Conserved Protein Domain Family
mreC

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TIGR00219: mreC 
rod shape-determining protein MreC
MreC (murein formation C) is involved in the rod shape determination in E. coli, and more generally in cell shape determination of bacteria whether or not they are rod-shaped. Cells defective in MreC are round. Species with MreC include many of the Proteobacteria, Gram-positives, and spirochetes. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Statistics
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PSSM-Id: 129323
View PSSM: TIGR00219
Aligned: 4 rows
Threshold Bit Score: 345.692
Threshold Setting Gi: 221217875
Created: 7-Oct-2014
Updated: 23-Jan-2015
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1171019     1 MKpiFGKAPPLGIRLLIAIFASIALILADGRNSSITKARSAMETAIGGLYYLANSPRSILDGISENLVDTNKLQIENKVL 80
gi 127301      1 MKpiFSRGPSLQIRLILAVLVALGIIIADSRLGTFSQIRTYMDTAVSPFYFVSNAPRELLDGVSQTLASRDQLELENRAL 80
gi 142856      1 ---mpnkrlmllllciiilVAMIGFSLKGGRNTTWPEKVIGDTTGVFQNIFHT--PAEFFAGIFENINDLKNTYKENERL 75
gi 488737023   1 MN--FLVKFKNFIKVLLVLIVSLVFMIHDS--SSIQKRRSDNFLFFTLNSYIQSRMHGVFSFISNVFKTVN--EYKNYKD 74
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1171019    81 RQQLLEK-NADLLLLDQ----LKVENQRLRLLLNSPLRTDEYK-KIAEVLTAETDIYRQQIVINQGKKDGAYVGQPVID- 153
gi 127301     81 RQELLLK-NSELLMLGQ----YKQENARLRELLGSPLRQDEQK-MVTQVISTVNDPYSDQVVIDKGSVNGVYEGQPVIS- 153
gi 142856     76 REKLDGQ--TQYEAKLQe---LEEENKSLRDELGHVKSIKDYKpILATVIARSPDNWAKQVTINKGTQQNVAFDMAVTN- 149
gi 488737023  75 KIEFYKKrIQQLEIVTQniqsLRQENVRLKEQLNFYSSSSSDF-ISAEIIYLNYSNISTLMAINKGFNDGIEKDMIAVAy 153
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1171019   154 -E--KGVIGQIISVGEN--TSRVLLLTD--VTHSIPVQVLR---NDVRVIASGT---GHTDELSLDNVPRSVDIEKGDLL 220
gi 127301    154 -D--KGVVGQVVAVAKL--TSRVLLICD--ATHALPIQVLR---NDIRVIAAGN---GCTDDLQLEHLPANTDIRVGDVL 220
gi 142856    150 -Ek-GALIGKIKSSGLNnfTSAVQLLSDpdRNNRVATKISGkkgSKGYGLIEGYdkeKKRLKMTIIERKDKQDVKKGDLI 227
gi 488737023 154 qDgfSGLVGKVVKVYSN--TAKILPLTN--YENFVSARIQS---SRFIGLIEGNg-yGKKLEMNYVNRLAEKDLKIGDSI 225
                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1171019   221 VTSGLGGRFLEGYPVAVVQSVSRDSSNYFAIVKAKPLALLERLRYVLLLWPsnldISKvKSISPEE 286
gi 127301    221 VTSGLGGRFPEGYPVAVVSSVKLDTQRAYTVIQARPTAGLQRLRYLLLLWGa--dRNGaNPMTPEE 284
gi 142856    228 ETSGTGGVFPEGLTIGEVTDIESDSYGLTKVAYVKPAADLTDLNNVIVVNR----DVP-TVDTEEE 288
gi 488737023 226 VTAGFS-EYPVGIYIGKITNFHILDYNSLLKIEVEPAIVLDKLEYVFLVKN--------NKEIGE- 281
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