Conserved Protein Domain Family
cas_csx13_C

?
TIGR03486: cas_csx13_C 
CRISPR-associated protein Cas8a1/Csx13, MYXAN subtype, C-terminal region
Members of this family are found among cas (CRISPR-Associated) genes close to CRISPR repeats in Leptospira interrogans (a spirochete), Myxococcus xanthus (a delta-proteobacterium), and Lyngbya sp. PCC 8106 (a cyanobacterium). It is found with other cas genes in Anabaena variabilis ATCC 29413. In Lyngbya sp., the protein is split into two tandem genes. This model corresponds to the C-terminal region or downstream gene; the N-terminal region is modeled by TIGR03485. CRISPR/cas systems are associated with prokaryotic acquired resistance to phage and other exogenous DNA.
Statistics
?
PSSM-Id: 132525
View PSSM: TIGR03486
Aligned: 4 rows
Threshold Bit Score: 200.868
Threshold Setting Gi: 119455653
Created: 9-Oct-2014
Updated: 23-Jan-2015
Structure
?
Aligned Rows:
Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119455653   1 MTDNLSEHLPWWSNFFIYFKEKDQFKELRY-------------------HRDKLNTMIENSH--------WDLPTQKLFI 53
gi 75703422  345 IANNLAMGRSWWANWISFIKNKKSFKQFTD-------------------EYKGINKMIQDSE--------WDIEAQKLFI 397
gi 24197096  372 IAENLVQGKRWYYQFAKPLSWYIDTLERKRksspgsshekiwfesirrfERAELIKFMENNEi-------WNSEEEQWFV 444
gi 521967524 361 ITENLAASRPWYADFATATTAEGRFIHDYR-------------------DRDNLGALLWHERkgliamhpYLGEAEQWLV 421
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119455653  54 QAFHEALRRIYGQVAAKAKk---qEDNWIQFDREYQQIYSSLTRITDFESFQSFICQFWARASrpghLIPTLQEHWDKFL 130
gi 75703422  398 QACHEALRKIYAKIYSRTK-----EGEYAQIERENTRILSQLKRCTNTDNFRKFIAEFWGRAG----QIAILEEHWMELL 468
gi 24197096  445 KSFHETLSRLYAKEASHLNrrggsRTLGDRWKHMNEKIYRDLAQAKTSPQIRTVISDLWAKSG----RPPSLQEHTGALW 520
gi 521967524 422 QSVHLALRSRFKSIYADTKes-apATRSNRLKGERERLRLSFAGAKTPEQVRAALADLWSRAG----TNRELQEHWRDIL 496
                        170       180
                 ....*....|....*....|....
gi 119455653 131 FQDEDF-NWEQARNLALLALASYK 153
gi 75703422  469 PLTTGIgNWKVARDLTFIAMASYP 492
gi 24197096  521 KFISKD--SEYARDLSLVALASYQ 542
gi 521967524 497 QLLGPE-RWRAARDLALVALASYQ 519
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap