Conserved Protein Domain Family
ETRAMP

?
TIGR01495: ETRAMP 
Plasmodium ring stage membrane protein ETRAMP
This model describes a family of proteins from the malaria parasite Plasmodium falciparum, several of which have been shown to be expressed specifically in the ring stage as well as the rident parasite Plasmodium yoelii. A homolog from Plasmodium chabaudi was localized to the parasitophorous vacuole membrane. Members have an initial hydrophobic, Phe/Tyr-rich stretch long enough to span the membrane, a highly charged region rich in Lys, a second putative transmembrane region, and a second highly charged, low complexity sequence region. Some members have up to 100 residues of additional C-terminal sequence. These genes have been shown to be found in the sub-telomeric regions of both P. falciparum and P. yoelii chromosomes
Statistics
?
PSSM-Id: 130559
View PSSM: TIGR01495
Aligned: 10 rows
Threshold Bit Score: 59.6554
Threshold Setting Gi: 124505597
Created: 8-Oct-2014
Updated: 23-Jan-2015
Structure
?
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3845101     1 MKLSKILYFFAALLALNFIAPRDYNS----MVEAKp-----------aKKLTPAERKK-RNQN--IMIYS-SIASAVALL 61
gi 18076409    1 MKVTRILYFVFFIFALNFIAPNNEHNg---YVEAK-------------KKLTPAEIKK-RNQK--LMMYS-AIASGVAVL 60
gi 18076407    1 MKVSNILFFFFAIIAVKLVYPGYVAAg---SNNNAgap--------tgKKLTDIEKKK-RNKN--IVLYS-SLASALALL 65
gi 124803442   1 MKITKIFYFFAALLALNFIAPNYF-Ng---YVEAK-------------KALTPAEKKK-RNQQ--IMLIS-GITSALALL 59
gi 574980750   1 MKVGKIFFLLNILVVCHFIISCLCRNg---QTTRGnll--------alKAIEQDLQQK-KNRKrnLILYSlGSAALIAAL 68
gi 124806685   1 MKLFKILYLIAALLAINLIAPSVCNEnvegKKKKKgc---------plRNFNFQEFRK-KHHK--AILIS-SVVSAIALL 67
gi 124507257   1 MRILKVLTLLVFLLCINVFSPCYTKNg---FLSRIkd---------rfTKFEKKMKDK-ENKK--KLLIS-ASIVGLSLL 64
gi 124801913   1 MKISKILFFFVAIIAVKLFIPGYVL-----GGSSGsg---------gvKKLTDAQKKK---KN--IIIFS-SVASVLAAL 60
gi 124512788   1 MKVSKLVLFAHIFFIINILCQYICLNa---SKVNKkgkiaeekkrkniKNIDKAIEEHnKRKK--LIYYS-LIASGAIAS 74
gi 124505597   1 MKLSNLFYVFALLISMNVFVPGFMNVl--gKNVNVdsi--------vmSKIDEMQKKK-QQQK--IIMIS-TVVTGLALL 66
                         90       100
                 ....*....|....*....|.
gi 3845101    62 IGGAVGLGIHLHKNNKGDNKK 82
gi 18076409   61 LGASIGLGVHFSKKKSPKKKV 81
gi 18076407   66 VGTGVGLGFYYKNKNDKGEKE 86
gi 124803442  60 IGAGVGLGIHYKNKNNGDEKK 80
gi 574980750  69 VVTGIGLNMYMKKKNVDSEVQ 89
gi 124806685  68 FGTAYGIGLHLNNKTFIKSIL 88
gi 124507257  65 TNLIVGFAYYNYRKNQRNQAL 85
gi 124801913  61 IGAGVGFGIYYKNHKSDNKDE 81
gi 124512788  75 VAAILGLGYYGYKKSREDDLY 95
gi 124505597  67 LGSALGFGYLSKSNKKPEVSG 87
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap