2OT2


Conserved Protein Domain Family
hypC_hupF

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TIGR00074: hypC_hupF 
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hydrogenase assembly chaperone HypC/HupF
This protein is suggested by act as a chaperone for a hydrogenase large subunit, holding the precursor form before metallocenter nickel incorporation. [SS 12/31/03] More recently proposed additional function is to shuttle the iron atom that has been liganded at the HypC/HypD complex to the precursor of the large hydrogenase (HycE) subunit. . Added metallochaperone and protein mod GO terms. [Protein fate, Protein folding and stabilization, Protein fate, Protein modification and repair]
Statistics
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PSSM-Id: 129184
View PSSM: TIGR00074
Aligned: 10 rows
Threshold Bit Score: 91.2782
Threshold Setting Gi: 585286
Created: 7-Oct-2014
Updated: 23-Jan-2015
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2OT2_A         1 MCIGVPGQIRTID--GNQ------AKVDVCGIQRDVDLTLV--GscdengQ-PRVGQWVLVHVGFAMSVINEAEARDTLD 69
gi 123938      1 MCIGVPGQIRTID--GNQ------AKVDVCGIQRDVDLTLVgsCde--ngQ-PRVGQWVLVHVGFAMSVINEAEARDTLD 69
gi 3023998     1 MCLALPGQVVSLM--PNSdpllltGKVSFGGIIKTISLAYVp--------E-VKVGDYVIVHVGFAISIVDEEAAQETLI 69
gi 2495445     1 MCLAIPCKVVEII--EEDge--kyAIAEYKGVKQKAKLTLLd-------kE-VKIGDYILIHTGYALEVLSEEDAKLSLE 68
gi 2495443     1 MCIGIPLQVLECA--PGR------ALCGDDREARWIDTRLIe--------P-PAPGDWLLVFLGAAREALDAERAAQIRD 63
gi 123741      1 MCIGIPMRVVVGS--EFI------AQCERHGAISSISLMLVg--------P-QAPGTHLLTHLGSAIRVLDADEARAIDD 63
gi 585286      1 MCIGVPGQVLAVG--EDIhq---lAQVEVCGIKRDVNIALI--Ceg--npA-DLLGQWVLVHVGFAMSIIDEDEAKATLD 70
gi 499181326   1 MCIAIPGRIERID--YPI------AIVDFKGLKKEVRIDLL--E------N-PQIGDYVLVHVGMAIQKVDEEEAKKTWE 63
gi 446257588   1 MCLAIPSKVIAIK--DNV------VLLETLGVQREASLDLM--G------EsVKVGDYVLLHIGYVMSKIDEKEALESIE 64
gi 499179717   1 MCIAAPAQIIEIDseDNI------ATVDFGGVRQQVKLDLV--D------D-VEEGKYVLVHSGYAIEVMSDEAARESLE 65
                         90
                 ....*....|...
2OT2_A        70 ALQNMfDVEPDVG 82
gi 123938     70 ALQNMfDVEPDVG 82
gi 3023998    70 DLAEMgV------ 76
gi 2495445    69 AWEELfKALEEME 81
gi 2495443    64 ALCAL-QAVQAGD 75
gi 123741     64 ALAGLaEAVEGra 76
gi 585286     71 ALRQM-DYDITSA 82
gi 499181326  64 LLER--VADETGN 74
gi 446257588  65 LYQEMiARMNETQ 77
gi 499179717  66 AWDELlKALEEED 78
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