Conserved Protein Domain Family
COLIPASE

?
cd00039: COLIPASE 
Click on image for an interactive view with Cn3D
Colipase; a stoichiometric cofactor for pancreatic lipase, allowing the enzyme to anchor itself to the water-lipid interface and stabilizing the active enzyme conformation
Statistics
?
PSSM-Id: 119409
View PSSM: cd00039
Aligned: 12 rows
Threshold Bit Score: 122.238
Threshold Setting Gi: 149584758
Created: 1-Nov-2000
Updated: 17-Jan-2013
Structure
?
Program:
Drawing:
Aligned Rows:
 
Conserved site includes 8 residues -Click on image for an interactive view with Cn3D
Feature 1:lipase interaction site [polypeptide binding site]
Evidence:

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                      ##                     #      #                           ###     
1ETH_B         1 VPDPRGIIINLDEGELCLnSAQCKSNCCQHDTilSLSRCALKARE---------NSECSAFTLYGVYYKCPCERGLTCEG 71
gi 116898     18 VPDPRGIIIHLEDGELCLnSVQCKSKCCHRATglSLARCAPKASE---------NSECSAKTLYGVYYKCPCERGLTCEG 88
gi 116900     18 APGPRGIIINLENGELCMnSAQCKSNCCQHSSalGLARCTSMASE---------NSECSVKTLYGIYYKCPCERGLTCEG 88
gi 1169001    12 VPDPRGVIINLEAGEICLnSAQCKSECCHQESslSLARCAAKASE---------NSECSAWTLYGVYYKCPCERGLTCQV 82
gi 1169005    18 APDPRGLIINLDNGELCLnSAQCKSQCCQHDSplGLARCADKARE---------NSGCSPQTIYGIYYLCPCERGLTCDG 88
gi 1169006    18 APGPRGIVINLEEGELCLnSAQCKSGCCHHSSalSLARCAPKASE---------NSECSPQTIYGVYYKCPCERGLTCEG 88
gi 7711136    18 VPDPRGIIINLDEGELCLnSAQCKSNCCQHDTilSLSRCALKARE---------NSECSAFTLYGVYYKCPCERGLTCEG 88
gi 13384886   19 APGPRGLIINLEDGEICLnSMQCKSRCCQHDTilGIARCTHKAME---------NSECSPKTLYGIYYRCPCERGLTCEG 89
gi 14701913   17 APDPRGILINLEDGEICMnSAQCKSSCCQHFSplGVARCTRKASE---------NSECSPKTLYGIYYKCPCERGLTCES 87
gi 166157775  23 IPDEKGLIFNLDNGELCLqTAQCKSGCCHRNSgvSLARCAPKAAE---------TQKCSPLHIYGTYYFCPCESGLTCEV 93
gi 149584758  13 SGDPEGNGSPLWAGTVAL-SVCCTSRDYFSCIs-MYHHCKASMGHppgreagqtEEAEWPCTLYGMYHKCPCEQGLTCET 90
gi 117574059  23 GSLSPTKYNLLELKESCIrNQDCETGCCQRAPdnCESHCAEKGSE---------GSLCQTQVFFGQYRACPCLRNLTCIY 93
                         90
                 ....*....|....*....
Feature 1                         # 
1ETH_B        72 DKslVGSITNTNFGICHNV 90
gi 116898     89 DKsiVGSITNTNFGVCHDA 107
gi 116900     89 DKtiVGSITNTNFGICHDA 107
gi 1169001    83 DKtlVGSIMNTNFGICFDA 101
gi 1169005    89 DKsiIGAITNTNYGICQDP 107
gi 1169006    89 DKsiVGSITNTNFGVCLDV 107
gi 7711136    89 DKslVGSITNTNFGICHDV 107
gi 13384886   90 DRsiIGAITNTNYGICLDS 108
gi 14701913   88 DRtiIGAITNTNYGICLDA 106
gi 166157775  94 DRsiVGSITNTDYGYCEDQ 112
gi 149584758  91 DWtiIGAITNSNYGICLDS 109
gi 117574059  94 SK--NEKWLSIAYGRCQKI 110

| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap