Conserved Protein Domain Family
Ribosomal_L7_archeal_euk

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cd01657: Ribosomal_L7_archeal_euk 
Click on image for an interactive view with Cn3D
Ribosomal protein L7, which is found in archaea and eukaryotes but not in prokaryotes, binds domain II of the 23S rRNA as well as the 5S rRNA and is one of five ribosomal proteins that mediate the interactions 5S rRNA makes with the ribosome. The eukaryotic L7 members have an N-terminal extension not found in the archeal L7 orthologs. L7 is closely related to the ribosomal L30 protein found in eukaryotes and prokaryotes.
Statistics
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PSSM-Id: 100099
View PSSM: cd01657
Aligned: 71 rows
Threshold Bit Score: 123.406
Threshold Setting Gi: 67623361
Created: 6-Mar-2002
Updated: 17-Jan-2013
Structure
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Program:
Drawing:
Aligned Rows:
 
Conserved site includes 41 residues -Click on image for an interactive view with Cn3D
Feature 1:23S rRNA binding site [nucleic acid binding site]
Evidence:

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1              ###     ### ## #### #####        ######  ## ###                 #         
1JJ2_V         1 MHALVQLRGEvnmHTDIQDTLEMLNIHHVNHCTLVPET-DAYRGMV-AKVNDFVAFGEPSQETLETVLATRAEPLegdad 78
gi 3914728     4 LIGVIRIRGWaatPWYIQDTLSMLRLKNAFNAMIYPKD-SSIQGML-NLVSSYVTWGELNDEGLRLLVSKLEISRgk--k 79
gi 161527908   4 AVLVVRIKGQadcPYWASTTMDLLKLERKYRAVILPAK-DNLLGML-KKVQHYVAWVDLDTELAQELIDKKARKSgy-kk 80
gi 118575524   4 AYIVVRIKGQadvPHWAETTLKLLRLEKKHRATIIQSK-ENTRGML-DKVKHYVAWQEIDAGLAMELLTKRGRGPgy-kk 80
gi 18312459   12 RYAVIRLRGIpttPRDIAVTLDLLRLRRKFTMVVVKGS-PSVMGMI-QKVNDWVTWGEIDADTLAEVLRKRGRIVgd-kp 88
gi 159041624  17 IVAAVRIRGLvdvSPEVNHTLNLLRLRRRFTCSVYVLS-DSIKGML-KSVESWATWGELSRDTLIQLLRRRGRIVgd-lp 93
gi 118431008   3 LYAVIRIRGTvdvPPDIDKTLYLLRLRRRYTASIYHDSlPGLRDML-RTVEAWTTYGEIEERVLEELLRKRGRIVgd-kp 80
gi 119719153   3 LYLVIRLRGQpdrRPEEEKALELLRLHKVYHAVLVKDD-PSIKGMLeRTLSSAVTWGEINKETLVELLKRRGRITgn-kr 80
gi 11134354    4 LLGIIRIRGWakaPWYINETLNMLRLRYNFNTMVYPKT-SQILGML-NKVSPYITWGEIDPDTLKLLIINRLETVkg-dk 80
gi 15920621    4 LLGIIRIRGYagtPWYIQDTLKMLRLPRRFNAMVYEDS-SSIRGML-KIAEPYITWGELNEEGLKLLLTRLHTKIgn-lk 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                                                                 ########         ##   #
1JJ2_V        79 VDDEWVAEhtdYDDISGLAFALLSee----tTLREq---------------GLSPTLRLHPPRGGHDgvk-hpVKEGGQL 138
gi 3914728    80 VNEEYVKDk-lNVDFQSFVESIKDgkl--rlNKLDe---------------IFSLPIRLHPPKGGFKgkvsrpFRAGGEF 141
gi 161527908  81 VTPEDLKEl-gYASSAELAAALTEgk---tmLSKLk---------------PLKPWFALAPPRHGFKrstkrlYGQKGIL 141
gi 118575524  81 LTEKDLEGt-dYPGIKELADALATgk---asMSKId---------------RIKPWFALAPPRHGFKrstkkmYGQKGVL 141
gi 18312459   89 LTLEYLQKw-gWHSFEEIALAYVAgei--dsLSCGkkmrikeg-erppcipYLKPFFRLHPPRGGLNsvk-lhFSVGGDL 163
gi 159041624  94 LTDEYLKKy-gWGSVEELVDAYLKgev--ksLWCRrgegprmingkascipGLKPFFRLHPPKGGFKgsikkpYGAGGEL 170
gi 118431008  81 LTDKWVEEnlgLSGLGELAEKLVSgelhyhrLEEK----------------GVKPFFRLHPPRGGFKksikrmFRDGGEL 144
gi 119719153  81 LTEEYLKKi-gFNSFEELAEALISgk---vsLEDLp---------------GVKPVFRLRPPSGGFRgtirrnINARGEL 141
gi 11134354   81 VSDSYVKEvlkIENIDAMVKQLYEgki--ylHKLDe---------------YFKLPIRLHPPRGGFKgsvkrpYKNKGEF 143
gi 15920621   81 ITDDILKSqlkIESYNLFVKKIMDgei--klHKLDd---------------YFKLPIRLHPPSGGFKgkinrpFSVKGEF 143
                        170
                 ....*....|....*.
Feature 1                       #
1JJ2_V       139 GkhdtEGIDDLLEAMR 154
gi 3914728   142 Gyr-gDKINELIRRMV 156
gi 161527908 142 Gr--nKELATIVRNMI 155
gi 118575524 142 Ga--nRELSELVRSMI 155
gi 18312459  164 Gyr-gPLINDLIRRML 178
gi 159041624 171 Gyr-gLDINDLILRMI 185
gi 118431008 145 Gyr-gSAINELILKML 159
gi 119719153 142 Gyr-gADINNLVLRML 156
gi 11134354  144 Gyr-gDKINELMRRMV 158
gi 15920621  144 Gyr-gEKINELIKRMV 158

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