Conserved Protein Domain Family
P-type_ATPase_Na_ENA

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cd02086: P-type_ATPase_Na_ENA 
fungal-type Na(+)-ATPase, similar to the plasma membrane sodium transporters Saccharomyces cerevisiae Ena1p, Ena2p and Ustilago maydis Ena1, and the endoplasmic reticulum sodium transporter Ustilago maydis Ena2
Fungal-type Na(+)-ATPase (also called ENA ATPases). This subfamily includes the Saccharomyces cerevisiae plasma membrane transporters: Na(+)/Li(+)-exporting ATPase Ena1p which may also extrudes K(+), and Na(+)-exporting P-type ATPase Ena2p. It also includes Ustilago maydis plasma membrane Ena1, an K(+)/Na(+)-ATPase whose chief role is to pump Na(+) and K(+) out of the cytoplasm, especially at high pH values, and endoplasmic reticulum Ena2 ATPase which mediates Na(+) or K(+) fluxes in the ER or in other endomembranes. This subfamily belongs to the P-type ATPases, a large family of integral membrane transporters that are of critical importance in all kingdoms of life. They generate and maintain (electro-) chemical gradients across cellular membranes, by translocating cations, heavy metals and lipids, and are distinguished from other main classes of transport ATPases (F- , V- , and ABC- type) by the formation of a phosphorylated (P-) intermediate state in the catalytic cycle.
Statistics
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PSSM-Id: 319780
View PSSM: cd02086
Aligned: 9 rows
Threshold Bit Score: 1423.77
Threshold Setting Gi: 33352142
Created: 13-Jan-2005
Updated: 18-Aug-2016
Structure
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Aligned Rows:
 
Feature 1: P-type ATPase signature motif, 7 residue positions
Conserved feature residue pattern:D K [TS] G T [LIVM] [TS]Click to see conserved feature residue pattern help
Evidence:
  • Comment:a characteristic P-type ATPase conserved sequence motif: DK[TS]GT[LIVM][TS], in which D is the reversibly phosphorylated Asp

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                                                                                         
gi 416667      36 GLTQDESLRRLKAVGENTLgddtkiDYKAMVLHQVCNAMIMVLVISMAISFAVrDWITGGVISFVIAVNVLIGLVQEYKA 115
gi 6688837     97 GIDNDEAARRLQHHGPNKVegakglSLWTILLRQVSNSLTLVLVITMVLSFAIsDHIEGGVIAAVILLNIIVGFLQDYRA 176
gi 33352142    37 GLSNAKAERLLKQYGRNELkgqgavNPWKILLAQVANGLTAVLTIAMVVSFAVkDYGEGGVLVLVIAFNTIVGFMQEYRA 116
gi 114303      29 GLTHEEAQNRLSEYGENRLeadsgvSAWKVLLRQVLNAMCVVLILAAALSFGTtDWIEGGVISAIIVLNITVGFIQEYKA 108
gi 6688839     46 GLTPDEAKRRLEEYGKNELgeaegvQPIKIIIAQIANAMTLVLILAMAVSFGIkSWIEGGVVAFVIGLNVVVGFFQEYSA 125
gi 195540542   49 GLNKKDIESRRQEFGQNMLeggdeiSIWKIMAHQIANAMTLVLILAMGVSLGIgSWIEGGVLAGVVAINIIVGFFQELSA 128
gi 114302      36 GLTQDEFVHRLKTVGENTLgddtkiDYKAMVLHQVCNAMIMVLLISMIISFAMhDWITGGVISFVIAVNVLIGLVQEYKA 115
gi 3121791     36 GLTQDESLRRLKAVGENTLgddtkiDYKAMVLHQVCNAMIMVLVISMAISFAVrDWITGGVISFVIAVNVLIGLVQEYKA 115
gi 195540544  122 GLSEGQATTRLNEYGPNQLketnrvSATSILIRQMANALTLVLLAAMALSFGVkDWVEGGVVTAVIVTNVLIGFIQEYKA 201
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                                                                                         
gi 416667     116 TKTMNSLKNLSSPNAHVIRngkSETINSKDVVPGDICLVKvGDTIPADLRLIEtknFDTDESlLTGESLPVSKDanlvfg 195
gi 6688837    177 EQTIQALYALSAPTCKVTRsgvTSTIKAETLVPGDIVRLGvGDVVPADLRLATsinLSTDEAlLTGESLPVSKHaelvma 256
gi 33352142   117 EKTMDALRKMASPSAKVIRegiQQRISSTDVVPGDVLTFEvGDIIPADCRLMEvlnLEVDEAlLTGESVPSIKLvepilg 196
gi 114303     109 EKTMDSLRTLASPMAHVTRsskTDAIDSHLLVPGDVVVLKtGDVVPADLRLVEtvnFETDEAlLTGESLPVIKDahatfq 188
gi 6688839    126 EKTMDSLRSLSSPTATVVRggeAMVVPSGEIVPGDLVEVKmGDTLPADIRLIEaknFETDEAlLTGESLPVRKTvestfd 205
gi 195540542  129 EKTMNALRNLASPTARVIRngdGETISANEVVPGDIIELTtGDTVPADCRLIDsmnFETDEAlLTGESLPVAKDhnqiys 208
gi 114302     116 TKTMNSLKNLSSPNAHVIRngkSETINSKDVVPGDICLVKvGDTIPADLRLIEtknFDTDESlLTGESLPVSKDanlvfg 195
gi 3121791    116 TKTMNSLKNLSSPNAHVIRngkSETINSKDVVPGDICLVKvGDTIPADLRLIEtknFDTDESlLTGESLPVSKDanlvfg 195
gi 195540544  202 ERTMASLRTLSSPNANVLRsssIRQVPSAELVPGDIIHFRaGDLVPADVRLVTisnLEIDEApLTGESVPAIKTtgpllr 281
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                                                                                         
gi 416667     196 keeetsvGDRLNLAFSSSAVVkGRAKGIVIKTALnSEIGKIAKSLQGDsglisrdpskswlqnt----------wistkk 265
gi 6688837    257 rdrdvplGDRSNMVYSASTITrGRATGIVVSTGMgTEVGKIAGLLRDSnggrnkkrvdkeemgtlr-------sltvrar 329
gi 33352142   197 --kdvsiGDRINMVYSSTTVAkGRGRAIVASTGMsTEIGKISNAINETpa------------------------------ 244
gi 114303     189 mnedvpiGDRINLAYSSSIVTkGRAKGICYATGMqTQIGAIAAGLRQKgklfqrpekdepnyrrkln----kyylkvtsy 264
gi 6688839    206 --dttgpGDRLNVAYSSSTVTkGRAKGIVFATGTfTEIGAIASALNKKdskvrpvkrkpnghagphry--leaytltlgd 281
gi 195540542  209 agedvgvGDRLNMAFTSSTVSkGRATGVVVGTGMnTEIGKIADALRGAakaqkirdvkrnaygkalphhyvqagaltiwd 288
gi 114302     196 keeetsvGDRLNLAFSSSAVVkGRAKGIVIKTALnSEIGKIAKSLQGDsglisrdpskswlqnt----------wistkk 265
gi 3121791    196 keeetsvGDRLNLAFSSSAVVkGRAKGIVIKTALnSEIGKIAKSLQGDsglisrdpskswlqnt----------wistkk 265
gi 195540544  282 --phlgpADRTNLAYAGTTVTkGRAVGIVVATAMnTQIGQIATALAKKgnkedaqrpwykr----------------twd 343
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                                                                                         
gi 416667     266 vtgaflgtnvGTPLHRKLSKLAVLLFWIAVLFAIIVMASqkfdvdkrVAIYAICVALSMIPSSLVVVLTITMSVGAAVMv 345
gi 6688837    330 ngmrvllgldGTPLQVTLSKFALLLFALAILLAIIVFSVskfdvtdeVLIYGICVAVAVIPESLIAVLTIATALGTRAMa 409
gi 33352142   245 ---------qLTLLQRRLNMMAYVLMVIALILALIVFAVnkfdfnteIIIYAIALAIGVIPEGLIAVITIVQALGVRRMa 315
gi 114303     265 yvqrvlglnvGTPLQRKLTVLAYILFCIAIILAIIVMAAhsfhvtneVSIYAISLGISIIPESLIAVLSITMAMGQKNMs 344
gi 6688839    282 algrflgvnvGTPLQRKLSKLAMLLFGIAVICAIIVLGAnkfntrqeVIIYAVATGLSMIPASLVVVLTITMAAGTKRMv 361
gi 195540542  289 kinnflgtnkGTPLQRRLSQLAVALFFVAVLFAVIVFLSnnwt-dneVIIYAVATGVSMIPASLTAVLTITMAMGSKAMv 367
gi 114302     266 vtgaflgtnvGTPLHRKLSKLAVLLFWIAVLFAIIVMASqkfdvdkrVAIYAICVALSMIPSSLVVVLTITMSVGAAVMv 345
gi 3121791    266 vtgaflgtnvGTPLHRKLSKLAVLLFWIAVLFAIIVMASqkfdvdkrVAIYAICVALSMIPSSLVVVLTITMSVGAAVMv 345
gi 195540544  344 avatflgvreGTPLQIKLNKFAYVLLFLAIICAIIVFGVaefdinneVILYAIALGIGVIPESLVAVLTITFSVGAKRMa 423
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                                #######                                                  
gi 416667     346 srnVIVRKLDSLEALGAVnDICSDKTGTLTQGKMLARQIWIPrfgtitisnsddpfnpnegnvsliprfspyeyshnedg 425
gi 6688837    410 rgnVVIRKLAALEAVGGVtNICSDKTGTLTQGKMVTKKVWLAngtevevlgtthpfdstsgsvsigeevf---------- 479
gi 33352142   316 kqhALVRKLVALESLQAVtNICSDKTGTLTQGKMVVTNVWFPghdseyiisgqgyetkgdisaq---------------- 379
gi 114303     345 krrVIVRKLEALEALGGVtDICSDKTGTITQGKMITRRVWIPsygylsvdtsdannptigtvsgleaamqd--------- 415
gi 6688839    362 ernVIVRNLKSLEALGAVtDICSDKTGTLTQGKMVARGAWIPgmgtytvelgdepvnptkgdirfakqmpsevdf----k 437
gi 195540542  368 kknVIVRKLESLEALGSInDICSDKTGTLTQGKMVVRKAWVPasgtysvsetnepfnptlgevsvnnveprdak------ 441
gi 114302     346 srnVIVRKLDSLEALGAVnDICSDKTGTLTQGKMLARQIWIPrfgtitisnsddpfnpnegnvsliprfspyeyshnedg 425
gi 3121791    346 srnVIVRKLDSLEALGAVnDICSDKTGTLTQGKMLARQIWIPrfgtitisnsddpfnpnegnvsliprfspyeyshnedg 425
gi 195540544  424 esnVVVRRLDALEALGGVtDICSDKTGTLTQGKMVVRQGWSLadgkqqsfdveqtgatafepkgrvils----------- 492
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                                                                                         
gi 416667     426 dvgilqnfkdrlyekdlpedidmdlfqkwletATLANIATVfkddat-----dcwkahGDPTEIAIQVFATKmdlphnal 500
gi 6688837    480 -----sladhgmkdpeeaigekgenlkeflesIALCNNAVVtkaeea-----gtysaiGEPTEIALQTFAMRfgmgkssv 549
gi 33352142   380 -----------graiatetaledlnfrklvecCALCNTANIveasq--------gnvwGDPTEIALQVFAYKmqmgkpi- 439
gi 114303     416 ----vlkekkqemknidpsnqpsdqfipllktCALCNLSTVnqtetg------ewvvkGEPTEIALHVFSKRfnygked- 484
gi 6688839    438 stnaeksstgpvtapgelltssttrlqdflsvCSLANLATVfskeseetpgteqwharGDPTEIAIQVFASRfdfnrlrl 517
gi 195540542  442 asrnsgegevvarsgksdkvkgndrfedfmnvASLCNLATVfkdket-----hawtahGDPTECAIQTFVTRfawgrlkl 516
gi 114302     426 dvgilqnfkdrlyekdlpedidmdlfqkwletATLANIATVfkddat-----dcwkahGDPTEIAIQVFATKmdlphnal 500
gi 3121791    426 dvgilqnfkdrlyekdlpedidmdlfqkwletATLANIATVfkddat-----dcwkahGDPTEIAIQVFATKmdlphnal 500
gi 195540544  493 ------pvsvndepqpvehdqlpddirslataASLCNIAEIeqredg------swiarGDPTEIALQVFATKlqmsrdal 560
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                                                                                         
gi 416667     501 tgekstnqsnendqsslsqhnekpgsaqfeHIAEFPFDSTVKRMSSVYYnnh---netYNIYGKGAFESIIsccsswygk 577
gi 6688837    550 la-------------------ivdgqsqqqLLFEFPFDSSCKRMTVVYTstessgagdSYAYTKGALEALLplldas--- 607
gi 33352142   440 ------------------------lrktkkPVEEFPFSSDTKRMSMVYLtkl---edvLEVYSKGAEVVLTicddvmert 492
gi 114303     485 ------------------------llktntFVREYPFDSEIKRMAVIYEdqq----gqYTVYAKGAVERILercstsngs 536
gi 6688839    518 v---------------------sgsnpewqEVAEFPFDSDVKRMSVIMKntq---tqeHWAFTKGAVERVIgacvnyfds 573
gi 195540542  517 tkgtdad---------kevtekdrtaakwtQITEYPFDSSVKRMAVTYVnnq---aqeSYAMMKGAVERVLesctsaqta 584
gi 114302     501 tgekstnqsnendqsslsqhnekpgsaqfeHIAEFPFDSTVKRMSSVYYnnh---netYNIYGKGAFESIIsccsswygk 577
gi 3121791    501 tgekstnqsnendqsslsqhnekpgsaqfeHIAEFPFDSTVKRMSSVYYnnh---netYNIYGKGAFESIIsccsswygk 577
gi 195540544  561 t---------------------hgesakysHELEFPFDSTLKRMTSVYRrnsq-tvsdRIFFMKGAVEQVLacchnm--- 615
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                                                                                         
gi 416667     578 dgv--kitpltdcdveTIRKNVYSLSneGLRVLGFASKsftkdqvnddqlk----------------------------- 626
gi 6688837    608 -----------deqkvEIVAKAEALAaqGLRVLCVAKRsvngalfqagddvsaspe------------------rekasa 658
gi 33352142   493 gnl--rnisedgefmkNVTVQQEEMAkqGLRVLVIAYRqeseraigkpv------------------------------- 539
gi 114303     537 --------tleepdreLIIAQMETLAaeGLRVLALATKvidkadnwet-------------------------------- 576
gi 6688839    574 dgpdaeakpvtdefraDILKNMESFAslGLRVLALASRrlpsdgttwne------------------------------- 622
gi 195540542  585 eg----kidldekfekRVLENMEALAsqGLRVLALAHRklteaekelde------------------------------- 629
gi 114302     578 dgv--kitpltdcdveTIRKNVYSLSneGLRVLGFASKsftkdqvnddqlk----------------------------- 626
gi 3121791    578 dgv--kitpltdcdveTIRKNVYSLSneGLRVLGFASKsftkdqvnddqlk----------------------------- 626
gi 195540544  616 ----------deiarkSVIDQVEKMAsqGLRVLAFAERsmddvqfkdessrtrfasqsddldeagtisttdkklsdsada 685
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                                                                                         
gi 416667     627 nitsnrataesdLVFLGLIGIYDPPRnETAGAVKKFHQAGINVHMLTGDFvGTAKAIAQEVGILptnlyhys-------- 698
gi 6688837    659 sivperssvemhLTFLGLAGIYDPPRlESAAAVQKCQAAGITVHMVTGDHvKTATAIACEIGILrsdrlq---------- 728
gi 33352142   540 -ckwkredvesnLTFLGLVGIRDTPRiESKESVSQCHQAGITVHMLTGDHkATALSIAREVGILeplsaskrstskrgvk 618
gi 114303     577 ---lprdvaessLEFVSLVGIYDPPRtESKGAVELCHRAGIRVHMLTGDHpETAKAIAREVGIIppfisdrd-------- 645
gi 6688839    623 --etsrslieseLTFRGLIGLYDPPRpSSASAVHQCHEAGISVHMLTGDHpETAKAIAIEVGILpplssmsrv------- 693
gi 195540542  630 --eleredveanMTFLGLVGLYDPPRpETAGAVRKCKEAGITVRMLTGDHpGTAKAIAVDVGIVprnttrfs-------- 699
