Conserved Protein Domain Family
ExbD_2

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TIGR02804: ExbD_2 
TonB system transport protein ExbD, group 2
Members of this family are Gram-negative bacterial inner membrane proteins, generally designated ExbD, related to the TolR family modeled by TIGRFAMs TIGR02801. Members always are encoded next to a protein designated ExbB (TIGR02797), related to the TolQ family modeled by TIGRFAMs TIGR02796. ExbD and ExbB together form a proton channel through which they can harness the proton-motive force to energize TonB, which in turn energizes TonB-dependent receptors in the outer membrane. TonB-dependent receptors with known specificity tend to import siderophores or vitamin B12. A TonB system and Tol-Pal system often will co-exist in a single bacterial genome.
Statistics
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PSSM-Id: 131851
View PSSM: TIGR02804
Aligned: 3 rows
Threshold Bit Score: 165.821
Threshold Setting Gi: 57167445
Created: 8-Oct-2014
Updated: 23-Jan-2015
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 57167445  14 NEGLNIVPFIDIMLVLLAIVLSISTFIAHGKIQISLPSSENATNISnNEKKLLITIDEKNTFYLNDKLADLNEVQNAIFS 93
gi 34483491   6 PEGLNIVPFIDVMLVLLAIVLTISTFIAQGKIKVDLPEASSAETKP-FDRKLEIVINADNELFVDETKVTLDELRAKLAP 84
gi 1169577    4 FDEINIIPFIDIMLVLLTVVLITASFISQGKIQVNVPKASTAVAFKsDELAKLLTVTADKQLYFNDKPISQEALEAEIAQ 83
                        90       100       110       120
                ....*....|....*....|....*....|....*....|.
gi 57167445  94 LDKKTIVELKSDKNAKFESFVKIIDFLKAKEHENFQILTEK 134
gi 34483491  85 LTKDFPVVLKSDKESKFDIFIQVVDILKAKGHENLQIVAKQ 125
gi 1169577   84 WNKDQKVTLKIDAEASFQDFVTITDMLSKNEIKNVAIVSMK 124
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