1QYA,1YM5


Conserved Protein Domain Family
PhzF_family

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TIGR00654: PhzF_family 
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phenazine biosynthesis protein PhzF family
Members of this family show a distant global similarity to diaminopimelate epimerases, which can be taken as the outgroup. One member of this family has been shown to act as an enzyme in the biosynthesis of the antibiotic phenazine in Pseudomonas aureofaciens. The function in other species is unclear. [Cellular processes, Toxin production and resistance]
Statistics
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PSSM-Id: 129739
View PSSM: TIGR00654
Aligned: 6 rows
Threshold Bit Score: 455.853
Threshold Setting Gi: 18202011
Created: 7-Oct-2014
Updated: 23-Jan-2015
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1QYA_A       11 LKPQVYHVDAFTSQPFRGNSAGVVFPADN----LSEAQMQLIARELGHSETAFLLH--SDDSDVRIRYFTPTVEVPICGH 84
gi 18202011   2 KEAEVLKYEAFTSSPGKGNPAGVVLQGDD----YTEDEMQIIAERAGYSETSFIRK--SESADLELRYFTPGHEMNLCGH 75
gi 731643     3 LMVPFKQVDVFTEKPFMGNPVAVINFLEIdeneVSQEELQAIANWTNLSETTFLFKpsDKKYDYKLRIFTPRSELPFAGH 82
gi 18202346   1 MRYGFYTLDVFTDQLFGGNPLAVFPDAEG----LTDGQMQKIAAEINYSETVFVLPpvTETGNFRLRIFTPKRELDFAGH 76
gi 2506666    1 MKPQVYHVDAFTSQPFRGNSAGVVFPADN----LSEAQMQLIARELGHSETAFLLH--SDDSDVRIRYFTPTVEVPICGH 74
1YM5_A        3 LMVPFKQVDVFTEKPFMGNPVAVINFLEIdeneVSQEELQAIANWTNLSETTFLFKpsDKKYDYKLRIFTPRSELPFAGH 82
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1QYA_A       85 ATVAAHYVR--AKVLGLG-NCTIWQTSLAGKHRVTIEKHNDDYRISLEQGTPGFEPpLEGEtRAAIINALHLTEDDILPG 161
gi 18202011  76 ATVASLYAL--CEKGMLEsGKTYSIQTKAGILPVKISEKDGRIHITLEQASPQFKP-FTGD-RKKLADALGITDEDFHED 151
gi 731643    83 PTIGSCKAF--LEFTKNTtATSLVQECKIGAVPITINEG---L-ISFKAPMADYES-ISSEmIADYEKAIGL---KFIKP 152
gi 18202346  77 PTIGTTYLLglLQPPSPLvTTTWQLEEPVGLVPVTLHYKQGQLVQTELTVAQLPQTkDSAPsCEDLALLLGLSIDQLQQG 156
gi 2506666   75 ATVAAHYVR--AKVLGLG-NCTIWQTSLAGKHRVTIEKHNDDYRISLEQGTPGFEPpLEGEtRAAIINALHLTEDDILPG 151
1YM5_A       83 PTIGSCKAF--LEFTKNTtATSLVQECKIGAVPITINEG----LISFKAPMADYES-ISSEmIADYEKAIGL---KFIK- 151
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1QYA_A      162 -LPIQVATTGHSKVMIPLKPEVDIDALSPDLNALTAISKKIGCNGFFPFQIR---PGKNE---TDGRMFS-PAIGIVEDP 233
gi 18202011 152 -LPIVFGSTGIWTAIVPLKSLEASKKMVPDNKQFPEVLVDLPKASVHPFTFEt-vHPDSD---LHGRHFSsPYSGTIEDP 226
gi 731643   153 --P-ALLHTGPEWIVALVEDAETCFNANPNFAMLAHQTKQNDHVGIILAGPKkeaAIKNS---YEMRAFA-PVINVYEDP 225
gi 18202346 157 eYEPQAYSCGLPFLFIPLINEEALNRISFNPSVWQNLLAGQWADCVYCLAPGdpsLGLSDnklIHGRMFA-PGLGIAEDP 235
gi 2506666  152 -LPIQVATTGHSKVMIPLKPEVDIDALSPDLNALTAISKKIGCNGFFPFQIR---PGKNE---TDGRMFS-PAIGIVEDP 223
1YM5_A      152 --PPALLHTGPEWIVALVEDAETCFNANPNFAMLAHQTKQNDHVGIILAGPKkeaAIKNS---YEMRAFA-PVINVYEDP 225
                       250       260       270       280       290       300       310
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
1QYA_A      234 VTGNANGPMGAWLVHH--NVLPHDGNVLrvkghQGRALGRDGMIEVTVTIRDNqPEKVTISGTAVILFHAEWAI 305
gi 18202011 227 VTGTASGVMGAYMKHYg-NAEQHKFIIE-----QGQEIGKDGKVEIEMNEAGG-HVKVNMTGTAVYSETRILKI 293
gi 731643   226 VCGSGSVALARYLQEVykFEKTTDITIS-----EGGRLKRNGLMLASIKKEADnSTSYYIAGHATTVIDGKIKV 294
gi 18202346 236 ATGSGVAALGGYLDDRldTPGSHHWQIE-----QGKALGRPSQLQLTVVKDGQgIRAVKVAGRSVLVSEGFMNL 304
gi 2506666  224 VTGNANGPMGAWLVHH--NVLPHDGNVLrvkghQGRALGRDGMIEVTVTIRDNqPEKVTISGTAVILFHAEWAI 295
1YM5_A      226 VCGSGSVALARYLQEVykFEKTTDITIS-----EGGRLKRNGLMLASIKKEADnSTSYYIAGHATTVIDGKIKV 294
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