Conserved Protein Domain Family
Nod1

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pfam17114: Nod1 
Gef2-related medial cortical node protein Nod1
This is a small family of fungal proteins that are involved in cytokinesis, the last stage of the cell-division cycle. Nod1 co-localizes with Gef2 - RhoGEF - in the contractile ring and its precursor cortical nodes. Nod1 and Gef2 interact through this C-terminal region of each, this interaction being important for their localization.
Statistics
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PSSM-Id: 319136
View PSSM: pfam17114
Aligned: 6 rows
Threshold Bit Score: 196.113
Threshold Setting Gi: 1175410
Created: 31-Jul-2016
Updated: 4-Aug-2016
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1723553     59 MVCLSTSIAENPYQ-SLSLESVPSKILFGSFLFYVKDRIPEKAGYIIEEQFCKRL---QQIDYDAYSfspkECN-EKLKN 133
gi 1175410    824 GDELYDNILKETFN-EELLSHYPPNIIYATFQKYLSSFINRKFGVLLSSSFIQQLntvENLNLSFNS----TDAvYHLKK 898
gi 213404708   39 MMAVSEEVDKSSENvKALLQNLPVKILFGSFLFFVKDKAHAHAGHVLSEKLCNEF---LSLPLDLNNkslfSRNvEIIQT 115
gi 213402601  819 VRKIYDAVTKTPKR-EYVVMGSRPKLIFAAFKNYLSNYLLKKAGYLLPAILFQRLsvvENLDLSLNS----EKAiQLVRD 893
gi 891602274  824 LDILLEDILKESPE-FKRIQKLPEAQIYLLFWKYLKLFVVRKYGSLLPSMFIQRL---SNNGYIGFSydlkVSL-QQIQS 898
gi 891596612   61 MIKLSFLIADSPYR-PISLESVPSKILFGSFLFYVKDKIYEKAGHILDRPFCFAL---RKLVSDNSNln-hEFFlQQVKS 135
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1723553    134 IFSEFSQMKLKMLSVFFSIVQILLPKLS-GDYQEHVqfFASISAVVAPRGYVFEIYHAVEHLSLEAREVFQ 203
gi 1175410    899 ILQDLPESSLKILENIFSIASDLLLRLPlKDQCDFV--TKQLAIALAPSMFGSNAVELVYYLAYHSDRIFG 967
gi 213404708  116 LTEELPPGVFSLLQAFFTTVQEVYQKLD-GDYQENIqfFASISAVVCPRKCVHKMYPIVEFISIATPYLWK 185
gi 213402601  894 LLHELTETSNALLEIVMSITSELLLRLPrKDQCDHV--LEAVAAAISPSMFGYTARQLVQFIAYNSEELFG 962
gi 891602274  899 CLQELPQQNLRILDVVLNIVSELLLRLPlRDQCETL--IEQMASVLSPPLYRNSAIEVIRFMTYYYDQLFK 967
gi 891596612  136 NFLSLPKIKIKMLSVFFSIVQIVLSKLR-GGSHERVqfFASIAAVILPKEQINDMYQLVEYISLNAQKIFQ 205
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