGGVITSRPRGEPSIHIYACNKTLIPVqp----kDSAK--GFLYLDT-P-GF 296
gi 906374634  155 ----T-DVTIIPSVRTQRLTRELFYYESNGGVVSNKRKDQTIVIIADTDAKEEMT-------KNAE--RVIFLGD-Y-KN 218
gi 667640334  191 ----V-SIELRCDIYDVNTIRYKSVFENSGGCFNQYSNESVFTLILFAANRNFNFcl---gdYTAG--HVLLLDI-P-Sv 258
gi 484852774  215 ----Y-DIRVIGSPRNLEIVNYHYLYRENKGITLKKEREDNEFVIDCDNKSRCNI-------NNKK--VIFTFGLpP-SN 279
gi 667631961  174 ----YyPELIMLCSVNCKIVRQLFISKKERQKKKDSLEGSYDLSIVVCDNANILKqe----sFKSN--STVFIGV-P-EN 241
gi 484857537  219 ----Y-DIRVIGSPRNLEIVNYHYLYRENKGITLKKEREDNEFVIDCNDKSRCNI-------NNKK--VIFTFGL-PfSN 283
gi 300708805  197 ----Y-SVGIQEGKEDIEVQPYKFIFYNN----FKENIVSNKVCVNLSe------------eYIEN--YDLVFGV-N-S- 250
gi 523776902  232 ----T-ELIDLNQFKNFKVAEEIQSLSYN----KKMNNIKIDYSVTLFAMNRDELktidykkYTTR--HYIFCDV-N-EK 298
gi 269859784  141 dthkI-TVVVLCNIKNIDTVKYKYMYLNNGGIISLLNDNNEVDQIIFASNRNFEFqk----iCHGEqvVYLYFDV-P-Ei 213
gi 1027186156 155 ----T-DVTIIPSVRTQRLTRELFYYESNggvvSNKRKDQTIVIIADTDAKEEMT-------KNAE--RVIFLGD-Y-Kn 218
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 74621428   297 ciEEKETKIGLCFGSVPACFRRFNGIMYFVDIEYPTALYEEFGLGR-PIKSKIHK 350
gi 906374634  219 --IETPNKEVIFFGVPVRDPAEFTGNAILCDVGLSSKIFTKFNIRKySPKLLQKI 271
gi 667640334  259 --IGFQNFTGLGLGFIPEHFANCNKFYYLIDVGFGKTLAKKYKLPQdFKNSLVKI 311
gi 484852774  280 t-NNINNFIHIALGLGILEFVKDLKEYFLIDGMINERIYKKIGRTRkGMKSINRI 333
gi 667631961  242 a-KSSSKTYAIFYGPYDVEYKKFGGGLVFVNPGFGKRTLMRMGLDHyPSCGYIVH 295
gi 484857537  284 t-NNINNFIHIAIGLGILEFVKDLKEYFLIDGMINERIYKKIGRTRkGMKSINRI 337
gi 300708805  251 ---KYPNCINLMLGCVIEECQN-DGEGYLIDINASNKVYEKYKVRKiFDKTGIIR 301
gi 523776902  299 e-FKDKFVMSFIFGGIPMEINSIKGRVYYIDGGYNGKTRSLLEMDKeCFKDGYVL 352
gi 269859784  214 --QPFRKALGVGFGFTPNTFSNCKSHFYIIDMSFSNVLYNMYNIKEtFNYSVIRK 266
gi 1027186156 219 --IETPNKEVIFFGVPVRDPAEFTGNAILCDVGLSSKIFTKFNIRKySPKLLQKI 271
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