gi 114302     627 nitsnrataesdLVFLGLIGIYDPPRnETAGAVKKFHQAGINVHMLTGDFvGTAKAIAQEVGILptnlyhys-------- 698
gi 3121791    627 nitsnrataesdLVFLGLIGIYDPPRnETAGAVKKFHQAGINVHMLTGDFvGTAKAIAQEVGILptnlyhys-------- 698
gi 195540544  686 apglsraaaeqdFVFIGLLGIYDPPRaETRAAVEACKRAGIIVHMLTGDHpATAHAIAKEVAIVdgseg----------- 754
                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                                                                                         
gi 416667     699 ----qeivdsmvMTGSQFDGLSEEEVDDLPVLPLVIARCSPQTKVRMIEALHRRkKFCAMTGDGVNDSPSLKMANVGIAM 774
gi 6688837    729 -------ngtevMVASAFDSLSDAEIDALESLPLVLARCSPTTKVRMVEAMHRRkAFCVMTGDGVNDSPALKKSDVGIAM 801
gi 33352142   619 gdahvvpmsssvMTATEFDPLSEKEVDALDELPLVIARCTPSTKVRMIDALHRRkKYAAMTGDGVNDAPSLKKADVGIAM 698
gi 114303     646 -----pnmswmvMTGSQFDALSDEEVDSLKALCLVIARCAPQTKVKMIEALHRRkAFVAMTGDGVNDSPSLKQANVGIAM 720
gi 6688839    694 ---saavahamvMTASQFDALSDDEVDALPVLPLVIARCAPSTKVRMIEALHRRgRFCAMTGDGVNDSPSLRRADVGIAM 770
gi 195540542  700 ----kaeldsmvMTAAQFDKLSEDEIDALPQLPLVIARCAPQTKVRMIEALHRRgKFCAMTGDGVNDSPSLKMSDVGIAM 775
gi 114302     699 ----qeivdsmvMTGSQFDGLSEEEVDDLPVLPLVIARCSPQTKVRMIEALHRRkKFCTMTGDGVNDSPSLKMANVGIAM 774
gi 3121791    699 ----qeivdsmvMTGSQFDGLSEEEVDDLPVLPLVIARCSPQTKVRMIEALHRRkKFCAMTGDGVNDSPSLKMANVGIAM 774
gi 195540544  755 --------asavMTATQFDGLTDGEIDALEDLPLVVARCSPATKVRMIAAGKRRgRYLAMTGDGINDAPSLKQAPVGIGM 826
                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                                                                                         
gi 416667     775 GinGSDVSKEASDIVLSDDNFASILNAVEEGRRMTDNIQKFVLQLLAENVAQALYLIIGLVFRdengksVFPLSPVEVLW 854
gi 6688837    802 GlsGSDVAKEAADMVLTDDNFASIVTAIEEGRRLFDNIQKFLLHLLISNIAQVILLLIGLSFKdndgisVFPLSPLEILW 881
gi 33352142   699 Ga-GSDVAKTSSEIVLTDNNFATIVQAVAEGRRIFSNIKKFVVHLLSTNVGQVIVLLGGLAFKdgsgmsVFPLSPVQILF 777
gi 114303     721 GqnGSDVAKDASDIVLTDDNFSSIVNAIEEGRRMFDNIMRFVLHLLVSNVGEVILLVVGLAFRdevhlsVFPMSPVEILW 800
gi 6688839    771 GlsGSDVAKDASDIVLTDDNFASIVAAIEEGRRIFDNIQKFVLHVLAENIAQAGTLLIGLAFKdasglsVFPLAPVEIVW 850
gi 195540542  776 GmnGSDVAKDASDIVLVDDNFASIGNAIEEGRRMADNISKFVCHLLAQNVAQASVLLIGLAFKdetglsVFPLSPVEILY 855
gi 114302     775 GinGSDVSKEASDIVLSDDNFASILNAVEEGRRMTDNIQKFVLQLLAENVAQALYLIIGLVFRdengksVFPLSPVEVLW 854
gi 3121791    775 GinGSDVSKEASDIVLSDDNFASILNAVEEGRRMTDNIQKFVLQLLAENVAQALYLIIGLVFRdengksVFPLSPVEVLW 854
gi 195540544  827 Gt-GTDVAKDSSDLVLTDDRFDSIVKGIREGRAIFDNIQRFLIGLLVANVAEVLLLLCGLGVRdadeesVFPLAPVGILW 905
                         890       900       910       920       930       940       950       960
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                                                                                         
gi 416667     855 IIVVTSCFPAMGLGLEkaapDLMDRPPhdsevGIFtweVIIDTFAYGIIMTGSCMASFTGSLYGin-sGRLGHDCDgtyn 933
gi 6688837    882 ANLVTSSFLALGLGLEdaqpDVMQRPPhdlqvGIFtreLIVDKFVYGTAMGGLCLAAFTSVAYGmsgaDGLGEGCNedwt 961
gi 33352142   778 LNLITGTPPAMALGIErassTVMQVRPyl--kGLFtneLIADILVYGTFTGVLALLNWVLVIYAfg-nGDLGSQCNtssn 854
gi 114303     801 CNMITSSFPSMGLGMElaqpDVMERLPhdnkvGIFqksLIVDMMVYGFFLGVVSLMTWVVIMYGfg-tGNLSYDCNahyh 879
gi 6688839    851 IIMITSGLPDMGLGFEravpDIMARPPqslktGIFtleFIIDMIFYGLWITALCLASFVLRVYAwg-dGDLGSGCNehys 929
gi 195540542  856 IIMVTSGFPAMGLGMEkasmDVMKRKPrsnkwGIFspeMLIDLAVYGLWMAVLCLATFTLVEFGwg-nGELGINCNseys 934
gi 114302     855 IIVVTSCFPAMGLGLEkaapDLMDRPPhdsevGIFtweVIIDTFAYGIIMTGSCMASFTGSLYGin-sGRLGHDCDgtyn 933
gi 3121791    855 IIVVTSCFPAMGLGLEkaapDLMDRPPndsevGIFtweVIIDTFAYGIIMTGSCMASFTGSLYGin-sGRLGHDCDgtyn 933
gi 195540544  906 VNMVTASLPAIGLGLEpgesDIMERPPhdlraGVLsrsVIVDTLVYGSTMGITCLVAFLLMIYPig-gGQIAIDCNhssa 984
                         970       980       990      1000      1010      1020      1030      1040
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                                                                                         
gi 416667     934 s-scrdVYRSRSAAFATMTWCALILAWEVVdmrrsffrmhpdt--dspvkeffrsiwgNQFLFWSIIFGFVSAFPVVYIP 1010
gi 6688837    962 s-ecgvAFRARATTFATLTFLLLVTAWEAKhftrslfnmhpek--ysgplsvsktvwqNKFLFGAVSAGFVICFPVIYIP 1038
gi 33352142   855 lgacvtVFRARATVQMAFTWMILFHAYNCRhlraslftte---------gggrsrffaNKLMVASVFLGAVVPVLTLYIP 925
gi 114303     880 a-gcndVFKARSAVFAVVTFCILIMAVEVKnfdnslfnlhgipwgewnfryflhtlveNKFLAWAIALAAVSVFPTIYIP 958
gi 6688839    930 d-scetVFRARATTFACLTWFALFLAWELVdmrrsffrmqpgs--kkyftqwmvdvwrNKFLFWAIVGGFVTLFPTLYIP 1006
gi 195540542  935 p-pcdlVFRARASTFAVMTWFSLLLAWEVVdtrrsffnmrndg--qwynqwfkdtwgkNKFLFLCVVLGFFSVFPITYIP 1011
gi 114302     934 s-scrdVYRSRSAAFATMTWCALILAWEVVdmrrsffrmhpdt--dspvkeffrsiwgNQFLFWSIIFGFVSAFPVVYIP 1010
gi 3121791    934 s-scrdVYRSRSAAFATMTWCALILAWEVVdmrrsffrmhpdt--dspvkeffrsiwgNQFLFWSIIFGFVSAFPVVYIP 1010
gi 195540544  985 a-tcepIFQARSAVFTTLTLQLLLICWELIsmeksffsm-----------spakhlwkNPMLLWSVVFGIATIPIALYVP 1052
                        1050      1060      1070
                  ....*....|....*....|....*....|....*....
Feature 1                                                
gi 416667    1011 VINDKVFLhk-piGAEWGLAIAFTIAFWIGAELYKCGKR 1048
gi 6688837   1039 VINHVVFKhn-aiTWEWGVVMACVVVYVAIIEGWKAFKR 1076
gi 33352142   926 VLNTGIFKqe-glTWEWILVGITMVVFFLLSEFYKLLKR 963
gi 114303     959 VINRDVFKht-yiGWEWGVVAVAVMFYFFYVEIWKSIRR 996
gi 6688839   1007 VINHAVFKht-giSWEWGIVFVAAGLFFGGVEGWKWAKR 1044
gi 195540542 1012 GLNDIVFLht-giSWEWGIIFVCTGLFVGGIEAYKWGKR 1049
gi 114302    1011 VINDKVFLhk-piGAEWGLAIAFTIAFWIGAELYKCGKR 1048
gi 3121791   1011 VINDKVFLhk-piGAEWGLAIAFTIAFWIGAELYKCGKR 1048
gi 195540544 1053 KFNTDVFRhapmgGVGWGISIAMTVAFIAVVELWKALAR 1091

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